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5J2C	Ternary complex crystal structure of DNA polymerase Beta with C:A mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2J	Ternary complex crystal structure of DNA polymerase Beta with T:G mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2D	Ternary complex crystal structure of DNA polymerase Beta with C:C mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J29	Ternary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase beta, Downstream Primer Strand, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2G	Ternary complex crystal structure of DNA polymerase Beta with G:G mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2E	Ternary complex crystal structure of DNA polymerase Beta with C:T mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2I	Ternary complex crystal structure of DNA polymerase Beta with T:C mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase beta, Downstream Primer Strand, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2H	Ternary complex crystal structure of DNA polymerase Beta with G:T mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2B	Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
8IR3	human nuclear pre-60S ribosomal particle - State B' Descriptor: 28S rRNA, 5.8S rRNA, 5S RNA, ... Authors: Zhang, Y, Gao, N. Deposit date: 2023-03-17 Release date: 2023-08-09 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
5J2A	Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2F	Ternary complex crystal structure of DNA polymerase Beta with G:A mismatch at the primer terminus Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2016-03-29 Release date: 2016-10-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
6YBT	Structure of a human 48S translational initiation complex - eIF3bgi Descriptor: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit I Authors: Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. Deposit date: 2020-03-17 Release date: 2020-09-16 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (6 Å) Cite: Structure of a human 48Stranslational initiation complex. Science, 369, 2020
8BI7	Binary structure of 14-3-3s and PKR phosphopeptide Descriptor: 14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide Authors: Somsen, B.A, Ottmann, C. Deposit date: 2022-11-01 Release date: 2023-03-29 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach. J.Am.Chem.Soc., 145, 2023
4MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY Descriptor: DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... Authors: Cheng, X. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
4M8O	TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Sauer-Eriksson, A.E, Hogg, M, Osterman, P, Johansson, E. Deposit date: 2013-08-13 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for processive DNA synthesis by yeast DNA polymerase epsilon. Nat.Struct.Mol.Biol., 21, 2014
6NKX	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with "hot-spot sequence" with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKR	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKU	Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NL0	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with "hot-spot sequence" with beta-gamma CF2 analogue of dGTP Descriptor: 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKS	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with beta-gamma CHF analog of dGTP Descriptor: 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.349 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKW	Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with beta-gamma-methylene dGTP Descriptor: 2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2019-01-07 Release date: 2020-01-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6CR6	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH-CH3, beta, gamma dATP analogue Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy({(R)-hydroxy[(1S)-1-phosphonoethyl]phosphoryl}oxy)phosphoryl]adenosine, DNA polymerase beta, Downstream Primer Strand, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-08-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.097 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CTN	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CFCL,beta-gamma dTTP analogue Descriptor: 5'-O-[(R)-{[(R)-[(S)-chloro(fluoro)phosphonomethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-23 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CR9	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CFCL, beta, gamma dATP analogue Descriptor: 9-{5-O-[(R)-{[(R)-[(S)-chloro(fluoro)phosphonomethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2-deoxy-alpha-D-threo-pentofuranosyl}-9H-purin-6-amine, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-07-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018

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