PDB: 672 resultsInfo pagesStatus searchChemie searchBIRD

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3U92	Crystal structure of the GluK3 ligand binding domain complex with kainate and zinc: P2221 form Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, Glutamate receptor, ... Authors: Kumar, J, Mayer, M.L. Deposit date: 2011-10-17 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface. Neuron, 76, 2012
3TZA	Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution Descriptor: (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid, Glutamate receptor 2,Glutamate receptor 2, SULFATE ION Authors: Frydenvang, K, Kastrup, J.S. Deposit date: 2011-09-27 Release date: 2011-10-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure J.Med.Chem., 54, 2011
3U94	Crystal structure of the GluK3 ligand binding domain complex with glutamate and zinc: P21212 form Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Kumar, J, Mayer, M.L. Deposit date: 2011-10-17 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.962 Å) Cite: Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface. Neuron, 76, 2012
3U93	Crystal structure of the GluK3 ligand binding domain complex with glutamate and zinc: P2221 form Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... Authors: Kumar, J, Mayer, M.L. Deposit date: 2011-10-17 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.881 Å) Cite: Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface. Neuron, 76, 2012
7RZ8	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2 Authors: Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ6	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZA	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 Authors: Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.26 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RYZ	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 Authors: Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-26 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RYY	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-26 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ5	Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775 Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid Authors: Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ9	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L in the apo state Descriptor: Glutamate receptor 2 Authors: Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ4	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775 Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ... Authors: Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7RZ7	Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 Authors: Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2021-08-27 Release date: 2021-10-27 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
7SAB	Phencyclidine-bound GluN1a-GluN2B NMDA receptors Descriptor: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2021-09-22 Release date: 2022-07-20 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAD	Memantine-bound GluN1a-GluN2B NMDA receptors Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2021-09-22 Release date: 2022-07-20 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAA	Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2021-09-22 Release date: 2022-07-20 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAC	S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution Descriptor: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Chou, T.-H, Furukawa, H. Deposit date: 2021-09-22 Release date: 2022-07-20 Last modified: 2022-10-26 Method: ELECTRON MICROSCOPY (3.69 Å) Cite: Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7TEB	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-04 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (4.23 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TER	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-05 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (5.23 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEE	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-04 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (6.59 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TET	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-05 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (4.45 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEQ	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-05 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (7.51 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TE9	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1 Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-04 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (3.92 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TES	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation Descriptor: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... Authors: Tajima, N, Furukawa, H. Deposit date: 2022-01-05 Release date: 2022-03-02 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TNK	Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera Authors: Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2022-01-21 Release date: 2022-04-20 Last modified: 2022-05-18 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Opening of glutamate receptor channel to subconductance levels. Nature, 605, 2022

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