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9FMD
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BU of 9fmd by Molmil
Integrative model of the human post-catalytic spliceosome (P-complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Rothe, P, Plaschka, C, Vorlaender, M.K.
Deposit date:2024-06-05
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 2024
1TWF
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BU of 1twf by Molmil
RNA polymerase II complexed with UTP at 2.3 A resolution
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2004-06-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1TWC
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BU of 1twc by Molmil
RNA polymerase II complexed with GTP
Descriptor: DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2004-06-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1TWA
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BU of 1twa by Molmil
RNA polymerase II complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2004-06-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
2LKZ
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BU of 2lkz by Molmil
Solution structure of the second RRM domain of RBM5
Descriptor: RNA-binding protein 5
Authors:Song, Z, Wu, P, Zhang, J, Wu, J, Shi, Y.
Deposit date:2011-10-23
Release date:2012-08-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second RRM domain of RBM5 and its unusual binding characters for different RNA targets
Biochemistry, 2012
5ZEG
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BU of 5zeg by Molmil
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site
Descriptor: RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*(1MA)P*CP*GP*UP*CP*GP*AP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3')
Authors:Kanazawa, H, Baba, F, Koganei, M, Kondo, J.
Deposit date:2018-02-27
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.
Nucleic Acids Res., 45, 2017
5ZEM
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BU of 5zem by Molmil
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in the presence of gentamicin
Descriptor: RNA (5'-R(P*UP*GP*CP*GP*UP*CP*(1MA)P*CP*GP*UP*CP*GP*AP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3')
Authors:Kanazawa, H, Baba, F, Koganei, M, Kondo, J.
Deposit date:2018-02-27
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.
Nucleic Acids Res., 45, 2017
6EDE
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BU of 6ede by Molmil
tRNA 2'-phosphotransferase
Descriptor: Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate
Authors:Shuman, S, Goldgur, Y, Banerjee, A.
Deposit date:2018-08-09
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
Nat Commun, 10, 2019
6E3A
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BU of 6e3a by Molmil
tRNA 2'-phosphotransferase
Descriptor: COENZYME A, Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate
Authors:Shuman, S, Goldgur, Y, Banerjee, A.
Deposit date:2018-07-13
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation.
Nat Commun, 10, 2019
7UVT
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BU of 7uvt by Molmil
Kinetically trapped misfolded state of the Tetrahymena ribozyme
Descriptor: RNA (386-MER)
Authors:Bonilla, S.L, Vicens, Q, Kieft, J.S.
Deposit date:2022-05-02
Release date:2022-08-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA.
Sci Adv, 8, 2022
3JSB
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BU of 3jsb by Molmil
Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein
Descriptor: RNA-directed RNA polymerase
Authors:Morin, B, Jamal, S, Ferron, F.P, Coutard, B, Bricogne, G, Canard, B, Vonrhein, C, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog., 6, 2010
7F1E
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BU of 7f1e by Molmil
Structure of METTL6 bound with SAM
Descriptor: S-ADENOSYLMETHIONINE, tRNA N(3)-methylcytidine methyltransferase METTL6
Authors:Li, S, Liao, S, Xu, C.
Deposit date:2021-06-09
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural basis for METTL6-mediated m3C RNA methylation.
Biochem.Biophys.Res.Commun., 589, 2021
3ENB
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BU of 3enb by Molmil
Crystal Structure of PRP8 core domain IV
Descriptor: Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M.
Deposit date:2008-09-25
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Nat.Struct.Mol.Biol., 15, 2008
5IWW
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BU of 5iww by Molmil
Crystal structure of RNA editing factor of designer PLS-type PPR/9R protein in complex with MORF9/RIP9
Descriptor: Multiple organellar RNA editing factor 9, chloroplastic, PLS9-PPR
Authors:Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P.
Deposit date:2016-03-23
Release date:2017-03-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing
Nat Plants, 3, 2017
8JED
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BU of 8jed by Molmil
Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Descriptor: mRNA-capping enzyme regulatory subunit OPG124
Authors:Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X.
Deposit date:2023-05-15
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors.
Int.J.Biol.Macromol., 253, 2023
2CD6
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BU of 2cd6 by Molmil
Refinement of RNase P P4 stemloop structure using residual dipolar coupling data, C70U mutant cobalt(III) hexammine complex
Descriptor: 5'-R(*GP*GP*AP*AP*GP*UP*UP*CP*CP*GP *UP*CP*UP*UP*CP*GP*GP*AP*CP*CP*GP*GP*CP*UP*UP*CP*C)-3', COBALT HEXAMMINE(III)
Authors:Schmitz, M.
Deposit date:2006-01-19
Release date:2007-05-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:

2CD5
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BU of 2cd5 by Molmil
Refinement of RNase P P4 stemloop structure using residual dipolar couplings - cobalt(III) hexammine complex structure
Descriptor: 5'-R(*GP*GP*AP*AP*GP*UP*CP*CP*GP*GP*UP*CP*UP *UP*CP*GP*GP*AP*CP*CP*GP*GP*CP*UP*UP*CP*C)-3', COBALT HEXAMMINE(III)
Authors:Schmitz, M.
Deposit date:2006-01-19
Release date:2007-05-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:

2CD3
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BU of 2cd3 by Molmil
Refinement of RNase P P4 stemloop structure using residual dipolar coupling data - C70U mutant
Descriptor: 5'-R(*GP*GP*AP*AP*GP*UP*UP*CP*GP*GP *UP*CP*UP*UP*CP*GP*GP*AP*CP*CP*GP*GP*CP*UP*UP*CP*C)-3'
Authors:Schmitz, M.
Deposit date:2006-01-19
Release date:2007-05-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:

5XJ0
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BU of 5xj0 by Molmil
T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ooi, W.Y, Murayama, Y, Mekler, V, Minakhin, L, Severinov, K, Yokoyama, S, Sekine, S.
Deposit date:2017-04-28
Release date:2017-12-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.004 Å)
Cite:A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation
Nucleic Acids Res., 46, 2018
6E4N
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BU of 6e4n by Molmil
Structure of the T. brucei TbRGG2 RRM domain: apo R3 crystal form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4O
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BU of 6e4o by Molmil
Structure of apo T. brucei RRM: P4(1)2(1)2 form
Descriptor: RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
1R5U
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BU of 1r5u by Molmil
RNA POLYMERASE II TFIIB COMPLEX
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D.
Deposit date:2003-10-13
Release date:2004-02-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.
Science, 303, 2004
8FMA
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BU of 8fma by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FM9
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BU of 8fm9 by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB
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BU of 8fmb by Molmil
Nodavirus RNA replication protein A polymerase domain, local refinement
Descriptor: RNA-directed RNA polymerase
Authors:Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
Deposit date:2022-12-22
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023

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