3ENB

Crystal Structure of PRP8 core domain IV

Summary for 3ENB

Entry DOI	10.2210/pdb3enb/pdb
Descriptor	Pre-mRNA-processing-splicing factor 8 (2 entities in total)
Functional Keywords	prp8 domain iv, beta finger, rnase h, spliceosome, u5-220k, disease mutation, mrna processing, mrna splicing, nucleus, phosphoprotein, retinitis pigmentosa, rna-binding, sensory transduction, vision, rna binding protein
Biological source	Homo sapiens
Cellular location	Nucleus speckle : Q6P2Q9
Total number of polymer chains	2
Total formula weight	51077.57
Authors	Schellenberg, M.J.,Ritchie, D.B.,MacMillan, A.M. (deposition date: 2008-09-25, release date: 2008-10-07, Last modification date: 2024-02-21)
Primary citation	Ritchie, D.B.,Schellenberg, M.J.,Gesner, E.M.,Raithatha, S.A.,Stuart, D.T.,Macmillan, A.M. Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat.Struct.Mol.Biol., 15:1199-1205, 2008 Cited by PubMed: 18836455 DOI: 10.1038/nsmb.1505 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation