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4N0B
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BU of 4n0b by Molmil
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of GabT
Descriptor: ACETYL GROUP, CALCIUM ION, HTH-type transcriptional regulatory protein GabR, ...
Authors:Edayathumangalam, R, Wu, R, Garcia, R, Wang, Y, Wang, W, Kreinbring, C.A, Bach, A, Liao, J, Stone, T, Terwilliger, T, Hoang, Q.Q, Belitsky, B.R, Petsko, G.A, Ringe, D, Liu, D.
Deposit date:2013-10-01
Release date:2013-10-30
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
Proc.Natl.Acad.Sci.USA, 110, 2013
4TV7
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BU of 4tv7 by Molmil
Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution
Descriptor: HTH-type transcriptional regulatory protein GabR
Authors:Goto, M, Okuda, K, Yoshimura, T.
Deposit date:2014-06-26
Release date:2014-12-24
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Mol. Microbiol., 95, 2015
6M4O
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BU of 6m4o by Molmil
Cryo-EM structure of the monomeric SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-03-08
Release date:2021-02-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
6M4N
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BU of 6m4n by Molmil
Cryo-EM structure of the dimeric SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-03-07
Release date:2021-02-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
4MGR
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BU of 4mgr by Molmil
The crystal structure of Bacillus subtilis GabR, an autorepressor and PLP- and GABA-dependent transcriptional activator of gabT
Descriptor: ACETATE ION, HTH-type transcriptional regulatory protein GabR, IMIDAZOLE, ...
Authors:Wu, R, Edayathumangalam, R, Garcia, R, Wang, Y, Wang, W, Kreinbring, C.A, Bach, A, Liao, J, Stone, T, Terwilliger, T, Hoang, Q.Q, Belitsky, B.R, Petsko, G.A, Ringe, D, Liu, D.
Deposit date:2013-08-28
Release date:2013-10-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
Proc.Natl.Acad.Sci.USA, 110, 2013
8C80
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BU of 8c80 by Molmil
Cryo-EM structure of the yeast SPT-Orm1-Monomer complex
Descriptor: 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ERGOSTEROL, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, ...
Authors:Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F.
Deposit date:2023-01-18
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the ceramide-bound SPOTS complex.
Nat Commun, 14, 2023
8C81
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BU of 8c81 by Molmil
Cryo-EM structure of the yeast SPT-Orm1-Sac1 complex
Descriptor: 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ERGOSTEROL, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, ...
Authors:Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F.
Deposit date:2023-01-18
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the ceramide-bound SPOTS complex.
Nat Commun, 14, 2023
8C82
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BU of 8c82 by Molmil
Cryo-EM structure of the yeast SPT-Orm1-Dimer complex
Descriptor: 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]hexacosanamide, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Schaefer, J, Koerner, C, Parey, K, Januliene, D, Moeller, A, Froehlich, F.
Deposit date:2023-01-18
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the ceramide-bound SPOTS complex.
Nat Commun, 14, 2023
7CQI
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BU of 7cqi by Molmil
Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-08-11
Release date:2021-02-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
7CQK
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BU of 7cqk by Molmil
Cryo-EM structure of the substrate-bound SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-08-11
Release date:2021-02-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
7K0I
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BU of 7k0i by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0K
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BU of 7k0k by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound
Descriptor: 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0N
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BU of 7k0n by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0O
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BU of 7k0o by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0J
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BU of 7k0j by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0Q
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BU of 7k0q by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound
Descriptor: Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0L
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BU of 7k0l by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound
Descriptor: Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0P
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BU of 7k0p by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0M
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BU of 7k0m by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
Deposit date:2020-09-04
Release date:2021-02-24
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
8IAK
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BU of 8iak by Molmil
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A-N71A) complex
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Protein ORM2, Serine palmitoyltransferase 2, ...
Authors:Xie, T, Gong, X.
Deposit date:2023-02-08
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
Cell Rep, 43, 2024
8IAJ
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BU of 8iaj by Molmil
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex
Descriptor: N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, Protein ORM2, ...
Authors:Xie, T, Gong, X.
Deposit date:2023-02-08
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
Cell Rep, 43, 2024
8IAM
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BU of 8iam by Molmil
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex
Descriptor: Chimera of Long chain base biosynthesis protein 1 and Serine palmitoyltransferase 1, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Xie, T, Gong, X.
Deposit date:2023-02-08
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
Cell Rep, 43, 2024
7YJ1
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BU of 7yj1 by Molmil
Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Xie, T, Liu, P, Gong, X.
Deposit date:2022-07-19
Release date:2023-07-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
7YIU
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BU of 7yiu by Molmil
Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex
Descriptor: HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)HEXANAMIDE, ORM1-like protein 3, ...
Authors:Xie, T, Liu, P, Gong, X.
Deposit date:2022-07-18
Release date:2023-07-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
7YJ2
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BU of 7yj2 by Molmil
Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Xie, T, Liu, P, Gong, X.
Deposit date:2022-07-19
Release date:2023-07-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023

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