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1W4P
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BU of 1w4p by Molmil
Binding of Nonnatural 3'-Nucleotides to Ribonuclease A
Descriptor: 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, PANCREATIC RIBONUCLEASE A
Authors:Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T.
Deposit date:2004-07-27
Release date:2005-02-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
6XHC
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BU of 6xhc by Molmil
Structure of glycinyl 5'-O-adenosine phosphoramidate
Descriptor: 2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]ethanoic acid, Ribonuclease pancreatic
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2020-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
2RLN
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BU of 2rln by Molmil
THERMODYNAMIC AND STRUCTURAL CONSEQUENCES OF CHANGING A SULPHUR ATOM TO A METHYLENE GROUP IN THE M13NLE MUTATION IN RIBONUCLEASE S
Descriptor: RIBONUCLEASE, RIBONUCLEASE S (S-PROTEIN), SULFATE ION
Authors:Ratnaparkhi, G, Varadarajan, R.
Deposit date:1994-07-11
Release date:1994-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S.
Biochemistry, 33, 1994
3DJO
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BU of 3djo by Molmil
Bovine Seminal Ribonuclease uridine 2' phosphate complex
Descriptor: ACETATE ION, PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Seminal ribonuclease
Authors:Dossi, K, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G.
Deposit date:2008-06-24
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors
Eur.J.Med.Chem., 44, 2009
2RNS
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BU of 2rns by Molmil
REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES
Descriptor: RIBONUCLEASE S, SULFATE ION
Authors:Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M.
Deposit date:1992-02-19
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures.
Biochemistry, 31, 1992
3DH6
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BU of 3dh6 by Molmil
Crystal structure of bovine pancreatic ribonuclease A variant (V47A)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K.
Deposit date:2008-06-17
Release date:2008-07-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability
Proteins, 77, 2009
2RNF
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BU of 2rnf by Molmil
X-RAY CRYSTAL STRUCTURE OF HUMAN RIBONUCLEASE 4 IN COMPLEX WITH D(UP)
Descriptor: 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, RIBONUCLEASE 4
Authors:Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Ruth, F.X, Coll, M.
Deposit date:1998-11-03
Release date:1999-11-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity.
J.Mol.Biol., 285, 1999
5JML
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BU of 5jml by Molmil
X-ray structure of the complex between bovine pancreatic ribonuclease and penthachlorocarbonyliridate(III) (2 months of soaking)
Descriptor: CARBON MONOXIDE, CHLORIDE ION, IRIDIUM ION, ...
Authors:Caterino, M, Petruk, A.A, Vergara, A, Ferraro, G, Merlino, A.
Deposit date:2016-04-29
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Mapping the protein-binding sites for iridium(iii)-based CO-releasing molecules.
Dalton Trans, 45, 2016
5JLG
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BU of 5jlg by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand
Descriptor: DIMETHYL SULFOXIDE, RUTHENIUM ION, Ribonuclease pancreatic, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-04-27
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand.
Dalton Trans, 45, 2016
5JMG
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BU of 5jmg by Molmil
X-ray structure of the complex between bovine pancreatic ribonuclease and pentachlorocarbonyliridate(III) (4 days of soaking)
Descriptor: CARBON MONOXIDE, CHLORIDE ION, IRIDIUM ION, ...
Authors:Caterino, M, Petruk, A.A, Vergara, A, Ferraro, G, Merlino, A.
Deposit date:2016-04-29
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mapping the protein-binding sites for iridium(iii)-based CO-releasing molecules.
Dalton Trans, 45, 2016
8FHM
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BU of 8fhm by Molmil
RNase A-Uridine 5'-Hexaphosphate (RNaseA.p6U)
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic
Authors:Park, G, Cummins, C.
Deposit date:2022-12-14
Release date:2023-12-20
Method:SOLUTION SCATTERING (1.79 Å), X-RAY DIFFRACTION
Cite:Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A inhibitors.
To Be Published
8GGG
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BU of 8ggg by Molmil
RNase A-Adenosine 5'-Hexaphosphate (RNaseA.p6A)
Descriptor: GLYCEROL, Ribonuclease pancreatic, adenosine 5'-hexaphosphate
Authors:Park, G, Cummins, C.
Deposit date:2023-03-08
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A Inhibitiors.
To Be Published
8GC9
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BU of 8gc9 by Molmil
RNase A-Uridine 5'-Heptaphosphate (RNase A.p7U)
Descriptor: Ribonuclease pancreatic, uridine 5'-heptaphosphate
Authors:Park, G, Cummins, C.
Deposit date:2023-03-01
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A Inhibitors.
To Be Published
9RAT
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BU of 9rat by Molmil
EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
Descriptor: RIBONUCLEASE A
Authors:Tilton Jr, R.F, Dewan, J.C, Petsko, G.A, Gilbert, W.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
1EIE
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BU of 1eie by Molmil
CRYSTAL STRUCTURE OF F120W MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A
Authors:Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
Deposit date:2000-02-25
Release date:2002-02-13
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
2G4W
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BU of 2g4w by Molmil
anomalous substructure of ribonuclease A (C2)
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION
Authors:Mueller-Dieckmann, C, Weiss, M.S.
Deposit date:2006-02-22
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
9EO8
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BU of 9eo8 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure D)
Descriptor: AMMONIA, CHLORIDE ION, PLATINUM (II) ION, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
9RSA
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BU of 9rsa by Molmil
CRYSTAL STRUCTURE OF TWO COVALENT NUCLEOSIDE DERIVATIVES OF RIBONUCLEASE A
Descriptor: 3'-DEOXY-3'-ACETAMIDO-URIDINE, RIBONUCLEASE A
Authors:Nachman, J, Wlodawer, A.
Deposit date:1989-08-28
Release date:1991-04-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of two covalent nucleoside derivatives of ribonuclease A.
Biochemistry, 29, 1990
6XHE
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BU of 6xhe by Molmil
Structure of beta-prolinyl 5'-O-adenosine phosphoramidate
Descriptor: 5'-O-[(S)-[(3S)-3-carboxypyrrolidin-1-yl](hydroxy)phosphoryl]adenosine, ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
6XHF
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BU of 6xhf by Molmil
Structure of Phenylalanyl-5'-O-adenosine phosphoramidate
Descriptor: (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, Ribonuclease pancreatic
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
9EO5
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BU of 9eo5 by Molmil
X-ray structure of the adduct formed upon reaction of picoplatin with bovine pancreatic ribonuclease (structure C)
Descriptor: AMMONIA, PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Ferraro, G, Merlino, A.
Deposit date:2024-03-14
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A.
Dalton Trans, 53, 2024
6XHD
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BU of 6xhd by Molmil
Structure of Prolinyl-5'-O-adenosine phosphoramidate
Descriptor: (2~{S})-1-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]pyrrolidine-2-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, ...
Authors:Pallan, P.S, Egli, M.
Deposit date:2020-06-18
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
1EID
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BU of 1eid by Molmil
CRYSTAL STRUCTURE OF F120G MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A
Authors:Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
Deposit date:2000-02-25
Release date:2002-02-13
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
2G4X
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BU of 2g4x by Molmil
Anomalous substructure od ribonuclease A (P3221)
Descriptor: CHLORIDE ION, SULFATE ION, ribonuclease pancreatic
Authors:Mueller-Dieckmann, C, Weiss, M.S.
Deposit date:2006-02-22
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
1EOW
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BU of 1eow by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A COMPLEXED WITH URIDYLYL(2',5')GUANOSINE (NON-PRODUCTIVE BINDING)
Descriptor: RIBONUCLEASE PANCREATIC, SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
Authors:Vitagliano, L, Merlino, A, Zagari, A, Mazzarella, L.
Deposit date:2000-03-24
Release date:2000-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine.
Protein Sci., 9, 2000

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