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7JP3
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BU of 7jp3 by Molmil
Des-B29,B30-insulin
Descriptor: CHLORIDE ION, Insulin B chain,Insulin A chain, PHENOL, ...
Authors:Yoder, J, Weiss, M.A, DiMarchi, R, Zaykov, A.
Deposit date:2020-08-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Des-B29,B30-insulin
To Be Published
7NHU
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BU of 7nhu by Molmil
Crystal structure of desB30 insulin produced by cell free protein synthesis
Descriptor: Insulin
Authors:Johansson, E.
Deposit date:2021-02-11
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein.
Protein Expr.Purif., 186, 2021
7INS
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BU of 7ins by Molmil
STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z
Descriptor: GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ...
Authors:Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F.
Deposit date:1991-09-03
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of porcine insulin cocrystallized with clupeine Z.
Acta Crystallogr.,Sect.B, 47, 1991
7Z5L
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BU of 7z5l by Molmil
Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO)
Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ...
Authors:van den Elsen, J.M.H, Wahid, A.A, Crennell, C.
Deposit date:2022-03-09
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
7Z5Q
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BU of 7z5q by Molmil
Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP)
Descriptor: Insulin, Insulin A chain, SULFATE ION
Authors:van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J.
Deposit date:2022-03-09
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
8Z4B
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BU of 8z4b by Molmil
Crystal structure of LysB22-AspB28 insulin analog at ambient structure
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Ayan, E, Demirci, H.
Deposit date:2024-04-17
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of LysB22-AspB28 insulin analog at ambient structure
To Be Published
4XC4
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BU of 4xc4 by Molmil
Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide
Descriptor: CHLORIDE ION, Insulin, SODIUM ION, ...
Authors:Bracey, A.W, Magis, A.T, Buschard, K, Osterbye, T, Bailey, K.M, Ostrov, D.A.
Deposit date:2014-12-17
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide
To Be Published
5AIY
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BU of 5aiy by Molmil
R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE
Descriptor: PHENOL, PROTEIN (INSULIN)
Authors:O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J.
Deposit date:1998-12-29
Release date:2000-02-28
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
4M4F
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BU of 4m4f by Molmil
Radiation damage study of Cu T6-insulin - 0.01 MGy
Descriptor: COPPER (II) ION, Insulin
Authors:Frankaer, C.G, Harris, P, Stahl, K.
Deposit date:2013-08-07
Release date:2014-01-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives.
Acta Crystallogr.,Sect.D, 70, 2014
4M4M
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BU of 4m4m by Molmil
The structure of Ni T6 bovine insulin
Descriptor: Insulin, NICKEL (II) ION
Authors:Frankaer, C.G, Harris, P, Stahl, K.
Deposit date:2013-08-07
Release date:2014-01-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives.
Acta Crystallogr.,Sect.D, 70, 2014
4M4I
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BU of 4m4i by Molmil
Radiation damage study of Cu T6-insulin - 0.12 MGy
Descriptor: COPPER (II) ION, Insulin
Authors:Frankaer, C.G, Harris, P, Stahl, K.
Deposit date:2013-08-07
Release date:2014-01-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives.
Acta Crystallogr.,Sect.D, 70, 2014
4M4L
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BU of 4m4l by Molmil
The structure of Cu T6 bovine insulin
Descriptor: COPPER (II) ION, Insulin
Authors:Frankaer, C.G, Harris, P, Stahl, K.
Deposit date:2013-08-07
Release date:2014-01-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives.
Acta Crystallogr.,Sect.D, 70, 2014
7AC4
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BU of 7ac4 by Molmil
Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source
Descriptor: Insulin, R-1,2-PROPANEDIOL, SODIUM ION
Authors:Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M.
Deposit date:2020-09-09
Release date:2021-09-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
8SBD
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BU of 8sbd by Molmil
Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments
Descriptor: Insulin A chain, Insulin B chain
Authors:Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C.
Deposit date:2023-04-03
Release date:2023-08-30
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of insulin fibrillation.
Sci Adv, 9, 2023
2ZP6
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BU of 2zp6 by Molmil
Crystal structure of Bovine Insulin (Hexameric form)
Descriptor: Insulin A chain, Insulin B chain, ZINC ION
Authors:Jaimohan, S.M, Naresh, M.D, Mandal, A.B.
Deposit date:2008-06-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of Bovine Insulin (Hexameric form)
To be Published
8RRP
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BU of 8rrp by Molmil
Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
Descriptor: ACETATE ION, Insulin, Insulin B chain
Authors:Schluckebier, G, Johansson, E.
Deposit date:2024-01-23
Release date:2024-07-10
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Nat Commun, 15, 2024
4NIB
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BU of 4nib by Molmil
Crystal structure of human insulin mutant B20 D-ala, B23 D-ala
Descriptor: Insulin A chain, Insulin B chain
Authors:Menting, J.G, Lawrence, M.C.
Deposit date:2013-11-05
Release date:2014-08-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protective hinge in insulin opens to enable its receptor engagement.
Proc.Natl.Acad.Sci.USA, 111, 2014
8HGZ
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BU of 8hgz by Molmil
Crystal structure of insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:DeMirci, H, Ayan, E.
Deposit date:2022-11-16
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions
Crystals, 13, 2023
4RXW
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BU of 4rxw by Molmil
Crystal Structure of the cobalt human insulin derivative
Descriptor: COBALT (II) ION, Insulin A chain, Insulin B chain
Authors:Prugovecki, B, Ivetic, N, Matkovic-Calogovic, D.
Deposit date:2014-12-12
Release date:2015-01-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal Structure of the cobalt human insulin derivative
TO BE PUBLISHED
8GSG
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BU of 8gsg by Molmil
T3R3 form of Human insulin with single Zn
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Zhu, Z.L.
Deposit date:2022-09-06
Release date:2023-03-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:T3R3 insulin with single Zn
To Be Published
2ZPP
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BU of 2zpp by Molmil
Neutron crystal structure of cubic insulin at pD9
Descriptor: Insulin A chain, Insulin B chain
Authors:Ishikawa, T, Tanaka, I, Niimura, N.
Deposit date:2008-07-26
Release date:2008-10-28
Last modified:2023-11-01
Method:NEUTRON DIFFRACTION (2.5 Å)
Cite:An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis
Biochem.Biophys.Res.Commun., 376, 2008
8HSF
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BU of 8hsf by Molmil
Insulin triple mutant INS-RQD
Descriptor: Insulin A chain, Insulin B chain
Authors:Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A.
Deposit date:2022-12-19
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insulin triple mutant INS-RQD
To Be Published
8HSK
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BU of 8hsk by Molmil
Insulin single mutant INS-Q
Descriptor: Insulin A chain, Insulin B chain, SULFATE ION
Authors:Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A.
Deposit date:2022-12-19
Release date:2023-12-20
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Insulin single mutant INS-Q
To Be Published
4P65
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BU of 4p65 by Molmil
Crystal structure of an cyclohexylalanine substituted insulin analog.
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Pandyarajan, V, Wan, Z, Weiss, M.A.
Deposit date:2014-03-21
Release date:2014-10-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Aromatic Anchor at an Invariant Hormone-Receptor Interface: FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN.
J.Biol.Chem., 289, 2014
8RVT
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BU of 8rvt by Molmil
Structure of full-length human insulin fibrils
Descriptor: Insulin A chain, Insulin B chain
Authors:Bardiaux, B, Suladze, S, Reif, B.
Deposit date:2024-02-02
Release date:2024-05-29
Last modified:2024-06-12
Method:SOLID-STATE NMR
Cite:Atomic resolution structure of full-length human insulin fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024

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