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7NER	Crystal structure of the v-Src SH3 domain Q128R mutant Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NET	Crystal structure of the v-Src SH3 domain W95R-I96T mutant Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NES	Crystal structure of the v-Src SH3 domain N117D-V124L mutant Descriptor: GLYCINE, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.35 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
4ZNX	Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12 Descriptor: APP12, Tyrosine-protein kinase Fyn Authors: Camara-Artigas, A. Deposit date: 2015-05-05 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase. Acta Crystallogr.,Sect.F, 72, 2016
7YXW	Structure of the p22phox A200G mutant in complex with p47phox peptide Descriptor: Cytochrome b-245 light chain, Neutrophil cytosol factor 1 Authors: Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z. Deposit date: 2022-02-16 Release date: 2022-03-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics Acs Med.Chem.Lett., 13, 2022
8KDX	Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current Descriptor: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn Authors: Padavattan, S, Jos, S. Deposit date: 2023-08-10 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (1.01 Å) Cite: Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current. J.Mol.Biol., 436, 2024
8CHH	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction method for spin-diffusion with PDB 2NUZ as reference Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-08 Release date: 2023-03-08 Last modified: 2024-06-19 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
8CF4	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-02 Release date: 2023-03-08 Last modified: 2024-06-19 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
8CHG	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction for dipolar truncation with PDB 2NUZ Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-08 Release date: 2023-03-08 Last modified: 2024-06-19 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
1K76	Solution Structure of the C-terminal Sem-5 SH3 Domain (Minimized Average Structure) Descriptor: SEX MUSCLE ABNORMAL PROTEIN 5 Authors: Ferreon, J, Volk, D, Luxon, B, Gorenstein, D, Hilser, V. Deposit date: 2001-10-18 Release date: 2003-05-20 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
5NP3	Abl2 SH3 Descriptor: Abelson tyrosine-protein kinase 2 Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5NP5	Abl2 SH3 pTyr116/161 Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5NP2	Abl1 SH3 pTyr89/134 Descriptor: Tyrosine-protein kinase ABL1 Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5OAZ	Crystal structure of the Abl-SH3 domain at pH 7.5 Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.03 Å) Cite: Crystal structure of the Abl-SH3 domain at pH 7.5 to be published
8WFF	The Crystal Structure of LYN from Biortus. Descriptor: CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn Authors: Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. Deposit date: 2023-09-19 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The Crystal Structure of LYN from Biortus. To Be Published
7CFZ	SH3 domain of NADPH oxidase activator 1 Descriptor: NADPH oxidase activator 1 Authors: Kim, M, Park, J.H, Attri, P, Lee, W. Deposit date: 2020-06-29 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. Int.J.Biol.Macromol., 163, 2020
7TZK	EPS8 SH3 Domain with NleH1 PxxDY Motif Descriptor: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog Authors: Grishin, A.M, Cygler, M. Deposit date: 2022-02-15 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli Proc.Natl.Acad.Sci.USA, 119, 2022
5IHN	Crystal Structure of the alpha spectrin SH3 domain mutant N47G Descriptor: FORMIC ACID, SODIUM ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain mutant N47G to be published
5IH2	Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Adapter molecule crk, DI(HYDROXYETHYL)ETHER, ... Authors: Bhatt, V.S, Zeng, D, Krieger, I, Sacchettini, J.C, Cho, J.-H. Deposit date: 2016-02-28 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl. Biophys.J., 110, 2016
5IHI	Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G to be published
5L23	Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand Descriptor: Adapter molecule crk, C3G derived peptide, DI(HYDROXYETHYL)ETHER Authors: Bhatt, V.S, Krieger, I, Sacchettini, J, Cho, J.-H. Deposit date: 2016-07-30 Release date: 2016-09-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand To Be Published
3FJ5	Crystal structure of the c-src-SH3 domain Descriptor: ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A. Deposit date: 2008-12-14 Release date: 2009-03-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding Febs Lett., 583, 2009
5ZAU	Complex of the human FYN SH3 and monobody binder Descriptor: Monobody Binder, Tyrosine-protein kinase Fyn Authors: Reddy, P.P, Gulyani, A, Das, R. Deposit date: 2018-02-09 Release date: 2019-09-11 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells. Elife, 9, 2020
6A9C	Crystal Structure c-terminal SH3 domain of Myosin IB from Entamoeba histolytica bound to EhFP10(GEF) peptide. Descriptor: Peptide from Rho guanine nucleotide exchange factor, SULFATE ION, Unconventional myosin IB Authors: Gautam, G, Gourinath, S. Deposit date: 2018-07-13 Release date: 2019-06-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.98 Å) Cite: EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica. Plos Pathog., 15, 2019
6XVN	Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1 Descriptor: Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Plaza-Garrido, M. Deposit date: 2020-01-22 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020

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