5IH2
Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl
Summary for 5IH2
Entry DOI | 10.2210/pdb5ih2/pdb |
Descriptor | Adapter molecule crk, Proline rich Peptide, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | sh3 domain polyproline ii motif, signaling protein |
Biological source | Mus musculus (Mouse) More |
Cellular location | Cytoplasm : Q64010 |
Total number of polymer chains | 4 |
Total formula weight | 17037.12 |
Authors | Bhatt, V.S.,Zeng, D.,Krieger, I.,Sacchettini, J.C.,Cho, J.-H. (deposition date: 2016-02-28, release date: 2016-06-29, Last modification date: 2023-09-27) |
Primary citation | Bhatt, V.S.,Zeng, D.,Krieger, I.,Sacchettini, J.C.,Cho, J.H. Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl. Biophys.J., 110:2630-2641, 2016 Cited by PubMed: 27332121DOI: 10.1016/j.bpj.2016.05.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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