2NPW
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![BU of 2npw by Molmil](/molmil-images/mine/2npw) | Solution Structures of a DNA Dodecamer Duplex with a Cisplatin 1,2-d(GG) Intrastrand Cross-Link | Descriptor: | 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3', Cisplatin | Authors: | Wu, Y, Bhattacharyya, D, Chaney, S, Campbell, S. | Deposit date: | 2006-10-30 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link Biochemistry, 46, 2007
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2NQ1
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![BU of 2nq1 by Molmil](/molmil-images/mine/2nq1) | Solution Structures of a DNA Dodecamer Duplex | Descriptor: | 5'-D(*CP*CP*TP*CP*AP*GP*GP*CP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*GP*CP*CP*TP*GP*AP*GP*G)-3' | Authors: | Bhattacharyya, D, Wu, Y, Chaney, S, Campbell, S. | Deposit date: | 2006-10-30 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link Biochemistry, 46, 2007
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4FSO
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![BU of 4fso by Molmil](/molmil-images/mine/4fso) | |
4FUV
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![BU of 4fuv by Molmil](/molmil-images/mine/4fuv) | Crystal Structure of Acinetobacter baumannii CarO | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SULFATE ION, porin protein associated with imipenem resistance | Authors: | Eren, E, van den Berg, B. | Deposit date: | 2012-06-28 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Outer membrane transport of amino acids and antibiotics by an 8-stranded b-barrel protein To be Published
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5W3U
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![BU of 5w3u by Molmil](/molmil-images/mine/5w3u) | Crystal structure of SsoPox AsB5 mutant (V27A-I76T-Y97W-Y99F-L130P-L226V) | Descriptor: | 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... | Authors: | Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. | Deposit date: | 2017-06-08 | Release date: | 2017-12-20 | Last modified: | 2021-08-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
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4GG6
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![BU of 4gg6 by Molmil](/molmil-images/mine/4gg6) | Protein complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... | Authors: | Broughton, S.E, Theodossis, A, Petersen, J, Reid, H.H, Rossjohn, J. | Deposit date: | 2012-08-06 | Release date: | 2012-10-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease. Immunity, 37, 2012
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5VR8
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![BU of 5vr8 by Molmil](/molmil-images/mine/5vr8) | |
4FRX
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![BU of 4frx by Molmil](/molmil-images/mine/4frx) | |
4FSP
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![BU of 4fsp by Molmil](/molmil-images/mine/4fsp) | |
4FT6
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5VRI
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![BU of 5vri by Molmil](/molmil-images/mine/5vri) | Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - closed form | Descriptor: | 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... | Authors: | Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. | Deposit date: | 2017-05-10 | Release date: | 2017-12-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
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5W4X
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![BU of 5w4x by Molmil](/molmil-images/mine/5w4x) | Truncated hUGDH | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, UDP-glucose 6-dehydrogenase | Authors: | Sennett, N.C, Custer, G.S, Wood, Z.A. | Deposit date: | 2017-06-13 | Release date: | 2017-07-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The entropic force generated by intrinsically disordered segments tunes protein function. Nature, 563, 2018
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4GDJ
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4GFT
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![BU of 4gft by Molmil](/molmil-images/mine/4gft) | Malaria invasion machinery protein-Nanobody complex | Descriptor: | 1,2-ETHANEDIOL, Myosin A tail domain interacting protein, Nanobody | Authors: | Khamrui, S, Turley, S, Pardon, E, Steyaert, J, Verlinde, C, Fan, E, Bergman, L.W, Hol, W.G.J. | Deposit date: | 2012-08-03 | Release date: | 2013-07-03 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody. Mol.Biochem.Parasitol., 190, 2013
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4GG8
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![BU of 4gg8 by Molmil](/molmil-images/mine/4gg8) | Immune Receptor | Descriptor: | T-CELL RECEPTOR, SP3.4 ALPHA CHAIN, SP3.4 BETA CHAIN, ... | Authors: | Broughton, S.E, Theodossis, A, Petersen, J, Reid, H.H, Rossjohn, J. | Deposit date: | 2012-08-06 | Release date: | 2012-10-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease. Immunity, 37, 2012
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5W1W
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![BU of 5w1w by Molmil](/molmil-images/mine/5w1w) | Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex | Descriptor: | Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... | Authors: | Gras, S, Walpole, N, Farenc, C, Rossjohn, J. | Deposit date: | 2017-06-05 | Release date: | 2017-10-04 | Last modified: | 2018-01-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
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5W90
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![BU of 5w90 by Molmil](/molmil-images/mine/5w90) | FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with unknown ligand | Descriptor: | FEZ-1 protein, GLYCEROL, SULFATE ION, ... | Authors: | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | Deposit date: | 2017-06-22 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J. Mol. Biol., 325, 2003
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5WHR
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![BU of 5whr by Molmil](/molmil-images/mine/5whr) | Discovery of a novel and selective IDO-1 inhibitor PF-06840003 and its characterization as a potential clinical candidate. | Descriptor: | (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Greasley, S.E, Kaiser, S.E, Feng, J.L, Stewart, A. | Deposit date: | 2017-07-18 | Release date: | 2017-12-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J. Med. Chem., 60, 2017
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5WIA
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![BU of 5wia by Molmil](/molmil-images/mine/5wia) | Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375 | Descriptor: | TAR DNA-binding protein 43 | Authors: | Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2017-07-18 | Release date: | 2018-04-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.002 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WKD
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![BU of 5wkd by Molmil](/molmil-images/mine/5wkd) | Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 | Descriptor: | TAR DNA-binding protein 43 | Authors: | Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | Deposit date: | 2017-07-25 | Release date: | 2018-04-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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4GEZ
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![BU of 4gez by Molmil](/molmil-images/mine/4gez) | Structure of a neuraminidase-like protein from A/bat/Guatemala/164/2009 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yang, H, Carney, P.J, Donis, R.O, Stevens, J. | Deposit date: | 2012-08-02 | Release date: | 2012-09-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proc.Natl.Acad.Sci.USA, 109, 2012
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5WOR
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4GEY
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![BU of 4gey by Molmil](/molmil-images/mine/4gey) | High pH structure of Pseudomonas putida OprB | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, DECYL-BETA-D-MALTOPYRANOSIDE, PHOSPHATE ION, ... | Authors: | van den Berg, B. | Deposit date: | 2012-08-02 | Release date: | 2012-10-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for outer membrane sugar uptake in pseudomonads. J.Biol.Chem., 287, 2012
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4GK7
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![BU of 4gk7 by Molmil](/molmil-images/mine/4gk7) | yeast 20S proteasome in complex with the Syringolin-Glidobactin chimera | Descriptor: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | Authors: | Groll, M, Stein, M.L, Bachmann, A. | Deposit date: | 2012-08-10 | Release date: | 2012-08-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells. Biochemistry, 51, 2012
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4GFH
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![BU of 4gfh by Molmil](/molmil-images/mine/4gfh) | Topoisomerase II-DNA-AMPPNP complex | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), ... | Authors: | Schmidt, B.H, Osheroff, N, Berger, J.M. | Deposit date: | 2012-08-03 | Release date: | 2012-10-03 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (4.408 Å) | Cite: | Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat.Struct.Mol.Biol., 19, 2012
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