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5IFE
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BU of 5ife by Molmil
Crystal structure of the human SF3b core complex
Descriptor: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ...
Authors:Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V.
Deposit date:2016-02-25
Release date:2016-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Mol.Cell, 64, 2016
6ZVK
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BU of 6zvk by Molmil
The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ...
Authors:Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-07-24
Release date:2020-12-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
7ABF
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BU of 7abf by Molmil
Human pre-Bact-1 spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-07
Release date:2020-12-09
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
6Y5Q
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BU of 6y5q by Molmil
human 17S U2 snRNP
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
Authors:Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H.
Deposit date:2020-02-25
Release date:2020-06-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
6YAM
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BU of 6yam by Molmil
Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6YBD
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BU of 6ybd by Molmil
Structure of a human 48S translational initiation complex - eIF3
Descriptor: 40S ribosomal protein S13, 40S ribosomal protein S14, 40S ribosomal protein S17, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-16
Release date:2020-09-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
5GSU
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BU of 5gsu by Molmil
Crystal structure of nucleosome core particle consisting of human testis-specific histone variants, Th2A and Th2B
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
Authors:Kumarevel, T, Sivaraman, P.
Deposit date:2016-08-17
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
1KHM
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BU of 1khm by Molmil
C-TERMINAL KH DOMAIN OF HNRNP K (KH3)
Descriptor: PROTEIN (HNRNP K)
Authors:Baber, J, Libutti, D, Levens, D, Tjandra, N.
Deposit date:1999-01-07
Release date:2000-01-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High precision solution structure of the C-terminal KH domain of heterogeneous nuclear ribonucleoprotein K, a c-myc transcription factor.
J.Mol.Biol., 289, 1999
1NH3
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BU of 1nh3 by Molmil
Human Topoisomerase I Ara-C Complex
Descriptor: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ...
Authors:Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R.
Deposit date:2002-12-18
Release date:2003-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex
J.Biol.Chem., 278, 2003
1LPQ
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BU of 1lpq by Molmil
Human DNA Topoisomerase I (70 Kda) In Non-Covalent Complex With A 22 Base Pair DNA Duplex Containing an 8-oxoG Lesion
Descriptor: 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*(8OG)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*CP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I
Authors:Lesher, D.T, Pommier, Y, Stewart, L, Redinbo, M.R.
Deposit date:2002-05-08
Release date:2002-08-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:8-Oxoguanine rearranges the active site of human topoisomerase I
Proc.Natl.Acad.Sci.USA, 99, 2002
4MVT
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BU of 4mvt by Molmil
Crystal structure of SUMO E3 Ligase PIAS3
Descriptor: CHLORIDE ION, E3 SUMO-protein ligase PIAS3, UNKNOWN ATOM OR ION, ...
Authors:Dong, A, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2013-09-24
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of SUMO E3 Ligase PIAS3
to be published
2DH9
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BU of 2dh9 by Molmil
Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M
Descriptor: Heterogeneous nuclear ribonucleoprotein M
Authors:Ochi, T, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-23
Release date:2006-09-23
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M
To be Published
4BS2
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BU of 4bs2 by Molmil
NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA
Descriptor: 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3', TAR DNA-BINDING PROTEIN 43
Authors:Lukavsky, P.J, Daujotyte, D, Tollervey, J.R, Ule, J, Stuani, C, Buratti, E, Baralle, F.E, Damberger, F.F, Allain, F.H.T.
Deposit date:2013-06-06
Release date:2013-11-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular Basis of Ug-Rich RNA Recognition by the Human Splicing Factor Tdp-43
Nat.Struct.Mol.Biol., 20, 2013
2DZQ
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BU of 2dzq by Molmil
Solution Structure of RSGI RUH-066, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I repeat domain-containing protein 1
Authors:Doi-Katayama, Y, Hirota, H, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-30
Release date:2007-03-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-066, a GTF2I domain in human cDNA
To be published
8GUJ
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BU of 8guj by Molmil
Bre1-nucleosome complex (Model II)
Descriptor: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
Authors:Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
Deposit date:2022-09-12
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
2DZR
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BU of 2dzr by Molmil
Solution Structure of RSGI RUH-067, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I repeat domain-containing protein 1
Authors:Doi-Katayama, Y, Hirota, H, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-30
Release date:2007-03-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-067, a GTF2I domain in human cDNA
To be published
8GUI
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BU of 8gui by Molmil
Bre1-nucleosome complex (Model I)
Descriptor: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
Authors:Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
Deposit date:2022-09-12
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
8HAL
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BU of 8hal by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAG
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BU of 8hag by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAM
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BU of 8ham by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAH
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BU of 8hah by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAN
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BU of 8han by Molmil
Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3
Descriptor: CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAI
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BU of 8hai by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
8HAJ
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BU of 8haj by Molmil
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution)
Descriptor: DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T.
Deposit date:2022-10-26
Release date:2023-05-17
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023

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