5A1F
Crystal structure of the catalytic domain of PLU1 in complex with N-oxalylglycine.
Summary for 5A1F
Entry DOI | 10.2210/pdb5a1f/pdb |
Descriptor | LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, N-OXALYLGLYCINE, ... (8 entities in total) |
Functional Keywords | oxidoreductase, lysine-specific demethylase 5b |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus : Q9UGL1 |
Total number of polymer chains | 1 |
Total formula weight | 56141.63 |
Authors | Srikannathasan, V.,Johansson, C.,Strain-Damerell, C.,Gileadi, C.,Szykowska, A.,Kupinska, K.,Kopec, J.,Krojer, T.,Steuber, H.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U. (deposition date: 2015-04-29, release date: 2015-05-06, Last modification date: 2024-01-10) |
Primary citation | Johansson, C.,Velupillai, S.,Tumber, A.,Szykowska, A.,Hookway, E.S.,Nowak, R.P.,Strain-Damerell, C.,Gileadi, C.,Philpott, M.,Burgess-Brown, N.,Wu, N.,Kopec, J.,Nuzzi, A.,Steuber, H.,Egner, U.,Badock, V.,Munro, S.,Lathangue, N.B.,Westaway, S.,Brown, J.,Athanasou, N.,Prinjha, R.,Brennan, P.E.,Oppermann, U. Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12:539-, 2016 Cited by PubMed: 27214403DOI: 10.1038/NCHEMBIO.2087 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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