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6A3C
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BU of 6a3c by Molmil
MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
6A3B
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BU of 6a3b by Molmil
MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
5ZPU
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BU of 5zpu by Molmil
LFS829 in complex with CRM1-Ran-RanBP1
Descriptor: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Lei, Y.
Deposit date:2018-04-16
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:To be published
To Be Published
6A38
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BU of 6a38 by Molmil
MVM NS2 NES in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
4LX0
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BU of 4lx0 by Molmil
Crystal structure of Myo5b globular tail domain in complex with active Rab11a
Descriptor: BERYLLIUM TRIFLUORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A.
Deposit date:2013-07-29
Release date:2013-11-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis of myosin V Rab GTPase-dependent cargo recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
2PT7
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BU of 2pt7 by Molmil
Crystal structure of Cag VirB11 (HP0525) and an inhibitory protein (HP1451)
Descriptor: Cag-alfa, Hypothetical protein
Authors:Hare, S, Fischer, W, Williams, R, Terradot, L, Bayliss, R, Haas, R, Waksman, G.
Deposit date:2007-05-08
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase.
Embo J., 26, 2007
2F9M
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BU of 2f9m by Molmil
3D structure of active human Rab11b GTPase
Descriptor: MAGNESIUM ION, NICKEL (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Scapin, S.M.N, Guimaraes, B.G, Zanchin, N.I.T.
Deposit date:2005-12-06
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform.
J.Struct.Biol., 154, 2006
6CQQ
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BU of 6cqq by Molmil
Crystal structure of F24 TCR -DR15-RQ13 peptide complex
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, F24 alpha chain, ...
Authors:Farenc, C, Gras, S, Rossjohn, J.
Deposit date:2018-03-16
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
6X2M
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BU of 6x2m by Molmil
Crystal Structure of unliganded CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-20
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
2HV8
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BU of 2hv8 by Molmil
Crystal structure of GTP-bound Rab11 in complex with FIP3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eathiraj, S, Mishra, A, Prekeris, R, Lambright, D.G.
Deposit date:2006-07-27
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
J.Mol.Biol., 364, 2006
8J8Z
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BU of 8j8z by Molmil
Structure of beta-arrestin1 in complex with D6Rpp
Descriptor: Atypical chemokine receptor 2, Beta-arrestin-1, Fab30 Heavy Chain, ...
Authors:Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K.
Deposit date:2023-05-02
Release date:2023-12-27
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors.
Science, 383, 2024
8J97
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BU of 8j97 by Molmil
Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked)
Descriptor: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ...
Authors:Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K.
Deposit date:2023-05-02
Release date:2023-12-27
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors.
Science, 383, 2024
8JAF
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BU of 8jaf by Molmil
Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local Refine, non-cross linked)
Descriptor: Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
Authors:Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K.
Deposit date:2023-05-05
Release date:2023-12-27
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors.
Science, 383, 2024
4HB4
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BU of 4hb4 by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ
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BU of 4haz by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HAY
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BU of 4hay by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HB3
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BU of 4hb3 by Molmil
Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B
Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HAT
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BU of 4hat by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HAW
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BU of 4haw by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
2GZD
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BU of 2gzd by Molmil
Crystal Structure of Rab11 in Complex with Rab11-FIP2
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab11 family-interacting protein 2, ...
Authors:Khan, A.R.
Deposit date:2006-05-11
Release date:2006-08-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure, 14, 2006
6CPO
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BU of 6cpo by Molmil
Crystal structure of DR15 presenting the RQ13 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Farenc, C, Gras, S, Rossjohn, J.
Deposit date:2018-03-13
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
2GZH
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BU of 2gzh by Molmil
Crystal Structure of Rab11 in Complex with Rab11-Family Interacting Protein 2
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Khan, A.R.
Deposit date:2006-05-11
Release date:2006-08-15
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure, 14, 2006
4GPT
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BU of 4gpt by Molmil
Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-08-21
Release date:2012-09-05
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells.
Leukemia, 27, 2013
2IV8
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BU of 2iv8 by Molmil
beta appendage in complex with b-arrestin peptide
Descriptor: AP-2 COMPLEX SUBUNIT BETA-1, BETA-ARRESTIN-1
Authors:Ford, M.G.J, Schmid, E.M, McMahon, H.T.
Deposit date:2006-06-08
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role of the Ap2 Beta-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly.
Plos Biol., 4, 2006
4HB2
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BU of 4hb2 by Molmil
Crystal structure of CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013

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