2P7Q
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![BU of 2p7q by Molmil](/molmil-images/mine/2p7q) | Crystal structure of E126Q mutant of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes complexed with MN(II) and 1S,2S-dihydroxypropylphosphonic acid | Descriptor: | Glyoxalase family protein, MANGANESE (II) ION, [(1S,2S)-1,2-DIHYDROXYPROPYL]PHOSPHONIC ACID | Authors: | Fillgrove, K.L, Pakhomova, S, Schaab, M, Newcomer, M.E, Armstrong, R.N. | Deposit date: | 2007-03-20 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Mechanism of the Genomically Encoded Fosfomycin Resistance Protein, FosX, from Listeria monocytogenes. Biochemistry, 46, 2007
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2P9J
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![BU of 2p9j by Molmil](/molmil-images/mine/2p9j) | Crystal structure of AQ2171 from Aquifex aeolicus | Descriptor: | Hypothetical protein AQ2171 | Authors: | Yang, H, Chen, L, Agari, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-26 | Release date: | 2007-05-29 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of AQ2171 from Aquifex aeolicus To be Published
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2PA3
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2GIQ
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![BU of 2giq by Molmil](/molmil-images/mine/2giq) | Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-2 inhibitor | Descriptor: | 1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE, RNA-directed RNA polymerase | Authors: | Harris, S.F. | Deposit date: | 2006-03-29 | Release date: | 2007-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus. J.Virol., 80, 2006
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4DVK
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![BU of 4dvk by Molmil](/molmil-images/mine/4dvk) | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 strain NCP-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... | Authors: | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | Deposit date: | 2012-02-23 | Release date: | 2012-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
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2OZE
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![BU of 2oze by Molmil](/molmil-images/mine/2oze) | The Crystal structure of Delta protein of pSM19035 from Streptoccocus pyogenes | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Orf delta', ... | Authors: | Cicek, A, Weihofen, W, Saenger, W. | Deposit date: | 2007-02-26 | Release date: | 2008-03-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation. Nucleic Acids Res., 36, 2008
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2GMC
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![BU of 2gmc by Molmil](/molmil-images/mine/2gmc) | Structure of C12-LF11 bound to the DPC micelles | Descriptor: | LACTOFERRIN-BASED SYNTHETIC PEPTIDE C12-LF11, LAURIC ACID | Authors: | Japelj, B. | Deposit date: | 2006-04-06 | Release date: | 2007-02-13 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | The Acyl Group as the Central Element of the Structural Organization of Antimicrobial Lipopeptide. J.Am.Chem.Soc., 129, 2007
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2GMI
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![BU of 2gmi by Molmil](/molmil-images/mine/2gmi) | Mms2/Ubc13~Ubiquitin | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2 | Authors: | Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M. | Deposit date: | 2006-04-06 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation. Nat.Struct.Mol.Biol., 13, 2006
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2OF5
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![BU of 2of5 by Molmil](/molmil-images/mine/2of5) | Oligomeric Death Domain complex | Descriptor: | Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein | Authors: | Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H. | Deposit date: | 2007-01-02 | Release date: | 2007-04-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex. Cell(Cambridge,Mass.), 128, 2007
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2GS9
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![BU of 2gs9 by Molmil](/molmil-images/mine/2gs9) | Crystal structure of TT1324 from Thermus thermophilis HB8 | Descriptor: | FORMIC ACID, Hypothetical protein TT1324, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Kamitori, S, Abe, A, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Agari, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-25 | Release date: | 2007-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of TT1324 from Thermus thermophilis HB8 To be Published
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2O64
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![BU of 2o64 by Molmil](/molmil-images/mine/2o64) | Crystal structure of Pim1 with Quercetagetin | Descriptor: | 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Holder, S, Zemskova, M, Zhang, C, Tabrizizad, M, Bremer, R, Neidigh, J.W, Lilly, M.B. | Deposit date: | 2006-12-06 | Release date: | 2007-02-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Mol.Cancer Ther., 6, 2007
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4CGS
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![BU of 4cgs by Molmil](/molmil-images/mine/4cgs) | Crystal structure of the N-terminal domain of the PA subunit of Dhori virus polymerase | Descriptor: | GLYCEROL, POLYMERASE SUBUNIT PA | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | Deposit date: | 2013-11-26 | Release date: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014
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4CYQ
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![BU of 4cyq by Molmil](/molmil-images/mine/4cyq) | Leishmania major N-myristoyltransferase in complex with a hybrid inhibitor (compound 45). | Descriptor: | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, N-{2-chloro-5-[(3S,4R)-1-[(3R)-4-(4-chlorophenyl)-3-hydroxybutanoyl]-4-(hydroxymethyl)pyrrolidin-3-yl]phenyl}-2-(4-fluorophenyl)acetamide, ... | Authors: | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | Deposit date: | 2014-04-14 | Release date: | 2014-10-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors. J.Med.Chem., 57, 2014
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2GKT
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2GLU
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![BU of 2glu by Molmil](/molmil-images/mine/2glu) | The crystal structure of YcgJ protein from Bacillus subitilis | Descriptor: | S-ADENOSYLMETHIONINE, SULFATE ION, ycgJ | Authors: | Burke, T, Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-04-05 | Release date: | 2006-04-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | The crystal structure of YcgJ protein from Bacillus subitilis To be Published
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2NXY
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![BU of 2nxy by Molmil](/molmil-images/mine/2nxy) | HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ... | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | Deposit date: | 2006-11-20 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
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2NYV
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![BU of 2nyv by Molmil](/molmil-images/mine/2nyv) | X-ray crystal structure of a phosphoglycolate phosphatase from Aquifex aeolicus | Descriptor: | Phosphoglycolate phosphatase | Authors: | Ciatto, C, Min, T, Gorman, J, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-11-21 | Release date: | 2006-12-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | X-ray crystal structure of a phosphoglycolate phosphatase from Aquifex aeolicus To be Published
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4CPM
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![BU of 4cpm by Molmil](/molmil-images/mine/4cpm) | Structure of the Neuraminidase from the B/Brisbane/60/2008 virus in complex with Oseltamivir | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | Deposit date: | 2014-02-07 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses. J.Infect.Dis., 210, 2014
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4CQ7
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![BU of 4cq7 by Molmil](/molmil-images/mine/4cq7) | The crystal structure of the allene oxide cyclase 2 from Arabidopsis thaliana with bound product - OPDA | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 9S,13R-12-OXOPHYTODIENOIC ACID, ALLENE OXIDE CYCLASE 2, ... | Authors: | Terlecka, B.A, Pollmann, S, Hofmann, E. | Deposit date: | 2014-02-11 | Release date: | 2015-03-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Ligand-Bound Structures of the Aoc2 from A. Thaliana and the Implications for the Catalytic Mechanism To be Published
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2OAP
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4CJB
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![BU of 4cjb by Molmil](/molmil-images/mine/4cjb) | orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, GLYCOSYLTRANSFERASE FAMILY 6 | Authors: | Pham, T, Stinson, B, Thiyagarajan, N, Lizotte-Waniewski, M, Brew, K, Acharya, K.R. | Deposit date: | 2013-12-19 | Release date: | 2014-02-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structures of Complexes of a Metal-Independent Glycosyltransferase Gt6 from Bacteroides Ovatus with Udp-Galnac and its Hydrolysis Products. J.Biol.Chem., 289, 2014
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2OB9
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![BU of 2ob9 by Molmil](/molmil-images/mine/2ob9) | Structure of bacteriophage HK97 tail assembly chaperone | Descriptor: | Tail assembly chaperone | Authors: | McGrath, T.E, Tuite, A, Bona, D, Saridakis, V, Edwards, A.M, Maxwell, K, Chirgadze, N.Y. | Deposit date: | 2006-12-18 | Release date: | 2007-12-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A conserved spiral structure for highly diverged phage tail assembly chaperones. J.Mol.Biol., 425, 2013
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2OBG
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4CPN
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![BU of 4cpn by Molmil](/molmil-images/mine/4cpn) | Structure of the Neuraminidase from the B/Brisbane/60/2008 virus in complex with Zanamivir | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | Deposit date: | 2014-02-08 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses. J.Infect.Dis., 210, 2014
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2ODJ
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![BU of 2odj by Molmil](/molmil-images/mine/2odj) | |