8S9V
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8S9X
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8SSH
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![BU of 8ssh by Molmil](/molmil-images/mine/8ssh) | MtrR from Neisseria gonorrhoeae bound to Ethinyl Estradiol | Descriptor: | Ethinyl estradiol, HTH-type transcriptional regulator MtrR, PHOSPHATE ION | Authors: | Hooks, G.M, Brennan, R.G. | Deposit date: | 2023-05-08 | Release date: | 2024-02-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR. Nat Commun, 15, 2024
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8SY2
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5DX9
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![BU of 5dx9 by Molmil](/molmil-images/mine/5dx9) | Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | Authors: | Miao, Y, Brennan, R.G. | Deposit date: | 2015-09-23 | Release date: | 2016-06-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proc.Natl.Acad.Sci.USA, 113, 2016
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5DXO
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![BU of 5dxo by Molmil](/molmil-images/mine/5dxo) | |
8SY3
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8SJK
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![BU of 8sjk by Molmil](/molmil-images/mine/8sjk) | Pembrolizumab Caffeine crystal | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY HEAVY CHAIN, ANTIBODY LIGHT CHAIN, ... | Authors: | Larpent, P, Codan, L, Bothe, J.R, Stueber, D, Reichert, P, Fischmann, T, Su, Y, Pabit, S, Gupta, S, Iuzzolino, L, Cote, A. | Deposit date: | 2023-04-18 | Release date: | 2024-04-24 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Small-Angle X-ray Scattering as a Powerful Tool for Phase and Crystallinity Assessment of Monoclonal Antibody Crystallites in Support of Batch Crystallization. Mol Pharm., 2024
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5EL8
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8T2N
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![BU of 8t2n by Molmil](/molmil-images/mine/8t2n) | Crystal structure of GABARAP in complex with the LIR of NSs3 | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, Non-structural protein S | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20, 2024
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6IZ2
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8T2M
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![BU of 8t2m by Molmil](/molmil-images/mine/8t2m) | Crystal structure of GABARAP in complex with the LIR of NSs4 | Descriptor: | Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20, 2024
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8T2L
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![BU of 8t2l by Molmil](/molmil-images/mine/8t2l) | Crystal structure of LC3A in complex with the LIR of NSs4 | Descriptor: | Non-structural protein S,Microtubule-associated proteins 1A/1B light chain 3A chimera | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20, 2024
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7L6O
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![BU of 7l6o by Molmil](/molmil-images/mine/7l6o) | Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ... | Authors: | Manne, K, Edwards, R.J, Acharya, P. | Deposit date: | 2020-12-23 | Release date: | 2021-04-14 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
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8PTX
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![BU of 8ptx by Molmil](/molmil-images/mine/8ptx) | Cryo-EM structure of human Elp123 in complex with tRNA, acetyl-CoA, 5'-deoxyadenosine and methionine | Descriptor: | 5'-DEOXYADENOSINE, ACETYL COENZYME *A, Elongator complex protein 1, ... | Authors: | Abbassi, N, Jaciuk, M, Lin, T.-Y, Glatt, S. | Deposit date: | 2023-07-16 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Cryo-EM structures of the human Elongator complex at work. Nat Commun, 15, 2024
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7NCC
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![BU of 7ncc by Molmil](/molmil-images/mine/7ncc) | Crystal structure of fructose-bisphosphate aldolase FBAP from Bacillus methanolicus | Descriptor: | D-MALATE, IMIDAZOLE, PHOSPHATE ION, ... | Authors: | Einsle, O, Zhang, L, Guetle, D, Jacquot, J.P. | Deposit date: | 2021-01-28 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference Front Microbiol, 12, 2021
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7NC7
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![BU of 7nc7 by Molmil](/molmil-images/mine/7nc7) | Crystal structure of fructose-bisphosphate aldolases FBAC from Bacillus methanolicus | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase | Authors: | Einsle, O, Zhang, L, Guetle, D, Jacquot, J.P. | Deposit date: | 2021-01-28 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference Front Microbiol, 12, 2021
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5ELA
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5ELG
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7NDS
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![BU of 7nds by Molmil](/molmil-images/mine/7nds) | Crystal structure of TphC in a closed conformation | Descriptor: | Tripartite tricarboxylate transporter substrate binding protein, terephthalic acid | Authors: | Levy, C. | Deposit date: | 2021-02-02 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of terephthalate recognition by solute binding protein TphC. Nat Commun, 12, 2021
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7NDR
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![BU of 7ndr by Molmil](/molmil-images/mine/7ndr) | Crystal structure of TphC in an open conformation | Descriptor: | 1,2-ETHANEDIOL, Tripartite tricarboxylate transporter substrate binding protein | Authors: | Levy, C. | Deposit date: | 2021-02-02 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis of terephthalate recognition by solute binding protein TphC. Nat Commun, 12, 2021
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7MSJ
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![BU of 7msj by Molmil](/molmil-images/mine/7msj) | The crystal structure of mouse HVEM | Descriptor: | SULFATE ION, Tumor necrosis factor receptor superfamily member 14 | Authors: | Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C. | Deposit date: | 2021-05-11 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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8TCF
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![BU of 8tcf by Molmil](/molmil-images/mine/8tcf) | Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | Deposit date: | 2023-06-30 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
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4LNQ
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8TCG
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![BU of 8tcg by Molmil](/molmil-images/mine/8tcg) | Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... | Authors: | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | Deposit date: | 2023-06-30 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
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