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6V6T
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BU of 6v6t by Molmil
Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
Descriptor: Delta-theraphotoxin-Hm1b
Authors:Chin, Y.K.Y, Chow, C.Y, King, G.F.
Deposit date:2019-12-05
Release date:2020-05-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
2WSW
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BU of 2wsw by Molmil
Crystal Structure of Carnitine Transporter from Proteus mirabilis
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, BCCT FAMILY BETAINE/CARNITINE/CHOLINE TRANSPORTER, GLYCEROL, ...
Authors:Schulze, S, Terwisscha van Scheltinga, A.C, Kuehlbrandt, W.
Deposit date:2009-09-10
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Structural Basis of Na(+)-Independent and Cooperative Substrate/Product Antiport in Cait.
Nature, 467, 2010
5F1G
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BU of 5f1g by Molmil
Crystal structure of AmpC BER adenylylated in the cytoplasm
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Beta-lactamase, ...
Authors:An, Y.J, Kim, M.K, Na, J.H, Cha, S.S.
Deposit date:2015-11-30
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine.
J.Antimicrob.Chemother., 72, 2017
8VPN
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BU of 8vpn by Molmil
Phosphorylated human NCC in complex with indapamide
Descriptor: 4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 3
Authors:Zhao, Y.X, Cao, E.H.
Deposit date:2024-01-16
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases.
Nat Commun, 15, 2024
8VPP
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BU of 8vpp by Molmil
Phosphorylated human NCC in complex with chlorthalidone
Descriptor: 2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide, Solute carrier family 12 member 3
Authors:Zhao, Y.X, Cao, E.H.
Deposit date:2024-01-16
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases.
Nat Commun, 15, 2024
8AFJ
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BU of 8afj by Molmil
tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:van der Linden, P, Engilberge, S, Atta, M, Carpentier, P.
Deposit date:2022-07-18
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock
To Be Published
4ZPX
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BU of 4zpx by Molmil
Crystal structure of Lon ATPase domain from Thermococcus onnurineus NA1
Descriptor: ATP-dependent protease Lon, GLYCEROL
Authors:An, Y.J, Kim, M.I, Na, J.H, Cha, S.S.
Deposit date:2015-05-08
Release date:2016-05-11
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural disparity classifies AAA+ modules of Lon proteases into two distinct clades
To Be Published
7CJ2
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BU of 7cj2 by Molmil
Crystal structure of the Fab antibody complexed with human YKL-40
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 3-like 1 (Cartilage glycoprotein-39), isoform CRA_a, ...
Authors:Choi, S, Na, J.H, Lee, S.J, Woo, J.R, Kim, D.Y, Hong, J.T, Lee, W.K.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Fab antibody complexed with human YKL-40
To Be Published
2AHZ
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BU of 2ahz by Molmil
K+ complex of the NaK Channel
Descriptor: CALCIUM ION, POTASSIUM ION, Potassium channel protein
Authors:Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y.
Deposit date:2005-07-28
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atomic structure of a Na+- and K+-conducting channel.
Nature, 440, 2006
5T4R
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BU of 5t4r by Molmil
NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a
Descriptor: Mu-theraphotoxin-Pn3a
Authors:Rosengren, K.J, Armstrong, D.A, Vetter, I.
Deposit date:2016-08-30
Release date:2017-09-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a.
Sci Rep, 7, 2017
6J55
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BU of 6j55 by Molmil
Crystal structure of an iron superoxide dismutate (FeSOD) from a pathogenic Acanthamoeba castellanii
Descriptor: FE (II) ION, Superoxide dismutase
Authors:Lee, K.H, Dao, T.O, Asaithambi, K, Na, B.K.
Deposit date:2019-01-10
Release date:2019-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.330005 Å)
Cite:Crystal structure of an iron superoxide dismutase from the pathogenic amoeba Acanthamoeba castellanii.
Acta Crystallogr.,Sect.F, 75, 2019
3DH4
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BU of 3dh4 by Molmil
Crystal Structure of Sodium/Sugar symporter with bound Galactose from vibrio parahaemolyticus
Descriptor: ERBIUM (III) ION, SODIUM ION, Sodium/glucose cotransporter, ...
Authors:Abramson, J, Faham, S, Cascio, D.
Deposit date:2008-06-16
Release date:2008-08-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport.
Science, 321, 2008
2YGG
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BU of 2ygg by Molmil
Complex of CaMBR and CaM
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
Authors:Koester, S, Yildiz, O.
Deposit date:2011-04-15
Release date:2011-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:Structure of Human Na+/H+ Exchanger Nhe1 Regulatory Region in Complex with Cam and Ca2+
J.Biol.Chem., 286, 2011
1TTQ
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BU of 1ttq by Molmil
TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) IN THE PRESENCE OF POTASSIUM AT ROOM TEMPERATURE
Descriptor: POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE
Authors:Rhee, S, Parris, K, Ahmed, S, Miles, E.W, Davies, D.R.
Deposit date:1995-10-11
Release date:1996-03-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex.
Biochemistry, 35, 1996
1TTP
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BU of 1ttp by Molmil
TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) IN THE PRESENCE OF CESIUM, ROOM TEMPERATURE
Descriptor: CESIUM ION, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE
Authors:Rhee, S, Parris, K, Ahmed, S, Miles, E.W, Davies, D.R.
Deposit date:1995-10-11
Release date:1996-03-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex.
Biochemistry, 35, 1996
2AFQ
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BU of 2afq by Molmil
1.9 angstrom crystal structure of wild-type human thrombin in the sodium free state
Descriptor: GLYCEROL, Prothrombin
Authors:Johnson, D.J.D, Adams, T.E, Huntington, J.A.
Deposit date:2005-07-26
Release date:2005-11-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of wild-type human thrombin in the Na+-free state
Biochem.J., 392, 2005
2WIT
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BU of 2wit by Molmil
CRYSTAL STRUCTURE OF THE SODIUM-COUPLED GLYCINE BETAINE SYMPORTER BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE
Descriptor: GLYCINE BETAINE TRANSPORTER BETP, TRIMETHYL GLYCINE
Authors:Ressl, S, Terwisscha Van Scheltinga, A.C, Vonrhein, C, Ott, V, Ziegler, C.
Deposit date:2009-05-17
Release date:2009-05-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Molecular Basis of Transport and Regulation in the Na(+)/Betaine Symporter Betp.
Nature, 458, 2009
7X9R
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BU of 7x9r by Molmil
Crystal structure of the antirepressor GmaR
Descriptor: Glycosyl transferase family 2
Authors:Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I.
Deposit date:2022-03-16
Release date:2022-11-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
7X9S
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BU of 7x9s by Molmil
Crystal structure of a complex between the antirepressor GmaR and the transcriptional repressor MogR
Descriptor: GmaR, Motility gene repressor MogR
Authors:Cho, S.Y, Na, H.W, Oh, H.B, Kwak, Y.M, Song, W.S, Park, S.C, Yoon, S.I.
Deposit date:2022-03-16
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
2FMJ
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BU of 2fmj by Molmil
220-loop mutant of streptomyces griseus trypsin
Descriptor: CALCIUM ION, SULFATE ION, Trypsin
Authors:Page, M.J, Di Cera, E.
Deposit date:2006-01-09
Release date:2006-05-23
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conversion of trypsin into a Na(+)-activated enzyme.
Biochemistry, 45, 2006
5X33
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BU of 5x33 by Molmil
Leukotriene B4 receptor BLT1 in complex with BIIL260
Descriptor: 4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide, LTB4 receptor,Lysozyme,LTB4 receptor
Authors:Hori, T, Hirata, K, Yamashita, K, Kawano, Y, Yamamoto, M, Yokoyama, S.
Deposit date:2017-02-03
Release date:2018-01-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Na+-mimicking ligands stabilize the inactive state of leukotriene B4receptor BLT1.
Nat. Chem. Biol., 14, 2018
1HXF
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BU of 1hxf by Molmil
HUMAN THROMBIN COMPLEX WITH HIRUDIN VARIANT
Descriptor: HIRUDIN VARIANT, THROMBIN
Authors:Tulinsky, A, Zhang, E.
Deposit date:1996-09-09
Release date:1997-01-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular environment of the Na+ binding site of thrombin.
Biophys.Chem., 63, 1997
1HXE
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BU of 1hxe by Molmil
SERINE PROTEASE
Descriptor: HIRUDIN VARIANT-1, RUBIDIUM ION, THROMBIN
Authors:Tulinsky, A, Zhang, E.
Deposit date:1995-12-07
Release date:1996-11-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular environment of the Na+ binding site of thrombin.
Biophys.Chem., 63, 1997
3GIN
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BU of 3gin by Molmil
Crystal structure of E454K-CBD1
Descriptor: CALCIUM ION, Sodium/calcium exchanger 1
Authors:Chaptal, V, Mercado-Besserer, G, Abramson, J.
Deposit date:2009-03-05
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and functional analysis of a Ca2+ sensor mutant of the na+/ca2+ exchanger
J.Biol.Chem., 284, 2009
1L4J
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BU of 1l4j by Molmil
Holliday Junction TCGGTACCGA with Na and Ca Binding Sites.
Descriptor: 5'-D(*TP*CP*GP*GP*TP*AP*CP*CP*GP*A)-3', CALCIUM ION, SODIUM ION
Authors:Thorpe, J.H, Gale, B.C, Teixeira, S.C.M, Cardin, C.J.
Deposit date:2002-03-05
Release date:2003-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational and Hydration Effects of Site-selective Sodium, Calcium and Strontium Ion Binding to the DNA Holliday Junction Structure d(TCGGTACCGA)4
J.Mol.Biol., 327, 2003

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