2HHE
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![BU of 2hhe by Molmil](/molmil-images/mine/2hhe) | OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN | Descriptor: | HEMOGLOBIN (DEOXY) (ALPHA CHAIN), HEMOGLOBIN (DEOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gilliland, G.L, Pechik, I, Fronticelli, C, Ji, X. | Deposit date: | 1994-09-29 | Release date: | 1995-01-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Chloride ion independence of the Bohr effect in a mutant human hemoglobin beta (V1M+H2deleted). J.Biol.Chem., 269, 1994
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2HHF
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2HHG
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![BU of 2hhg by Molmil](/molmil-images/mine/2hhg) | Structure of Protein of Unknown Function RPA3614, Possible Tyrosine Phosphatase, from Rhodopseudomonas palustris CGA009 | Descriptor: | Hypothetical protein RPA3614, PHOSPHATE ION, SODIUM ION | Authors: | Binkowski, T.A, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-06-28 | Release date: | 2006-07-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Hypothetical protein RPA3614 from Rhodopseudomonas palustris CGA009 To be published
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2HHH
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![BU of 2hhh by Molmil](/molmil-images/mine/2hhh) | Crystal structure of kasugamycin bound to the 30S ribosomal subunit | Descriptor: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Schluenzen, F. | Deposit date: | 2006-06-28 | Release date: | 2006-09-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat.Struct.Mol.Biol., 13, 2006
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2HHI
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![BU of 2hhi by Molmil](/molmil-images/mine/2hhi) | The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins | Descriptor: | Immunogenic protein MPT64 | Authors: | Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H. | Deposit date: | 2006-06-28 | Release date: | 2006-12-05 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins. J.Mol.Biol., 366, 2007
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2HHJ
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![BU of 2hhj by Molmil](/molmil-images/mine/2hhj) | Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate (15 days) | Descriptor: | (2R)-2,3-diphosphoglyceric acid, 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, ... | Authors: | Wang, Y, Gong, W. | Deposit date: | 2006-06-28 | Release date: | 2006-10-24 | Last modified: | 2016-07-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J.Biol.Chem., 281, 2006
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2HHK
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![BU of 2hhk by Molmil](/molmil-images/mine/2hhk) | Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol | Descriptor: | (1R)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (9S,10S)-9,10-DIBROMOOCTADECANOATE, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, BACTERIOCHLOROPHYLL A, ... | Authors: | Roszak, A.W, Gardiner, A.T, Isaacs, N.W, Cogdell, R.J. | Deposit date: | 2006-06-28 | Release date: | 2007-03-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Brominated Lipids Identify Lipid Binding Sites on the Surface of the Reaction Center from Rhodobacter sphaeroides. Biochemistry, 46, 2007
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2HHL
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![BU of 2hhl by Molmil](/molmil-images/mine/2hhl) | Crystal structure of the human small CTD phosphatase 3 isoform 1 | Descriptor: | 12-TUNGSTOPHOSPHATE, CTD small phosphatase-like protein | Authors: | Malashkevich, V.N, Toro, R, Ramagopal, U, Sauder, J.M, Schwinn, K.D, Thompson, D.A, Rutter, M.E, Dickey, M, Groshong, C, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Powell, A, Boice, A, Gheyi, T, Ozyurt, S, Atwell, S, Wasserman, S.R, Emtage, S, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-06-28 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
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2HHM
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2HHN
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![BU of 2hhn by Molmil](/molmil-images/mine/2hhn) | Cathepsin S in complex with non covalent arylaminoethyl amide. | Descriptor: | Cathepsin S, N-[(1R)-1-[(BENZYLSULFONYL)METHYL]-2-{[(1S)-1-METHYL-2-{[4-(TRIFLUOROMETHOXY)PHENYL]AMINO}ETHYL]AMINO}-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE, SULFATE ION | Authors: | Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K. | Deposit date: | 2006-06-28 | Release date: | 2007-05-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers Bioorg.Med.Chem.Lett., 16, 2006
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2HHO
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![BU of 2hho by Molmil](/molmil-images/mine/2hho) | NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A. | Deposit date: | 2006-06-28 | Release date: | 2006-07-18 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain. J.Biol.Chem., 281, 2006
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2HHP
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![BU of 2hhp by Molmil](/molmil-images/mine/2hhp) | Structure of yeast poly(A) polymerase in a closed conformation. | Descriptor: | CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase | Authors: | Bohm, A, Toth, J. | Deposit date: | 2006-06-28 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase. J.Mol.Biol., 366, 2007
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2HHQ
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![BU of 2hhq by Molmil](/molmil-images/mine/2hhq) | O6-methyl-guanine:T pair in the polymerase-10 basepair position | Descriptor: | 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*AP*TP*GP*A)-3', DNA polymerase I, ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHS
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![BU of 2hhs by Molmil](/molmil-images/mine/2hhs) | O6-methyl:C pair in the polymerase-10 basepair position | Descriptor: | 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*GP*CP*AP*TP*GP*A)-3', DNA polymerase I, ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHT
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![BU of 2hht by Molmil](/molmil-images/mine/2hht) | C:O6-methyl-guanine pair in the polymerase-2 basepair position | Descriptor: | 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*CP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA polymerase I, ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHU
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![BU of 2hhu by Molmil](/molmil-images/mine/2hhu) | C:O6-methyl-guanine in the polymerase postinsertion site (-1 basepair position) | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*CP*C)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*GP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHV
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![BU of 2hhv by Molmil](/molmil-images/mine/2hhv) | T:O6-methyl-guanine in the polymerase-2 basepair position | Descriptor: | 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*TP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHW
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![BU of 2hhw by Molmil](/molmil-images/mine/2hhw) | ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHX
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![BU of 2hhx by Molmil](/molmil-images/mine/2hhx) | O6-methyl-guanine in the polymerase template preinsertion site | Descriptor: | 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', DNA Polymerase I, ... | Authors: | Warren, J.J, Forsberg, L.J, Beese, L.S. | Deposit date: | 2006-06-28 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HHZ
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![BU of 2hhz by Molmil](/molmil-images/mine/2hhz) | |
2HI0
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![BU of 2hi0 by Molmil](/molmil-images/mine/2hi0) | |
2HI1
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![BU of 2hi1 by Molmil](/molmil-images/mine/2hi1) | |
2HI2
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![BU of 2hi2 by Molmil](/molmil-images/mine/2hi2) | Crystal structure of native Neisseria gonorrhoeae Type IV pilin at 2.3 Angstroms Resolution | Descriptor: | Fimbrial protein, HEPTANE-1,2,3-TRIOL, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | Authors: | Craig, L, Arvai, A.S, Tainer, J.A. | Deposit date: | 2006-06-28 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions. Mol.Cell, 23, 2006
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2HI3
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![BU of 2hi3 by Molmil](/molmil-images/mine/2hi3) | Solution structure of the homeodomain-only protein HOP | Descriptor: | Homeodomain-only protein | Authors: | Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W. | Deposit date: | 2006-06-28 | Release date: | 2007-01-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Analysis of the structure and function of the transcriptional coregulator HOP Biochemistry, 45, 2006
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2HI4
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![BU of 2hi4 by Molmil](/molmil-images/mine/2hi4) | Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone | Descriptor: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1A2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sansen, S, Yano, J.K, Reynald, R.L, Schoch, G.S, Stout, C.D, Johnson, E.F. | Deposit date: | 2006-06-29 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2. J.Biol.Chem., 282, 2007
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