PDB: 35439 resultsInfo pagesStatus searchChemie searchBIRD

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8C4X	PAM Protease Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... Authors: Nomme, J, Gavalda, S, Cioci, G, Guicherd, M, Marty, A, Duquesne, S, Ben Khaled, M. Deposit date: 2023-01-05 Release date: 2024-07-17 Last modified: 2024-07-31 Method: X-RAY DIFFRACTION (1.52 Å) Cite: An engineered enzyme embedded into PLA to make self-biodegradable plastic. Nature, 2024
6XXQ	Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with ATP and spectinomycin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... Authors: Kanchugal P, S, Selmer, M. Deposit date: 2020-01-28 Release date: 2020-04-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis. Antimicrob.Agents Chemother., 64, 2020
6XU2	Human karyopherin RanBP5 (isoform-3) Descriptor: Antipain, Importin-5, NICKEL (II) ION Authors: Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T. Deposit date: 2020-01-17 Release date: 2020-04-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.834 Å) Cite: X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
6XZ0	Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with spectinomycin Descriptor: SPECTINOMYCIN, Streptomycin 3''-adenylyltransferase Authors: Kanchugal P, S, Selmer, M. Deposit date: 2020-01-31 Release date: 2020-04-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis. Antimicrob.Agents Chemother., 64, 2020
2XE4	Structure of Oligopeptidase B from Leishmania major Descriptor: ANTIPAIN, CHLORIDE ION, GLYCEROL, ... Authors: McLuskey, K, Paterson, N.G, Bland, N.D, Mottram, J.C, Isaacs, N.W. Deposit date: 2010-05-11 Release date: 2010-10-06 Last modified: 2019-05-15 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Leishmania Major Oligopeptidase B Gives Insight Into the Enzymatic Properties of a Trypanosomatid Virulence Factor. J.Biol.Chem., 285, 2010
6XTE	Human karyopherin RanBP5 (isoform-1) Descriptor: Antipain, CHLORIDE ION, Importin-5, ... Authors: Swale, C, McCarthy, A.A, Ruigrok, R.W.H, Crepin, T. Deposit date: 2020-01-16 Release date: 2020-04-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.27 Å) Cite: X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020
6Z28	Carboxypeptidase T mutant L254N with N-sulfamoyl-L-glutamic acid Descriptor: CALCIUM ION, Carboxypeptidase T, N-sulfamoyl-L-glutamic acid, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: CARBOXYPEPTIDASE T MUTANT L254N WITH WITH N-SULFAMOYL-L-GLUT To Be Published
5AWV	Crystal structure of glycopeptide hexose oxidase DBV29 complexed with teicoplanin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranuronic acid, 8-METHYLNONANOIC ACID, ... Authors: Liu, Y.C, Li, T.L. Deposit date: 2015-07-09 Release date: 2015-08-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds. Nat. Chem. Biol., 7, 2011
8GJ4	A1 Tei: Adenylation domain 1 core construct from teicoplanin biosynthesis Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MbtH-like short polypeptide, ... Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-03-14 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GKM	A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, LEUCINE, ... Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-03-20 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GJP	A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft Descriptor: MbtH-like short polypeptide, Non-ribosomal peptide synthetase Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-03-16 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GIC	A1 Tei + Hpg: Adenylation domain 1 core construct from teicoplanin biosynthesis; 4-hydroxyphenylglycine bound Descriptor: (2S)-AMINO(4-HYDROXYPHENYL)ACETIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MbtH-like short polypeptide, ... Authors: Hansen, M.H, Cryle, M.J. Deposit date: 2023-03-14 Release date: 2023-12-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8HL8	Crystal structrue of MtdL R257K mutant Descriptor: MANGANESE (II) ION, Transglycosylse Authors: Li, F.D, He, C. Deposit date: 2022-11-29 Release date: 2023-03-29 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding. J.Biol.Chem., 299, 2023
5N7Q	CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) IN COMPLEX WITH THE INHIBITOR PEPSTATIN A Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PEPSTATIN A, ... Authors: Brynda, J, Hanova, I, Hobizalova, R, Mares, M. Deposit date: 2017-02-21 Release date: 2017-12-27 Last modified: 2018-06-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite. Cell Chem Biol, 25, 2018
3PRT	Mutant of the Carboxypeptidase T Descriptor: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... Authors: Timofeev, V.I, Akparov, V.K, Grishin, A.M, Kuranova, I.P. Deposit date: 2010-11-30 Release date: 2011-11-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite:
4GM5	Carboxypeptidase T with Sulphamoil Arginine Descriptor: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... Authors: Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2012-08-15 Release date: 2013-08-21 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Carboxypeptidase T with Sulphamoil Arginine To be Published
5T3E	Crystal structure of a nonribosomal peptide synthetase heterocyclization domain. Descriptor: Bacillamide synthetase heterocyclization domain, SULFATE ION Authors: Bloudoff, K, Schmeing, T.M. Deposit date: 2016-08-25 Release date: 2016-11-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.297 Å) Cite: Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1DSR	Peptide antibiotic, NMR, 6 structures Descriptor: (2Z,4E)-7-methylocta-2,4-dienoic acid, RAMOPLANIN A2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Kurz, M, Guba, W. Deposit date: 1996-07-05 Release date: 1997-02-12 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: 3D Structure of Ramoplanin: A Potent Inhibitor of Bacterial Cell Wall Synthesis. Biochemistry, 35, 1996
1JRS	HEMIACETAL COMPLEX BETWEEN LEUPEPTIN AND TRYPSIN Descriptor: CALCIUM ION, Leupeptin, TRYPSIN Authors: Kurinov, I.V, Harrison, R.W. Deposit date: 1996-02-07 Release date: 1996-10-14 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Two crystal structures of the leupeptin-trypsin complex. Protein Sci., 5, 1996
1RPB	SOLUTION STRUCTURE OF RP 71955, A NEW 21 AMINO ACID TRICYCLIC PEPTIDE ACTIVE AGAINST HIV-1 VIRUS Descriptor: Tricyclic peptide RP 71955 Authors: Frechet, D, Guitton, J.D, Herman, F, Faucher, D, Helynck, G, Monegier Du Sorbier, B, Ridoux, J.P, James-Surcouf, E, Vuilhorgne, M. Deposit date: 1993-08-31 Release date: 1994-01-31 Last modified: 2024-06-05 Method: SOLUTION NMR Cite: Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus. Biochemistry, 33, 1994
1RPC	SOLUTION STRUCTURE OF RP 71955, A NEW 21 AMINO ACID TRICYCLIC PEPTIDE ACTIVE AGAINST HIV-1 VIRUS Descriptor: Tricyclic peptide RP 71955 Authors: Frechet, D, Guitton, J.D, Herman, F, Faucher, D, Helynck, G, Monegier Du Sorbier, B, Ridoux, J.P, James-Surcouf, E, Vuilhorgne, M. Deposit date: 1993-08-31 Release date: 1994-01-31 Last modified: 2024-06-05 Method: SOLUTION NMR Cite: Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus. Biochemistry, 33, 1994
1TL9	High resolution crystal structure of calpain I protease core in complex with leupeptin Descriptor: CALCIUM ION, Calpain 1, large [catalytic] subunit, ... Authors: Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. Deposit date: 2004-06-09 Release date: 2004-11-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site J.Mol.Biol., 343, 2004
1FJG	STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. Deposit date: 2000-08-08 Release date: 2000-09-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics Nature, 407, 2000
4BEN	R39-imipenem Acyl-enzyme crystal structure Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... Authors: Van Elder, D, Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2013-03-11 Release date: 2013-03-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structures of R39-Imipenem Acyl-Enzyme. To be Published
4BCT	Crystal structure of kiwi-fruit allergen Act d 2 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, THAUMATIN-LIKE PROTEIN Authors: Pavkov-Keller, T, Bublin, M, Jankovic, M, Breiteneder, H, Keller, W. Deposit date: 2012-10-03 Release date: 2013-10-16 Method: X-RAY DIFFRACTION (0.98 Å) Cite: Crystal Structure of Kiwi-Fruit Allergen Act D 2 To be Published

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