8GKM
A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound
Summary for 8GKM
Entry DOI | 10.2210/pdb8gkm/pdb |
Descriptor | Non-ribosomal peptide synthetase, MbtH-like short polypeptide, LEUCINE, ... (7 entities in total) |
Functional Keywords | amp-binding enzyme, nrps, adenylation domain, ligase |
Biological source | Actinoplanes teichomyceticus More |
Total number of polymer chains | 4 |
Total formula weight | 100015.74 |
Authors | Hansen, M.H.,Cryle, M.J. (deposition date: 2023-03-20, release date: 2023-12-06, Last modification date: 2023-12-13) |
Primary citation | Hansen, M.H.,Adamek, M.,Iftime, D.,Petras, D.,Schuseil, F.,Grond, S.,Stegmann, E.,Cryle, M.J.,Ziemert, N. Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14:7842-7842, 2023 Cited by PubMed: 38030603DOI: 10.1038/s41467-023-43451-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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