8IVW
| Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment | Descriptor: | Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 | Authors: | Geng, Y, Zhai, L. | Deposit date: | 2023-03-29 | Release date: | 2023-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.205 Å) | Cite: | Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
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4RN5
| B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site | Descriptor: | ACETATE ION, GLYCEROL, Neuropilin-1, ... | Authors: | Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. | Deposit date: | 2014-10-23 | Release date: | 2015-10-28 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Conserved water molecules in a ligand-binding site of neuropilin-1 To be Published
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5DQ0
| Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
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5HZ7
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4QDQ
| Physical basis for Nrp2 ligand binding | Descriptor: | GLYCEROL, Neuropilin-2, SULFATE ION | Authors: | Parker, M.W, Vander Kooi, C.W. | Deposit date: | 2014-05-14 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
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5MQG
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5MGK
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5MPZ
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4QDS
| Physical basis for Nrp2 ligand binding | Descriptor: | ACETATE ION, GLYCEROL, Neuropilin-2 | Authors: | Parker, M.W, Vander Kooi, C.W. | Deposit date: | 2014-05-14 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
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5MGG
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5MGJ
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5MGL
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5MGM
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5MQE
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5MQK
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5MGF
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5MGE
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4GZ8
| Mouse Semaphorin 3A, domains Sema-PSI-IG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. | Deposit date: | 2012-09-06 | Release date: | 2012-10-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
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6IXZ
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4RDB
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3LIU
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4K4K
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4JRF
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4JG5
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4Q98
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