PDB: 452 resultsInfo pagesStatus searchChemie searchBIRD

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8GLK	The Type 9 Secretion System dGldL peak II, NucA substrate bound complex Descriptor: Endonuclease I, Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, ... Authors: Deme, J.C, Lea, S.M. Deposit date: 2023-03-22 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: The Type 9 Secretion System caught in the act of transport Nat Microbiol, 2024
8GLN	The Type 9 Secretion System in vivo assembled, RemZ substrate bound complex - conformation 2 Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ... Authors: Deme, J.C, Lea, S.M. Deposit date: 2023-03-22 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: The Type 9 Secretion System caught in the act of transport Nat Microbiol, 2024
8GL8	The Type 9 Secretion System Extended Translocon - SprA-PorV-PPI-RemZ-SkpA-SprE complex Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Periplasmic chaperone for outer membrane proteins Skp, ... Authors: Deme, J.C, Lea, S.M. Deposit date: 2023-03-21 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: The Type 9 Secretion System caught in the act of transport Nat Microbiol, 2024
8GLJ	The Type 9 Secretion System in vitro assembled, FspA-CTD substrate bound complex Descriptor: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Por secretion system C-terminal sorting domain-containing protein, ... Authors: Deme, J.C, Lea, S.M. Deposit date: 2023-03-22 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The Type 9 Secretion System caught in the act of transport Nat Microbiol, 2024
3PRB	Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 Descriptor: FKBP-type peptidyl-prolyl cis-trans isomerase Authors: Martinez-Hackert, E, Hendrickson, W.A. Deposit date: 2010-11-29 Release date: 2011-01-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol., 407, 2011
3PRD	Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26 Descriptor: FKBP-type peptidyl-prolyl cis-trans isomerase Authors: Martinez-Hackert, E, Hendrickson, W.A. Deposit date: 2010-11-29 Release date: 2011-01-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26. J.Mol.Biol., 407, 2011
7U9T	Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.68 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7UA9	Structure of dephosphorylated human RyR2 in the open state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (3.59 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7UA3	Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of Calmodulin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7U9Q	Structure of PKA phosphorylated human RyR2 in the closed state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7U9X	Structure of PKA phosphorylated human RyR2-R2474S in the closed state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7UA4	Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7U9R	Structure of PKA phosphorylated human RyR2 in the open state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (3.69 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7U9Z	Structure of PKA phosphorylated human RyR2-R2474S in the open state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7UA5	Structure of dephosphorylated human RyR2 in the closed state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7UA1	Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of ARM210 Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2022-03-11 Release date: 2022-08-03 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Sci Adv, 8, 2022
7U0T	Crystal Structure of a human Calcineurin A - Calcineurin B fusion bound to FKBP12 and FK-520 Descriptor: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,22R,26aS)-8-ethyl-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Fox III, D, Mayclin, S.J, DeBouver, N.D, Hoy, M.J, Heitman, J, Lorimer, D.D, Horanyi, P.S, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-02-18 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus. Mbio, 13, 2022
7TZC	A drug and ATP binding site in type 1 ryanodine receptor Descriptor: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R. Deposit date: 2022-02-15 Release date: 2022-05-18 Last modified: 2022-07-20 Method: ELECTRON MICROSCOPY (2.45 Å) Cite: A drug and ATP binding site in type 1 ryanodine receptor. Structure, 30, 2022
7VML	Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state) Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
7VMO	Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state) Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
7VMM	Structure of recombinant RyR2 (EGTA dataset, class 1, closed state) Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
7VMQ	Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations Nat Commun, 13, 2022
7VMN	Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
7VMR	Structure of recombinant RyR2 mutant K4593A (EGTA dataset) Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
7VMP	Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state) Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... Authors: Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. Deposit date: 2021-10-09 Release date: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022

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