PDB: 243083 resultsInfo pagesStatus searchChemie searchBIRD

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3FWO	The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin Descriptor: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA Authors: Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A. Deposit date: 2009-01-19 Release date: 2010-01-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.71 Å) Cite: Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin Biotechnologia, 1, 2009
4DZN	A de novo designed Coiled Coil CC-pIL Descriptor: COILED-COIL PEPTIDE CC-PIL Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.59 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
6OHZ	Structure of an uncharacterized protein from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-04-08 Release date: 2019-05-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of an uncharacterized protein from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) to be published
8Z1I	Crystal structure of the isomerase Art22 with ethylene glycol Descriptor: 1,2-ETHANEDIOL, Art22, MANGANESE (II) ION, ... Authors: Guo, L, Li, P.W, Li, D.F, Chen, Y.H. Deposit date: 2024-04-11 Release date: 2025-04-16 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal structure of the isomerase Art22 with ethylene glycol To Be Published
7P3P	Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles Descriptor: Gag polyprotein Authors: Wang, X, Nonin-Lecomte, S, Bouaziz, S. Deposit date: 2021-07-08 Release date: 2023-01-18 Last modified: 2024-03-27 Method: SOLUTION NMR Cite: Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles To Be Published
5YXO	Crystal structure of shaft pilin spaD from Lactobacillus rhamnosus GG in bent conformation Descriptor: Pilus assembly protein Authors: Chaurasia, P, Pratap, S, Palva, A, von Ossowski, I, Krishnan, V. Deposit date: 2017-12-06 Release date: 2018-06-20 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Bent conformation of a backbone pilin N-terminal domain supports a three-stage pilus assembly mechanism. Commun Biol, 1, 2018
9RF2	M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography: ELF5 Descriptor: CHLORIDE ION, Monoacylglycerol lipase, [1-[6-[(4-methoxyphenyl)amino]pyrimidin-4-yl]pyrazol-4-yl]-[(3R)-3-oxidanylpyrrolidin-1-yl]methanone, ... Authors: Riegler-Berket, L, Goedl, L, Oberer, M, Polidori, N. Deposit date: 2025-06-04 Release date: 2025-08-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography To Be Published
9OMU	Crystal structure of E. coli ApaH in complex with Ap4G Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-14 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.55 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9OMW	Crystal structure of E. coli ApaH in complex with Ap4U Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], GLYCEROL, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-14 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.56 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9OP2	Crystal structure of E. coli ApaH in complex with Ap4GUAA Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-16 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.5 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9UO8	Crystal structure of Keap1 in complex with a small molecule inhibitor Descriptor: 4-ethoxy-~{N}-[4-[(4-ethoxyphenyl)sulfonylamino]-3-(2-oxidanylidene-2-pyrrol-1-yl-ethyl)naphthalen-1-yl]benzenesulfonamide, FORMIC ACID, Kelch-like ECH-associated protein 1 Authors: Ishida, H, Osawa, M. Deposit date: 2025-04-25 Release date: 2025-09-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Development of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene-2-acetamide Scaffold, and its Anti-Inflammatory Effects. Chemmedchem, 2025
9OPH	Crystal structure of E. coli ApaH in complex with Up4AG Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-19 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.66 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9OON	Crystal structure of E. coli ApaH in complex with Ap4GU Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-16 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.88 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9NMR	Structure of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset) Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... Authors: Weninger, G, Marks, A.R. Deposit date: 2025-03-04 Release date: 2025-10-08 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: Structural basis for statin-induced skeletal muscle weakness To Be Published
9OPG	Crystal structure of E. coli ApaH in complex with Ap4UG Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bis(5'-nucleosyl)-tetraphosphatase [symmetrical], MAGNESIUM ION, ... Authors: Nuthanakanti, A, Serganov, A. Deposit date: 2025-05-19 Release date: 2025-09-03 Method: X-RAY DIFFRACTION (1.74 Å) Cite: ApaH decaps Np 4 N-capped RNAs in two alternative orientations. Nat.Chem.Biol., 2025
9UDG	Cryo-EM structure of Na+-translocating NADH-ubiquinone oxidoreductase from Vibrio cholerae reduced by NADH, with bound aurachin D-42 Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Aurachin D, CALCIUM ION, ... Authors: Ishikawa-Fukuda, M, Kishikawa, J, Kato, T, Murai, M. Deposit date: 2025-04-06 Release date: 2025-06-25 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The Na + -pumping mechanism driven by redox reactions in the NADH-quinone oxidoreductase from Vibrio cholerae relies on dynamic conformational changes. Biorxiv, 2025
9PLK	Interaction of human CYP3A4 with the drug darifenacin Descriptor: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Sevrioukova, I.F. Deposit date: 2025-07-15 Release date: 2025-09-17 Last modified: 2025-09-24 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Interaction of cytochrome P450 3A4 with cannabinoids and the drug darifenacin. J.Biol.Chem., 2025
5MFM	Designed armadillo repeat protein peptide fusion YIIIM6AII_GS11_(KR)5 Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Importin subunit alpha, ... Authors: Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. Deposit date: 2016-11-18 Release date: 2017-09-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Curvature of designed armadillo repeat proteins allows modular peptide binding. J. Struct. Biol., 201, 2018
2G92	Crystal Structure Analysis of the RNA Dodecamer CGC-(NF2)-AAUUAGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2) Descriptor: 5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*AP*GP*CP*G)-3' Authors: Egli, M, Li, F. Deposit date: 2006-03-04 Release date: 2006-04-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. Acs Chem.Biol., 1, 2006
8D7P	Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide Descriptor: Casein kinase I isoform delta, Period circadian protein peptide Authors: Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. Deposit date: 2022-06-07 Release date: 2023-05-17 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.25 Å) Cite: PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
8ZNA	Myxococcus xanthus RomX Descriptor: 1,2-ETHANEDIOL, RomX Authors: Chakraborty, S, Gayathri, P. Deposit date: 2024-05-26 Release date: 2025-06-04 Method: X-RAY DIFFRACTION (1.888 Å) Cite: RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity To Be Published
5L9L	Crystal structure of the PBP MotA from A. tumefaciens B6 in complex with glucopine Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glucopine, ... Authors: Marty, L, Morera, S. Deposit date: 2016-06-10 Release date: 2016-09-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for High Specificity of Amadori Compound and Mannopine Opine Binding in Bacterial Pathogens. J.Biol.Chem., 291, 2016
1TOB	SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES Descriptor: 1,3-DIAMINO-5,6-DIHYDROXYCYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ... Authors: Jiang, L, Suri, A.K, Fiala, R, Patel, D.J. Deposit date: 1996-12-12 Release date: 1997-06-16 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex. Chem.Biol., 4, 1997
9NMO	Structure of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore) Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... Authors: Weninger, G, Marks, A.R. Deposit date: 2025-03-04 Release date: 2025-10-08 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis for statin-induced skeletal muscle weakness To Be Published
9RCG	Vitamin D receptor complex with a vitamin D receptor agonist/histone deacetylase inhibitor hybrid molecule Descriptor: 4-[4-[3-[5-[(3~{S})-4,4-dimethyl-3-oxidanyl-pentyl]-4-methyl-1,3-thiazol-2-yl]pentan-3-yl]phenoxy]-~{N}-oxidanyl-butanamide, Nuclear receptor coactivator 2, Vitamin D3 receptor A Authors: Rochel, N. Deposit date: 2025-05-28 Release date: 2025-10-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Hyperagonism of a Vitamin D Receptor Agonist/Histone Deacetylase Inhibitor Hybrid Molecule. J.Med.Chem., 2025

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