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8TH9
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BU of 8th9 by Molmil
Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA
Descriptor: DIMETHYL SULFOXIDE, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), ...
Authors:Eckenroth, B.E, Doublie, S.
Deposit date:2023-07-14
Release date:2023-11-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural and biochemical insights into NEIL2's preference for abasic sites.
Nucleic Acids Res., 51, 2023
6EVL
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BU of 6evl by Molmil
Crystal structure of an unlignaded peptide-substrate-binding domain of human type II collagen prolyl 4-hydroxylase
Descriptor: DIMETHYL SULFOXIDE, GLYCINE, Prolyl 4-hydroxylase subunit alpha-2, ...
Authors:Murthy, A.V, Sulu, R, Koski, M.K, Wierenga, R.K.
Deposit date:2017-11-02
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif.
Protein Sci., 27, 2018
6EVP
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BU of 6evp by Molmil
Crystal structure the peptide-substrate-binding domain of human type II collagen prolyl 4-hydroxylase complexed with Pro-Pro-Gly-Pro-Glu-Gly-Pro-Pro-Gly.
Descriptor: DIMETHYL SULFOXIDE, PRO-PRO-GLY-PRO-GLU-GLY-PRO-PRO-GLY, Prolyl 4-hydroxylase subunit alpha-2, ...
Authors:Murthy, A.V, Sulu, R, Koski, M.K, Wierenga, R.K.
Deposit date:2017-11-02
Release date:2018-09-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif.
Protein Sci., 27, 2018
6EVW
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BU of 6evw by Molmil
Cryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Manka, S.W.
Deposit date:2017-11-02
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
4LHT
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BU of 4lht by Molmil
Crystal Structure of P450cin Y81F mutant, crystallized in 3 mM 1,8-cineole
Descriptor: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Madrona, Y, Poulos, T.L.
Deposit date:2013-07-01
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:P450cin active site water: implications for substrate binding and solvent accessibility.
Biochemistry, 52, 2013
8TT7
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BU of 8tt7 by Molmil
NMR Assignments and Structure for the Dimeric Kinesin Neck Domain
Descriptor: Kinesin heavy chain isoform 5C
Authors:Alexandrescu, A.T.
Deposit date:2023-08-12
Release date:2023-11-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR assignments and structure for the dimeric kinesin neck domain.
Biomol.Nmr Assign., 17, 2023
6EXH
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BU of 6exh by Molmil
Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/succinate/(4R)-4-hydroxy-L-lysine
Descriptor: 4-HYDROXY-LYSINE, FE (III) ION, GLYCEROL, ...
Authors:Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K.
Deposit date:2017-11-08
Release date:2018-11-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Sci Rep, 8, 2018
6EYM
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BU of 6eym by Molmil
Neutron crystal structure of perdeuterated galectin-3C in complex with lactose
Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Manzoni, F, Coates, L, Blakeley, M.P, Oksanen, E, Logan, D.T.
Deposit date:2017-11-13
Release date:2018-09-12
Last modified:2024-05-01
Method:NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION
Cite:Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design.
J. Med. Chem., 61, 2018
8TAZ
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BU of 8taz by Molmil
Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors
Descriptor: Angiotensin-converting enzyme, Spike glycoprotein
Authors:Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Liang, B.
Deposit date:2023-06-28
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
8T22
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BU of 8t22 by Molmil
Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors at downRBD conformation
Descriptor: Angiotensin-converting enzyme, Spike glycoprotein
Authors:Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Zhou, B, Liang, B.
Deposit date:2023-06-05
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
6EUO
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BU of 6euo by Molmil
Crystal structure of APO Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5
Descriptor: D-MALATE, FE (III) ION, GLYCEROL, ...
Authors:Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K.
Deposit date:2017-10-30
Release date:2018-11-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Sci Rep, 8, 2018
7O9U
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BU of 7o9u by Molmil
Solution structure of oxidized cytochrome c552 from Thioalkalivibrio paradoxus
Descriptor: Cytochrome c552, HEME C
Authors:Britikov, V.V, Britikova, E.V, Altukhov, D.A, Timofeev, V.I, Dergousova, N.I, Rakitina, T.V, Tikhonova, T.V, Usanov, S.A, Popov, V.O, Bocharov, E.V.
Deposit date:2021-04-17
Release date:2021-05-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Unusual Cytochrome c 552 from Thioalkalivibrio paradoxus : Solution NMR Structure and Interaction with Thiocyanate Dehydrogenase.
Int J Mol Sci, 23, 2022
8T20
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BU of 8t20 by Molmil
Cryo-EM structure of mink variant Y453F trimeric spike protein bound to two mink ACE2 receptors
Descriptor: Angiotensin-converting enzyme, Spike glycoprotein
Authors:Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Zhou, B, Liang, B.
Deposit date:2023-06-05
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
4KXY
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BU of 4kxy by Molmil
Human transketolase in complex with ThDP analogue (R)-2-(1,2-dihydroxyethyl)-3-deaza-ThDP
Descriptor: 1,2-ETHANEDIOL, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[(1R)-1,2-dihydroxyethyl]-3-methylthiophen-2-yl}ethyl trihydrogen diphosphate, CALCIUM ION, ...
Authors:Neumann, P, Luedtke, S, Erixon, K.M, Leeper, F, Kluger, R, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4LLF
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BU of 4llf by Molmil
Crystal structure of Cucumber Necrosis Virus
Descriptor: CALCIUM ION, Capsid protein, ZINC ION
Authors:Smith, T.
Deposit date:2013-07-09
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8891 Å)
Cite:Atomic structure of cucumber necrosis virus and the role of the capsid in vector transmission.
J.Virol., 87, 2013
8TWI
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BU of 8twi by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body
Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-21
Release date:2023-11-01
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
6EVX
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BU of 6evx by Molmil
Cryo-EM structure of GDP.Pi-microtubule rapidly co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2017-11-03
Release date:2018-07-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
8FHW
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BU of 8fhw by Molmil
Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in complex with uridine diphosphate and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE
Authors:Washington, E.J, Brennan, R.G.
Deposit date:2022-12-15
Release date:2023-12-20
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals.
Biorxiv, 2024
8SZZ
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BU of 8szz by Molmil
CryoEM Structure of Computationally Designed Nanocage O32-ZL4
Descriptor: O32-ZL4 Component A, O32-ZL4 Component B, SODIUM ION
Authors:Weidle, C, Borst, A.
Deposit date:2023-05-30
Release date:2023-11-01
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Accurate computational design of three-dimensional protein crystals.
Nat Mater, 22, 2023
6F04
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BU of 6f04 by Molmil
N-acetylglucosamine-2-epimerase
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, N-acetylglucosamine-2-epimerase
Authors:Halsoer, M.J, Rothweiler, U.
Deposit date:2017-11-17
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer.
Acta Crystallogr D Struct Biol, 75, 2019
7OQZ
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BU of 7oqz by Molmil
Cryo-EM structure of human TMEM45A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Transmembrane protein 45A
Authors:Grieben, M, Pike, A.C.W, Evans, A, Shrestha, L, Venkaya, S, Mukhopadhyay, S.M.M, Moreira, T, Chalk, R, MacLean, E.M, Marsden, B.D, Burgess-Brown, N.A, Bountra, C, Carpenter, E.P.
Deposit date:2021-06-04
Release date:2021-06-16
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:CryoEM structure of human TMEM45A
To Be Published
8TWE
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BU of 8twe by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body
Descriptor: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-21
Release date:2023-11-01
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
6F07
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BU of 6f07 by Molmil
CBF3 Core Complex
Descriptor: Centromere DNA-binding protein complex CBF3 subunit B, Suppressor of kinetochore protein 1, ZINC ION
Authors:Leber, V, Singleton, M.R.
Deposit date:2017-11-17
Release date:2017-12-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for assembly of the CBF3 kinetochore complex.
EMBO J., 37, 2018
8TTB
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BU of 8ttb by Molmil
Cryo-EM structure of the PP2A:B55-ARPP19 complex
Descriptor: FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-13
Release date:2023-10-25
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8TFI
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BU of 8tfi by Molmil
tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii
Descriptor: CHLORIDE ION, Probable RNA 2'-phosphotransferase
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2023-07-11
Release date:2023-11-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
Proc.Natl.Acad.Sci.USA, 120, 2023

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