8T20

Cryo-EM structure of mink variant Y453F trimeric spike protein bound to two mink ACE2 receptors

Summary for 8T20

Entry DOI	10.2210/pdb8t20/pdb
EMDB information	40976
Descriptor	Spike glycoprotein, Angiotensin-converting enzyme (2 entities in total)
Functional Keywords	coronavirus, spike, ace2, mink, protein binding, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	5
Total formula weight	599483.33
Authors	Ahn, H.M.,Calderon, B.,Fan, X.,Gao, Y.,Horgan, N.,Zhou, B.,Liang, B. (deposition date: 2023-06-05, release date: 2023-10-25)
Primary citation	Ahn, H.,Calderon, B.M.,Fan, X.,Gao, Y.,Horgan, N.L.,Jiang, N.,Blohm, D.S.,Hossain, J.,Rayyan, N.W.K.,Osman, S.H.,Lin, X.,Currier, M.,Steel, J.,Wentworth, D.E.,Zhou, B.,Liang, B. Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2. J Med Virol, 95:e29163-e29163, 2023 Cited by PubMed: 37842796 DOI: 10.1002/jmv.29163 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.36 Å)

Structure validation