3J6G
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![BU of 3j6g by Molmil](/molmil-images/mine/3j6g) | Minimized average structure of microtubules stabilized by taxol | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | Deposit date: | 2014-02-19 | Release date: | 2014-06-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
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3J7Q
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![BU of 3j7q by Molmil](/molmil-images/mine/3j7q) | Structure of the idle mammalian ribosome-Sec61 complex | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2019-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3WS5
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![BU of 3ws5 by Molmil](/molmil-images/mine/3ws5) | N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-2B) | Descriptor: | Beta-lactamase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. | Deposit date: | 2014-02-28 | Release date: | 2015-03-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
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3J9M
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![BU of 3j9m by Molmil](/molmil-images/mine/3j9m) | Structure of the human mitochondrial ribosome (class 1) | Descriptor: | 12S rRNA, 16S rRNA, E-site tRNA, ... | Authors: | Amunts, A, Brown, A, Toots, J, Scheres, S.H, Ramakrishnan, V. | Deposit date: | 2015-02-08 | Release date: | 2015-04-15 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ribosome. The structure of the human mitochondrial ribosome. Science, 348, 2015
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3WWP
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![BU of 3wwp by Molmil](/molmil-images/mine/3wwp) | S-selective hydroxynitrile lyase from Baliospermum montanum (apo2) | Descriptor: | (S)-hydroxynitrile lyase, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Nakano, S, Dadashipour, M, Asano, Y. | Deposit date: | 2014-06-23 | Release date: | 2014-10-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics Biochim.Biophys.Acta, 1844, 2014
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3JCT
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![BU of 3jct by Molmil](/molmil-images/mine/3jct) | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | Descriptor: | 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | Authors: | Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. | Deposit date: | 2016-03-09 | Release date: | 2016-06-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
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3J9X
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![BU of 3j9x by Molmil](/molmil-images/mine/3j9x) | A Virus that Infects a Hyperthermophile Encapsidates A-Form DNA | Descriptor: | DNA, coat protein | Authors: | DiMaio, F, Yu, X, Rensen, E, Krupovic, M, Prangishvili, D, Egelman, E. | Deposit date: | 2015-03-21 | Release date: | 2015-06-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A virus that infects a hyperthermophile encapsidates A-form DNA. Science, 348, 2015
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3SE9
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![BU of 3se9 by Molmil](/molmil-images/mine/3se9) | Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kwong, P.D, Zhou, T. | Deposit date: | 2011-06-10 | Release date: | 2011-08-10 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
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3K09
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![BU of 3k09 by Molmil](/molmil-images/mine/3k09) | Crystal structure of the phosphorylation-site mutant S431D of the KaiC circadian clock protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION | Authors: | Pattanayek, R, Egli, M, Pattanayek, S. | Deposit date: | 2009-09-24 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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3VRW
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![BU of 3vrw by Molmil](/molmil-images/mine/3vrw) | VDR ligand binding domain in complex with 22S-Butyl-2-methylidene-26,27-dimethyl-19,24-dinor-1alpha,25-dihydroxyvitamin D3 | Descriptor: | (1R,3R,7E,17beta)-17-[(2R,3S)-3-butyl-5-ethyl-5-hydroxyheptan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | Authors: | Yoshimoto, N, Inaba, Y, Itoh, T, Nakabayashi, M, Ito, N, Yamamoto, K. | Deposit date: | 2012-04-16 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Butyl pocket formation in the vitamin d receptor strongly affects the agonistic or antagonistic behavior of ligands J.Med.Chem., 55, 2012
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3JAH
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![BU of 3jah by Molmil](/molmil-images/mine/3jah) | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | Deposit date: | 2015-06-10 | Release date: | 2015-08-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural basis for stop codon recognition in eukaryotes. Nature, 524, 2015
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3JC1
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![BU of 3jc1 by Molmil](/molmil-images/mine/3jc1) | Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer | Descriptor: | Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1) | Authors: | McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A. | Deposit date: | 2015-11-09 | Release date: | 2015-12-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure and membrane remodeling activity of ESCRT-III helical polymers. Science, 350, 2015
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3JCO
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![BU of 3jco by Molmil](/molmil-images/mine/3jco) | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F. | Deposit date: | 2016-01-06 | Release date: | 2016-06-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of an endogenous yeast 26S proteasome reveals two major conformational states. Proc.Natl.Acad.Sci.USA, 113, 2016
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3VRV
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![BU of 3vrv by Molmil](/molmil-images/mine/3vrv) | VDR ligand binding domain in complex with 2-Methylidene-26,27-dimethyl-19,24-dinor-1alpha,25-dihydroxyvitamin D3 | Descriptor: | (1R,3R,7E,17beta)-17-[(2R)-5-ethyl-5-hydroxyheptan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | Authors: | Yoshimoto, N, Inaba, Y, Itoh, T, Nakabayashi, M, Ito, N, Yamamoto, K. | Deposit date: | 2012-04-14 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Butyl pocket formation in the vitamin d receptor strongly affects the agonistic or antagonistic behavior of ligands J.Med.Chem., 55, 2012
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3SHJ
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![BU of 3shj by Molmil](/molmil-images/mine/3shj) | Proteasome in complex with hydroxyurea derivative HU10 | Descriptor: | 1-hydroxy-1-[(2R)-4-{3-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yloxy]phenyl}but-3-yn-2-yl]urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, ... | Authors: | Gallastegui, N, Beck, P, Arciniega, M, Hillebrand, S, Huber, R, Groll, M. | Deposit date: | 2011-06-16 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Hydroxyureas as noncovalent proteasome inhibitors. Angew.Chem.Int.Ed.Engl., 51, 2012
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3K4M
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![BU of 3k4m by Molmil](/molmil-images/mine/3k4m) | Pyranose 2-oxidase Y456W mutant in complex with 2FG | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Divne, C, Tan, T.C. | Deposit date: | 2009-10-05 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase. Febs J., 277, 2010
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3S1A
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![BU of 3s1a by Molmil](/molmil-images/mine/3s1a) | Crystal structure of the phosphorylation-site double mutant S431E/T432E of the KaiC circadian clock protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION | Authors: | Pattanayek, R, Williams, D.W, Rossi, G, Weigand, S, Mori, T, Johnson, C.H, Stewart, P.L, Egli, M. | Deposit date: | 2011-05-14 | Release date: | 2011-09-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA. Plos One, 6, 2011
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3S2F
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![BU of 3s2f by Molmil](/molmil-images/mine/3s2f) | Crystal Structure of FurX NADH:Furfural | Descriptor: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHORYLISOPROPANE, ... | Authors: | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | Deposit date: | 2011-05-16 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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3JW7
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![BU of 3jw7 by Molmil](/molmil-images/mine/3jw7) | Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 complexed with Mg and dipeptide L-Ile-L-Tyr | Descriptor: | Dipeptide Epimerase, GLYCEROL, ISOLEUCINE, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Imker, H.J, Sakai, A, Gerlt, J.A, Almo, S.C. | Deposit date: | 2009-09-18 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SL4
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![BU of 3sl4 by Molmil](/molmil-images/mine/3sl4) | Crystal structure of the catalytic domain of PDE4D2 with compound 10D | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL6
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![BU of 3sl6 by Molmil](/molmil-images/mine/3sl6) | Crystal structure of the catalytic domain of PDE4D2 with compound 12c | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3WIP
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![BU of 3wip by Molmil](/molmil-images/mine/3wip) | Crystal structure of acetylcholine bound to Ls-AChBP | Descriptor: | ACETATE ION, ACETYLCHOLINE, Acetylcholine-binding protein, ... | Authors: | Olsen, J.A, Balle, T, Gajhede, M, Ahring, P.K, Kastrup, J.S. | Deposit date: | 2013-09-24 | Release date: | 2014-04-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors Plos One, 9, 2014
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3WL4
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![BU of 3wl4 by Molmil](/molmil-images/mine/3wl4) | N,N'-diacetylchitobiose deacetylase (Se-derivative) from Pyrococcus furiosus | Descriptor: | CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... | Authors: | Nakamura, T, Niiyama, M, Hashimoto, W, Uegaki, K. | Deposit date: | 2013-11-07 | Release date: | 2014-05-07 | Last modified: | 2014-08-20 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N'-diacetylchitobiose deacetylase Febs J., 281, 2014
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3WF0
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![BU of 3wf0 by Molmil](/molmil-images/mine/3wf0) | Crystal structure of human beta-galactosidase in complex with 6S-NBI-DGJ | Descriptor: | (3Z,6S,7R,8S,8aS)-3-(butylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-6,7,8-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Suzuki, H, Ohto, U, Shimizu, T. | Deposit date: | 2013-07-16 | Release date: | 2014-04-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of pharmacological chaperoning for human beta-galactosidase to be published
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3S2G
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![BU of 3s2g by Molmil](/molmil-images/mine/3s2g) | Crystal Structure of FurX NADH+:Furfuryl alcohol I | Descriptor: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | Authors: | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | Deposit date: | 2011-05-16 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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