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5LO2
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BU of 5lo2 by Molmil
Engineering protein stability with atomic precision in a monomeric miniprotein
Descriptor: PPaTyr
Authors:Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
Deposit date:2016-08-08
Release date:2017-05-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
5LO3
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BU of 5lo3 by Molmil
Engineering protein stability with atomic precision in a monomeric miniprotein
Descriptor: PPaOMe
Authors:Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
Deposit date:2016-08-08
Release date:2017-05-17
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
6P78
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BU of 6p78 by Molmil
queuine lyase from Clostridium spiroforme bound to SAM and queuine
Descriptor: 2-amino-5-({[(1S,4S,5S)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, IRON/SULFUR CLUSTER, Queuine lyase, ...
Authors:Almo, S.C, Grove, T.L.
Deposit date:2019-06-05
Release date:2019-09-18
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.726 Å)
Cite:Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.
Proc.Natl.Acad.Sci.USA, 116, 2019
1I9F
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BU of 1i9f by Molmil
STRUCTURAL CHARACTERIZATION OF THE COMPLEX OF THE REV RESPONSE ELEMENT RNA WITH A SELECTED PEPTIDE
Descriptor: REV RESPONSE ELEMENT RNA, RSG-1.2 PEPTIDE
Authors:Zhang, Q, Harada, K, Cho, H.S, Frankel, A, Wemmer, D.E.
Deposit date:2001-03-19
Release date:2001-05-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural characterization of the complex of the Rev response element RNA with a selected peptide.
Chem.Biol., 8, 2001
6CFE
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BU of 6cfe by Molmil
Crystal structure of C2S5: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope
Descriptor: Mutant of Apolipoprotein E3 (APO-E3)
Authors:Zhu, C, Ke, H.M, Swanstrom, R, Dokholyan, N.V.
Deposit date:2018-02-14
Release date:2019-02-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies.
Nat Commun, 10, 2019
8B6N
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BU of 8b6n by Molmil
X-ray structure of the haloalkane dehalogenase HaloTag7 circular permutated at positions 141-156 (cpHaloTagDelta)
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Haloalkane dehalogenase
Authors:Tarnawski, M, Johnsson, K, Hiblot, J.
Deposit date:2022-09-27
Release date:2023-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recording physiological history of cells with chemical labeling.
Science, 383, 2024
8B6P
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BU of 8b6p by Molmil
X-ray structure of the haloalkane dehalogenase HaloTag7 circular permutated at positions 154-156 (cpHaloTag7_154-156)
Descriptor: CHLORIDE ION, Haloalkane dehalogenase
Authors:Tarnawski, M, Johnsson, K, Hiblot, J.
Deposit date:2022-09-27
Release date:2023-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Recording physiological history of cells with chemical labeling.
Science, 383, 2024
6QAM
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BU of 6qam by Molmil
Solution NMR structure of outer membrane protein AlkL
Descriptor: Outer membrane protein AlkL
Authors:Schubeis, T, Andreas, L.B, Pintacuda, G.
Deposit date:2018-12-19
Release date:2020-01-15
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A beta-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL.
Proc.Natl.Acad.Sci.USA, 117, 2020
1GX5
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BU of 1gx5 by Molmil
Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
5EMS
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BU of 5ems by Molmil
Crystal Structure of an iodinated insulin analog
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Lawrence, M.C, Pandyarajan, V, Wan, Z, Weiss, M.A.
Deposit date:2015-11-06
Release date:2016-11-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.
J. Biol. Chem., 291, 2016
1GX6
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BU of 1gx6 by Molmil
Hepatitis C Virus RNA polymerase in complex with UTP and manganese
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE, URIDINE 5'-TRIPHOSPHATE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
2XWH
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BU of 2xwh by Molmil
HCV-J6 NS5B polymerase structure at 1.8 Angstrom
Descriptor: DI(HYDROXYETHYL)ETHER, POLYETHYLENE GLYCOL (N=34), RNA DEPENDENT RNA POLYMERASE
Authors:Scrima, N, Bressanelli, S.
Deposit date:2010-11-03
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
7YH8
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BU of 7yh8 by Molmil
Crystal structure of a heterochiral protein complex
Descriptor: D-Pep-1, L-19437
Authors:Liang, M, Li, S, Wang, T, Liu, L, Lu, P.
Deposit date:2022-07-13
Release date:2023-07-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a heterochiral protein complex
To Be Published
8TW0
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BU of 8tw0 by Molmil
Crystal Structure of a synthetic ABC heterotrimeric Collagen-like Peptide at 1.53 A
Descriptor: Collagen Mimetic Peptide A, Collagen Mimetic Peptide B, Collagen Mimetic Peptide C, ...
Authors:Miller, M.D, Cole, C.C, Xu, W, Walker, D.R, Hulgan, S.A.H, Pogostin, B.H, Swain, J.W.R, Duella, R, Misiura, M, Wang, X, Kolomeisky, A.B, Phillips Jr, G.N, Hartgerink, J.D.
Deposit date:2023-08-18
Release date:2024-05-29
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Heterotrimeric Collagen Helix with High Specificity of Assembly Results in a Rapid Rate of Folding
Nat.Chem., 2024
8TQM
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BU of 8tqm by Molmil
Cryo-EM structure of E3 ubiquitin ligase Doa10 from Saccharomyces cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ERAD-associated E3 ubiquitin-protein ligase DOA10, ...
Authors:Park, E, Itskanov, S.I.
Deposit date:2023-08-07
Release date:2024-03-13
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10.
Nat Commun, 15, 2024
8UBZ
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BU of 8ubz by Molmil
Choline-bound FLVCR1
Descriptor: CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1
Authors:Hite, R.K, Son, Y.
Deposit date:2023-09-25
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
8TQS
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BU of 8tqs by Molmil
Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
Authors:Krishnaswamy, S, Kumar, S.
Deposit date:2023-08-08
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors.
Nat Commun, 15, 2024
8UBX
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BU of 8ubx by Molmil
Ethanolamine-bound FLVCR1
Descriptor: CHOLESTEROL HEMISUCCINATE, ETHANOLAMINE, Heme transporter FLVCR1
Authors:Hite, R.K, Son, Y.
Deposit date:2023-09-25
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
8WOW
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BU of 8wow by Molmil
Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, I160L/G233A mutant
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, UDP-glucose 4-epimerase 2, ...
Authors:Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
Deposit date:2023-10-08
Release date:2024-05-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
8UBY
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BU of 8uby by Molmil
Choline-bound FLVCR1
Descriptor: CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1
Authors:Hite, R.K, Son, Y.
Deposit date:2023-09-25
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
8UC0
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BU of 8uc0 by Molmil
Endogenous ligand bound FLVCR1
Descriptor: CHOLESTEROL HEMISUCCINATE, Heme transporter FLVCR1
Authors:Hite, R.K, Son, Y.
Deposit date:2023-09-25
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
8WOV
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BU of 8wov by Molmil
Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, G233A mutant
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE
Authors:Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
Deposit date:2023-10-07
Release date:2024-05-15
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
8WOP
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BU of 8wop by Molmil
Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, wild-type
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE
Authors:Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
Deposit date:2023-10-07
Release date:2024-05-08
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
8UBW
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BU of 8ubw by Molmil
Choline-bound FLVCR1
Descriptor: CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1
Authors:Hite, R.K, Son, Y.
Deposit date:2023-09-25
Release date:2024-03-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
Nature, 629, 2024
8A1A
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BU of 8a1a by Molmil
Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ...
Authors:Mittl, P.R.E.
Deposit date:2022-06-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022

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