6CFE
Crystal structure of C2S5: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope
Summary for 6CFE
Entry DOI | 10.2210/pdb6cfe/pdb |
Descriptor | Mutant of Apolipoprotein E3 (APO-E3) (2 entities in total) |
Functional Keywords | immunogen, hiv-1, gp120, protein design, mutant of apolipoprotein e3 (apo-e3), lipid transport |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 18643.03 |
Authors | Zhu, C.,Ke, H.M.,Swanstrom, R.,Dokholyan, N.V. (deposition date: 2018-02-14, release date: 2019-02-06, Last modification date: 2023-10-04) |
Primary citation | Zhu, C.,Dukhovlinova, E.,Council, O.,Ping, L.,Faison, E.M.,Prabhu, S.S.,Potter, E.L.,Upton, S.L.,Yin, G.,Fay, J.M.,Kincer, L.P.,Spielvogel, E.,Campbell, S.L.,Benhabbour, S.R.,Ke, H.,Swanstrom, R.,Dokholyan, N.V. Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies. Nat Commun, 10:948-948, 2019 Cited by PubMed: 30814513DOI: 10.1038/s41467-019-08876-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.994 Å) |
Structure validation
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