PDB: 97138 resultsInfo pagesStatus searchChemie searchBIRD

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2YHB	Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains Descriptor: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION Authors: Boland, A, Weichenrieder, O. Deposit date: 2011-04-27 Release date: 2011-06-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein Proc.Natl.Acad.Sci.USA, 108, 2011
3LDH	A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes Descriptor: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID Authors: White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G. Deposit date: 1974-06-06 Release date: 1977-04-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3 Å) Cite: A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes. J.Mol.Biol., 102, 1976
4N3S	Crystal structure of eukaryotic translation initiation factor eIF5B (399-852) from Saccharomyces cerevisiae, apo form Descriptor: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 5B, GLYCEROL Authors: Kuhle, B, Ficner, R. Deposit date: 2013-10-07 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.832 Å) Cite: eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining. Embo J., 33, 2014
4C93	Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha. Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN Authors: Simon, A.C, Pellegrini, L. Deposit date: 2013-10-02 Release date: 2014-04-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.694 Å) Cite: A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014
4N3G	Crystal structure of eukaryotic translation initiation factor eIF5B (870-1116) from Chaetomium thermophilum, domains III and IV Descriptor: CHLORIDE ION, Eukaryotic translation initiation factor 5B-like protein, eIF5B(870-C), ... Authors: Kuhle, B, Ficner, R. Deposit date: 2013-10-07 Release date: 2014-07-09 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.203 Å) Cite: eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining. Embo J., 33, 2014
1C6X	ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. Descriptor: N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE, PROTEIN (PROTEASE) Authors: Munshi, S. Deposit date: 1999-12-28 Release date: 2000-12-28 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease. Acta Crystallogr.,Sect.D, 56, 2000
1C6Y	ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, PROTEIN (PROTEASE) Authors: Munshi, S. Deposit date: 1999-12-28 Release date: 2000-12-28 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease. Acta Crystallogr.,Sect.D, 56, 2000
1IA1	Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE (GW997) Descriptor: 5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Whitlow, M, Howard, A.J, Kuyper, L.F. Deposit date: 2001-03-22 Release date: 2001-04-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH is Displaced by an inhibitor J.Med.Chem., 44, 2001
1IA2	Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW578) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE, DIHYDROFOLATE REDUCTASE, ... Authors: Whitlow, M, Howard, A.J, Kuyper, L.F. Deposit date: 2001-03-22 Release date: 2001-04-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.82 Å) Cite: X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH is Displaced by an inhibitor J.Med.Chem., 44, 2001
6BWG	Crystal structure of native Rv2983 from Mycobacterium tuberculosis Descriptor: 2-phospho-L-lactate guanylyltransferase Authors: Bashiri, G, Jirgis, E.N.M, Baker, E.N. Deposit date: 2017-12-15 Release date: 2018-12-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.99 Å) Cite: A revised biosynthetic pathway for the cofactor F420in prokaryotes. Nat Commun, 10, 2019
7PMK	S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I) Descriptor: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ... Authors: Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. Deposit date: 2021-09-02 Release date: 2021-11-10 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
7PMN	S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II) Descriptor: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ... Authors: Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. Deposit date: 2021-09-02 Release date: 2021-11-10 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
7PLO	H. sapiens replisome-CUL2/LRR1 complex Descriptor: Cell division control protein 45 homolog, Claspin, Cullin-2, ... Authors: Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M. Deposit date: 2021-09-01 Release date: 2021-11-10 Last modified: 2023-10-18 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
6BWH	Crystal structure of Mycoibacterium tuberculosis Rv2983 in complex with PEP Descriptor: 2-phospho-L-lactate guanylyltransferase, MAGNESIUM ION, PHOSPHOENOLPYRUVATE Authors: Bashiri, G, Jirgis, E.N.M, Baker, E.N. Deposit date: 2017-12-15 Release date: 2018-12-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.18 Å) Cite: A revised biosynthetic pathway for the cofactor F420in prokaryotes. Nat Commun, 10, 2019
4C95	Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5 Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5 Authors: Simon, A.C, Pellegrini, L. Deposit date: 2013-10-02 Release date: 2014-04-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.694 Å) Cite: A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014
2YHA	Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains Descriptor: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION Authors: Boland, A, Weichenrieder, O. Deposit date: 2011-04-27 Release date: 2011-06-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein Proc.Natl.Acad.Sci.USA, 108, 2011
1KND	Crystal Structure of 2,3-dihydroxybiphenyl 1,2-dioxygenase Complexed with Catechol under Anaerobic Condition Descriptor: 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, CATECHOL, FE (II) ION, ... Authors: Han, S, Bolin, J.T. Deposit date: 2001-12-18 Release date: 2002-03-27 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol. J.Biol.Chem., 273, 1998
1IA4	Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOLINEDIAMIN (GW2021) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(4-MORPHOLIN-4-YL-PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE, DIHYDROFOLATE REDUCTASE, ... Authors: Whitlow, M, Howard, A.J, Kuyper, L.F. Deposit date: 2001-03-22 Release date: 2001-04-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.85 Å) Cite: X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH is Displaced by an inhibitor J.Med.Chem., 44, 2001
1KNF	Crystal Structure of 2,3-dihydroxybiphenyl 1,2-dioxygenase Complexed with 3-methyl Catechol under Anaerobic Condition Descriptor: 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, 3-METHYLCATECHOL, FE (II) ION, ... Authors: Han, S, Bolin, J.T. Deposit date: 2001-12-18 Release date: 2002-03-27 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol. J.Biol.Chem., 273, 1998
1KMY	Crystal Structure of 2,3-dihydroxybiphenyl 1,2-dioxygenase Complexed with 2,3-dihydroxybiphenyl under Anaerobic Condition Descriptor: 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, BIPHENYL-2,3-DIOL, FE (II) ION, ... Authors: Han, S, Bolin, J.T. Deposit date: 2001-12-17 Release date: 2002-02-20 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol. J.Biol.Chem., 273, 1998
4C8H	Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein. Descriptor: CTF4 Authors: Simon, A.C, Pellegrini, L. Deposit date: 2013-10-01 Release date: 2014-04-30 Last modified: 2014-06-18 Method: X-RAY DIFFRACTION (2.691 Å) Cite: A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome Nature, 510, 2014
1MRQ	Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone Descriptor: Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R. Deposit date: 2002-09-18 Release date: 2003-09-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. J.Mol.Biol., 331, 2003
4C8S	Crystal structure of the C-terminal region of yeast Ctf4 Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN Authors: Simon, A.C, Pellegrini, L. Deposit date: 2013-10-01 Release date: 2014-04-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014
1NQP	Crystal structure of Human hemoglobin E at 1.73 A resolution Descriptor: CYANIDE ION, Hemoglobin alpha chain, Hemoglobin beta chain, ... Authors: Dasgupta, J, Sen, U, Choudhury, D, Dutta, P, Basu, S, Chakrabarti, A, Chakrabarty, A, Dattagupta, J.K. Deposit date: 2003-01-22 Release date: 2004-03-02 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystallization and preliminary X-ray structural Studies of Hemoglobin A2 and Hemoglobin E, isolated from the blood samples of Beta-thalassemic patients Biochem.Biophys.Res.Commun., 303, 2004
1J2B	Crystal Structure Of Archaeosine tRNA-Guanine Transglycosylase Complexed With lambda-form tRNA(Val) Descriptor: Archaeosine tRNA-guanine transglycosylase, MAGNESIUM ION, ZINC ION, ... Authors: Ishitani, R, Nureki, O, Nameki, N, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2002-12-29 Release date: 2003-05-27 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme Cell(Cambridge,Mass.), 113, 2003

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