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5Z50
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BU of 5z50 by Molmil
Crystal structure of PaCysB regulatory domain
Descriptor: Cys regulon transcriptional activator, GLYCEROL, SULFATE ION
Authors:Yang, C, Liang, H, Gan, J.
Deposit date:2018-01-15
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Molecular insights into the master regulator CysB-mediated bacterial virulence in Pseudomonas aeruginosa.
Mol.Microbiol., 111, 2019
8SRU
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BU of 8sru by Molmil
Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a serine acetyltransferase (CysE) derived peptide
Descriptor: Cysteine synthase, Serine acetyltransferase (CysE) derived peptide
Authors:Pederick, J.L, Vandborg, B.C, Bruning, J.B.
Deposit date:2023-05-07
Release date:2024-11-13
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK).
Acs Infect Dis., 11, 2025
8SRT
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BU of 8srt by Molmil
Crystal structure of the O-acetyl-L-serine sulfhydrylase A (CysK) holoenzyme from Staphylococcus aureus NCTC 8325
Descriptor: Cysteine synthase
Authors:Pederick, J.L, Vandborg, B.C, Bruning, J.B.
Deposit date:2023-05-07
Release date:2024-11-13
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK).
Acs Infect Dis., 11, 2025
8SRW
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BU of 8srw by Molmil
Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a modified peptide inhibitor
Descriptor: Cysteine synthase, TYR-MET-NAL-TYR-ILE
Authors:Pederick, J.L, Vandborg, B.C, Bruning, J.B.
Deposit date:2023-05-07
Release date:2024-11-13
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK).
Acs Infect Dis., 11, 2025
8SRV
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BU of 8srv by Molmil
Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a transcriptional repressor (CymR) derived 10 amino acid peptide
Descriptor: Cysteine synthase, Transcriptional repressor (CymR) derived 10 amino acid peptide
Authors:Pederick, J.L, Vandborg, B.C, Bruning, J.B.
Deposit date:2023-05-07
Release date:2024-11-13
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK).
Acs Infect Dis., 11, 2025
8T2C
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BU of 8t2c by Molmil
Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a CymR pentapeptide
Descriptor: Cysteine synthase, TYR-MET-PHE-TYR-ILE
Authors:Pederick, J.L, Bruning, J.B, Vandborg, B.
Deposit date:2023-06-05
Release date:2024-12-18
Last modified:2025-05-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK).
Acs Infect Dis., 11, 2025
6ZS7
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BU of 6zs7 by Molmil
Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with L-cysteine
Descriptor: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine beta-synthase
Authors:Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A.
Deposit date:2020-07-15
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
Comput Struct Biotechnol J, 19, 2021
8JZW
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BU of 8jzw by Molmil
Cystal structure of HP1 in complex with TRIM66 peptide
Descriptor: ASN-SER-GLU-HIS-LYS-ILE-PRO-TYR-VAL-ARG-LEU-GLU-ARG-LEU-LYS-ILE-CYS-ALA, Chromobox homolog 3 (HP1 gamma homolog, Drosophila)
Authors:Shen, S.Y, Li, F.D, Shi, Y.Y.
Deposit date:2023-07-06
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cystal structure of HP1 in complex with TRIM66 peptide
To Be Published
6Z3S
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BU of 6z3s by Molmil
Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with O-Acetylserine
Descriptor: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine beta-synthase
Authors:Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A.
Deposit date:2020-05-21
Release date:2021-06-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.048 Å)
Cite:Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
Comput Struct Biotechnol J, 19, 2021
7QGT
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BU of 7qgt by Molmil
Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with AOAA.
Descriptor: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Hutchin, A, Kopec, J, Majtan, T, Zuhra, K, Szabo, C.
Deposit date:2021-12-10
Release date:2022-10-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:H 2 S biogenesis by cystathionine beta-synthase: mechanism of inhibition by aminooxyacetic acid and unexpected role of serine.
Cell.Mol.Life Sci., 79, 2022
6XYL
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BU of 6xyl by Molmil
Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with L-serine
Descriptor: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine beta-synthase
Authors:Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A.
Deposit date:2020-01-30
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
Comput Struct Biotechnol J, 19, 2021
2W9Q
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BU of 2w9q by Molmil
Crystal Structure of Potato Multicystatin-P212121
Descriptor: MULTICYSTATIN
Authors:Nissen, M.S, Kumar, G.N, Youn, B, Knowles, D.B, Lam, K.S, Ballinger, W.J, Knowles, N.R, Kang, C.
Deposit date:2009-01-28
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of Solanum Tuberosum Multicystatin and its Structural Comparison with Other Cystatins.
Plant Cell, 21, 2009
7RW3
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BU of 7rw3 by Molmil
E. coli cysteine desulfurase SufS N99D
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Gogar, R, Frantom, P.A.
Deposit date:2021-08-19
Release date:2023-01-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
1XT8
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BU of 1xt8 by Molmil
Crystal Structure of Cysteine-Binding Protein from Campylobacter jejuni at 2.0 A Resolution
Descriptor: CYSTEINE, GLYCEROL, putative amino-acid transporter periplasmic solute-binding protein
Authors:Muller, A, Thomas, G.H, Horler, R, Brannigan, J.A, Blagova, E, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe (SPINE)
Deposit date:2004-10-21
Release date:2005-08-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein.
Mol.Microbiol., 57, 2005
2GQN
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BU of 2gqn by Molmil
Cystathionine Beta-Lyase (CBL) from Escherichia Coli in complex with N-Hydrazinocarbonylmethyl-2-Nitro-Benzamide
Descriptor: (5-HYDROXY-6-METHYL-4-((2-(2-(2-NITROBENZAMIDO)ACETYL)HYDRAZINYL)METHYL)PYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Cystathionine beta-lyase
Authors:Summerfield, R, Junop, M.S.
Deposit date:2006-04-21
Release date:2007-03-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibitors of Bacterial Cystathionine beta-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function.
J.Med.Chem., 50, 2007
5TT2
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BU of 5tt2 by Molmil
Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
Descriptor: Cystathionine gamma-lyase, SULFATE ION
Authors:Yan, W, Zhang, Y.
Deposit date:2016-10-31
Release date:2017-10-11
Last modified:2025-04-02
Method:X-RAY DIFFRACTION (2.949 Å)
Cite:Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Biochemistry, 56, 2017
6MRH
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BU of 6mrh by Molmil
E. coli cysteine desulfurase SufS E96A with a cysteine persulfide intermediate
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2018-10-12
Release date:2019-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MRE
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BU of 6mre by Molmil
E. coli cysteine desulfurase SufS R92A with a cysteine persulfide intermediate
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2018-10-12
Release date:2019-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MRI
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BU of 6mri by Molmil
E. coli cysteine desulfurase SufS E250A with a cysteine persulfide intermediate
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2018-10-12
Release date:2019-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MR2
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BU of 6mr2 by Molmil
E. coli cysteine desulfurase SufS with a cysteine persulfide intermediate
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2018-10-11
Release date:2019-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
6MR6
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BU of 6mr6 by Molmil
E. coli cysteine desulfurase SufS H55A with a cysteine persulfide intermediate
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2018-10-11
Release date:2019-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.019 Å)
Cite:Structural Evidence for Dimer-Interface-Driven Regulation of the Type II Cysteine Desulfurase, SufS.
Biochemistry, 58, 2019
1CL2
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BU of 1cl2 by Molmil
CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE
Descriptor: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, CYSTATHIONINE BETA-LYASE
Authors:Clausen, T, Huber, R, Messerschmidt, A.
Deposit date:1997-09-04
Release date:1998-09-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study.
Biochemistry, 36, 1997
3ELN
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BU of 3eln by Molmil
A Putative Fe2+-bound Persulfenate Intermediate in Cysteine Dioxygenase
Descriptor: Cysteine dioxygenase type 1, FE (II) ION, S-HYDROPEROXYCYSTEINE
Authors:Simmons, C.R, Stipanuk, M.H, Karplus, P.A.
Deposit date:2008-09-22
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase.
Biochemistry, 47, 2008
1CS1
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BU of 1cs1 by Molmil
CYSTATHIONINE GAMMA-SYNTHASE (CGS) FROM ESCHERICHIA COLI
Descriptor: 2,4-DIOXO-PENTANEDIOIC ACID, PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE)
Authors:Clausen, T, Messerschmidt, A.
Deposit date:1998-09-23
Release date:1999-09-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution.
EMBO J., 17, 1998
6C2Q
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BU of 6c2q by Molmil
Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of the PLP-L-Serine Intermediate
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Kreinbring, C.A, Tu, Y, Liu, D, Petsko, G.A, Ringe, D.
Deposit date:2018-01-08
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
Biochemistry, 57, 2018

238582

건을2025-07-09부터공개중

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