1CL2

CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE

Summary for 1CL2

Entry DOI	10.2210/pdb1cl2/pdb
Descriptor	CYSTATHIONINE BETA-LYASE, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid (3 entities in total)
Functional Keywords	methionine biosynthesis, plp-dependent enzymes, c-s beta lyase, aminoethoxyvinylglycine, slow-binding inhibition
Biological source	Escherichia coli
Cellular location	Cytoplasm: P06721
Total number of polymer chains	2
Total formula weight	87301.14
Authors	Clausen, T.,Huber, R.,Messerschmidt, A. (deposition date: 1997-09-04, release date: 1998-09-09, Last modification date: 2024-02-07)
Primary citation	Clausen, T.,Huber, R.,Messerschmidt, A.,Pohlenz, H.D.,Laber, B. Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study. Biochemistry, 36:12633-12643, 1997 Cited by PubMed: 9376370 DOI: 10.1021/bi970630m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation