6ZS7

Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with L-cysteine

Summary for 6ZS7

• Entry DOI: 10.2210/pdb6zs7/pdb
• Related: 1JBQ 4LOD
• Descriptor: Cystathionine beta-synthase, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID (2 entities in total)
• Functional Keywords: transulfuration, hydrogen sulfide, l-cysteine, cbs, cytosolic protein
• Biological source: Toxoplasma gondii (strain ATCC 50611 / Me49)
• Total number of polymer chains: 6
• Total formula weight: 337658.96

Authors

Fernandez-Rodriguez, C.,Oyenarte, I.,Conter, C.,Gonzalez-Recio, I.,Quintana, I.,Martinez-Chantar, M.,Astegno, A.,Martinez-Cruz, L.A. (deposition date: 2020-07-15, release date: 2021-07-28, Last modification date: 2024-01-31)

• Primary citation: Fernandez-Rodriguez, C.,Oyenarte, I.,Conter, C.,Gonzalez-Recio, I.,Nunez-Franco, R.,Gil-Pitarch, C.,Quintana, I.,Jimenez-Oses, G.,Dominici, P.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A.; Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .; Comput Struct Biotechnol J, 19:3542-3555, 2021; PubMed: 34194677; DOI: 10.1016/j.csbj.2021.05.052

Experimental method

X-RAY DIFFRACTION (3.5 Å)