3A33
| UbcH5b~Ubiquitin Conjugate | Descriptor: | GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 | Authors: | Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. | Deposit date: | 2009-06-08 | Release date: | 2009-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates Structure, 18, 2010
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2Y9P
| Pex4p-Pex22p mutant II structure | Descriptor: | PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | Authors: | Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M. | Deposit date: | 2011-02-16 | Release date: | 2012-02-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Pex4P-Pex22P Structure To be Published
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4DDG
| Crystal structure of human OTUB1/UbcH5b~Ub/Ub | Descriptor: | Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1 | Authors: | Juang, Y.C, Sanches, M, Sicheri, F. | Deposit date: | 2012-01-18 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2987 Å) | Cite: | OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Mol.Cell, 45, 2012
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2XWU
| CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX | Descriptor: | IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9 | Authors: | Gruenwald, M, Bono, F. | Deposit date: | 2010-11-05 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation. Embo J., 30, 2011
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5ULF
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4DHI
| Structure of C. elegans OTUB1 bound to human UBC13 | Descriptor: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-27 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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4AUQ
| Structure of BIRC7-UbcH5b-Ub complex. | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 D2, ... | Authors: | Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. | Deposit date: | 2012-05-21 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.176 Å) | Cite: | Birc7-E2 Ubiquitin Conjugate Structure Reveals the Mechanism of Ubiquitin Transfer by a Ring Dimer. Nat.Struct.Mol.Biol., 19, 2012
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5TUT
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5ULK
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5VZW
| TRIM23 RING domain in complex with UbcH5-Ub | Descriptor: | E3 ubiquitin-protein ligase TRIM23, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Pornillos, O, Dawidziak, D. | Deposit date: | 2017-05-29 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.278 Å) | Cite: | Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase. Proteins, 85, 2017
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4DHJ
| The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex | Descriptor: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-27 | Release date: | 2012-02-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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4DHZ
| The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub | Descriptor: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | Authors: | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | Deposit date: | 2012-01-30 | Release date: | 2012-02-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
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3UGB
| UbcH5c~Ubiquitin Conjugate | Descriptor: | GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 | Authors: | Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. | Deposit date: | 2011-11-02 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
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2GRO
| Crystal Structure of human RanGAP1-Ubc9-N85Q | Descriptor: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | Authors: | Yunus, A.A, Lima, C.D. | Deposit date: | 2006-04-24 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nat.Struct.Mol.Biol., 13, 2006
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3UIN
| Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 | Descriptor: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | Authors: | Gareau, J.R, Reverter, D, Lima, C.D. | Deposit date: | 2011-11-05 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
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2GRN
| Crystal Structure of human RanGAP1-Ubc9 | Descriptor: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | Authors: | Yunus, A.A, Lima, C.D. | Deposit date: | 2006-04-24 | Release date: | 2006-05-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nat.Struct.Mol.Biol., 13, 2006
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3UIP
| Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | Descriptor: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | Authors: | Gareau, J.R, Reverter, D, Lima, C.D. | Deposit date: | 2011-11-05 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
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3VON
| Crystalstructure of the ubiquitin protease | Descriptor: | Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Sato, Y, Fukai, S. | Deposit date: | 2012-01-30 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. J.Biol.Chem., 287, 2012
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7ZJ3
| Structure of TRIM2 RING domain in complex with UBE2D1~Ub conjugate | Descriptor: | Polyubiquitin-C, Tripartite motif-containing protein 2, Ubiquitin-conjugating enzyme E2 D1, ... | Authors: | Esposito, D, Garza-Garcia, A, Dudley-Fraser, J, Rittinger, K. | Deposit date: | 2022-04-08 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity. Nat Commun, 13, 2022
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6SQO
| Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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4Q5H
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4Q5E
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6SQS
| Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | Descriptor: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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8ATU
| Cryo-EM structure of human BIRC6 | Descriptor: | Baculoviral IAP repeat-containing protein 6, ZINC ION | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | Deposit date: | 2022-08-24 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379, 2023
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8AUK
| Cryo-EM structure of human BIRC6 in complex with HTRA2. | Descriptor: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | Deposit date: | 2022-08-25 | Release date: | 2023-02-15 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379, 2023
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