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1SWO
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BU of 1swo by Molmil
CORE-STREPTAVIDIN MUTANT W120F AT PH 7.5
Descriptor: CORE-STREPTAVIDIN
Authors:Freitag, S, Le Trong, I, Chilkoti, A, Klumb, L.A, Stayton, P.S, Stenkamp, R.E.
Deposit date:1998-01-27
Release date:1999-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
J.Mol.Biol., 279, 1998
1SWR
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BU of 1swr by Molmil
CORE-STREPTAVIDIN MUTANT W120A IN COMPLEX WITH BIOTIN AT PH 7.5
Descriptor: BIOTIN, CORE-STREPTAVIDIN
Authors:Freitag, S, Le Trong, I, Chilkoti, A, Klumb, L.A, Stayton, P.S, Stenkamp, R.E.
Deposit date:1998-01-27
Release date:1999-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
J.Mol.Biol., 279, 1998
1SWN
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BU of 1swn by Molmil
CORE-STREPTAVIDIN MUTANT W108F IN COMPLEX WITH BIOTIN AT PH 7.0
Descriptor: BIOTIN, CORE-STREPTAVIDIN
Authors:Freitag, S, Le Trong, I, Chilkoti, A, Klumb, L.A, Stayton, P.S, Stenkamp, R.E.
Deposit date:1998-01-27
Release date:1999-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
J.Mol.Biol., 279, 1998
1SWP
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BU of 1swp by Molmil
CORE-STREPTAVIDIN MUTANT W120F IN COMPLEX WITH BIOTIN AT PH 7.5
Descriptor: BIOTIN, CORE-STREPTAVIDIN, EPI-BIOTIN
Authors:Freitag, S, Le Trong, I, Chilkoti, A, Klumb, L.A, Stayton, P.S, Stenkamp, R.E.
Deposit date:1998-01-27
Release date:1999-02-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
J.Mol.Biol., 279, 1998
2XCX
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BU of 2xcx by Molmil
Crystal structure of the apoform of the D52N variant of cytosolic 5'- nucleotidase II
Descriptor: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-04-26
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJE
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BU of 2xje by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with uridine 5'-monophosphate and adenosine triphosphate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-07-04
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJC
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BU of 2xjc by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with guanosine monophosphate and diadenosine tetraphosphate
Descriptor: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-07-03
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
1V6X
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BU of 1v6x by Molmil
Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose
Descriptor: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ...
Authors:Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H.
Deposit date:2003-12-04
Release date:2004-04-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
3REX
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BU of 3rex by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with Adenosine monophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, AsnS-like asparaginyl-tRNA synthetase related protein, MAGNESIUM ION
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-05
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3R1B
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BU of 3r1b by Molmil
Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene
Descriptor: (4-tert-butylphenyl)acetaldehyde, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ...
Authors:Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R.
Deposit date:2011-03-09
Release date:2011-05-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity.
Biochemistry, 50, 2011
1SHW
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BU of 1shw by Molmil
EphB2 / EphrinA5 Complex Structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ...
Authors:Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
2B90
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BU of 2b90 by Molmil
Crystal structure of the interleukin-4 variant T13DR85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B91
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BU of 2b91 by Molmil
Crystal structure of the interleukin-4 variant F82DR85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8Z
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BU of 2b8z by Molmil
Crystal structure of the interleukin-4 variant R85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2DYU
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BU of 2dyu by Molmil
Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad
Descriptor: Formamidase
Authors:Wang, W.C, Hung, C.L.
Deposit date:2006-09-18
Release date:2007-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad
J.Biol.Chem., 282, 2007
3RL6
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BU of 3rl6 by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine and Adenosine monophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARAGINE, Archaeal asparagine synthetase A, ...
Authors:Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
Deposit date:2011-04-19
Release date:2011-08-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3C6Q
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BU of 3c6q by Molmil
Apo and ligand-bound form of a thermophilic glucose/xylose binding protein
Descriptor: Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-xylopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2008-02-05
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Open to closed transition of a thermophilic glucose binding protein
To be Published
3BLV
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BU of 3blv by Molmil
Yeast Isocitrate Dehydrogenase with Citrate Bound in the Regulatory Subunits
Descriptor: CITRATE ANION, Isocitrate dehydrogenase [NAD] subunit 1, Isocitrate dehydrogenase [NAD] subunit 2
Authors:Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L.
Deposit date:2007-12-11
Release date:2008-02-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
2L4K
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BU of 2l4k by Molmil
Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139
Descriptor: Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2
Authors:Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A.
Deposit date:2010-10-07
Release date:2010-11-17
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139.
Protein Pept.Lett., 19, 2012
2H7Q
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BU of 2h7q by Molmil
Cytochrome P450cam complexed with imidazole
Descriptor: Cytochrome P450-cam, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Verras, A, Alian, A, Montellano, P.R.
Deposit date:2006-06-02
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation.
Protein Eng.Des.Sel., 19, 2006
2GYI
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BU of 2gyi by Molmil
DESIGN, SYNTHESIS, AND CHARACTERIZATION OF A POTENT XYLOSE ISOMERASE INHIBITOR, D-THREONOHYDROXAMIC ACID, AND HIGH-RESOLUTION X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ENZYME-INHIBITOR COMPLEX
Descriptor: 2,3,4,N-TETRAHYDROXY-BUTYRIMIDIC ACID, MAGNESIUM ION, XYLOSE ISOMERASE
Authors:Allen, K.N, Lavie, A, Petsko, G.A, Ringe, D.
Deposit date:1994-09-01
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design, Synthesis, and Characterization of a Potent Xylose Isomerase Inhibitor, D-Threonohydroxamic Acid, and High-Resolution X-Ray Crystallographic Structure of the Enzyme-Inhibitor Complex
Biochemistry, 34, 1995
2LWR
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BU of 2lwr by Molmil
Solution Structure of RING2 Domain from Parkin
Descriptor: SD01679p, ZINC ION
Authors:Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S.
Deposit date:2012-08-06
Release date:2013-06-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
7U5N
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BU of 7u5n by Molmil
Cryo-EM Structure of Glutamine Synthetase
Descriptor: Glutamine synthetase, MANGANESE (II) ION
Authors:Morgan, C.E, Yu, E.W, Zhang, Z.
Deposit date:2022-03-02
Release date:2022-12-14
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
5Y13
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BU of 5y13 by Molmil
Crystal structure of human FABP4 complexed with ligand 5-((4-bromonaphthalene)-1-sulfonamido)pentanoic acid
Descriptor: 5-[(4-bromanylnaphthalen-1-yl)sulfonylamino]pentanoic acid, Fatty acid-binding protein, adipocyte
Authors:Su, H.X, Liu, Q.F, Xu, Y.C.
Deposit date:2017-07-19
Release date:2018-06-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
1KOK
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BU of 1kok by Molmil
Crystal Structure of Mesopone Cytochrome c Peroxidase (MpCcP)
Descriptor: Cytochrome c Peroxidase, FE(III)-(4-MESOPORPHYRINONE)
Authors:Bhaskar, B, Immoos, C.E, Cohen, M.S, Barrows, T.P, Farmer, P.J, Poulos, T.L.
Deposit date:2001-12-20
Release date:2002-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mesopone cytochrome c peroxidase: functional model of heme oxygenated oxidases.
J.Inorg.Biochem., 91, 2002

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