3CVM
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3CW3
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![BU of 3cw3 by Molmil](/molmil-images/mine/3cw3) | Crystal structure of AIM1g1 | Descriptor: | Absent in melanoma 1 protein, GLYCEROL | Authors: | Aravind, P, Sankaranarayanan, R, Sharma, Y. | Deposit date: | 2008-04-21 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Exploring the limits of sequence and structure in a variant betagamma-crystallin domain of the protein absent in melanoma-1 (AIM1). J.Mol.Biol., 381, 2008
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3CVZ
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3CXP
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![BU of 3cxp by Molmil](/molmil-images/mine/3cxp) | Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 mutant E156A | Descriptor: | CHLORIDE ION, Glucosamine 6-phosphate N-acetyltransferase | Authors: | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | Deposit date: | 2008-04-25 | Release date: | 2008-09-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1 Febs Lett., 582, 2008
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3CXW
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![BU of 3cxw by Molmil](/molmil-images/mine/3cxw) | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I | Descriptor: | (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile, CHLORIDE ION, Pimtide peptide, ... | Authors: | Filippakopoulos, P, Bullock, A, Fedorov, O, Huber, K, Bracher, F, Pike, A.C.W, Roos, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-25 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes J.Med.Chem., 55, 2012
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3CZ3
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![BU of 3cz3 by Molmil](/molmil-images/mine/3cz3) | Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA | Descriptor: | Protein 2b, RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*A)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*G)-3') | Authors: | Ma, J.B, Li, F, Ding, S.W, Patel, D.J. | Deposit date: | 2008-04-27 | Release date: | 2009-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for siRNA Recognition by 2b, a Viral Suppressor of Non-Cell Autonomous RNA Silencing To be Published
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3D0X
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3D1O
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![BU of 3d1o by Molmil](/molmil-images/mine/3d1o) | Structure of the PTP-Like Phytase Expressed by Selenomonas Ruminantium at an Ionic Strength of 300 mM | Descriptor: | CHLORIDE ION, GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase | Authors: | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | Deposit date: | 2008-05-06 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr. Febs J., 275, 2008
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7SML
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![BU of 7sml by Molmil](/molmil-images/mine/7sml) | Crystal Structure of L-GALACTONO-1,4-LACTONE DEHYDROGENASE de Myrciaria dubia | Descriptor: | L-GALACTONO-1,4-LACTONE DEHYDROGENASE | Authors: | Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C. | Deposit date: | 2021-10-26 | Release date: | 2022-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the Smirnoff-Wheeler pathway for vitamin C production in the Amazon fruit Camu-Camu. J.Exp.Bot., 2024
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3D7C
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![BU of 3d7c by Molmil](/molmil-images/mine/3d7c) | Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2 | Descriptor: | General control of amino acid synthesis protein 5-like 2 | Authors: | Filippakopoulos, P, Eswaran, J, Picaud, S, Fedorov, O, Murray, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-21 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3CHW
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3CI9
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![BU of 3ci9 by Molmil](/molmil-images/mine/3ci9) | Crystal Structure of the human HSBP1 | Descriptor: | Heat shock factor-binding protein 1 | Authors: | Liu, X, Xu, L, Liu, Y, Zhu, G, Zhang, X.C, Li, X, Rao, Z. | Deposit date: | 2008-03-11 | Release date: | 2009-01-20 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the hexamer of human heat shock factor binding protein 1 Proteins, 75, 2009
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3CIS
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![BU of 3cis by Molmil](/molmil-images/mine/3cis) | The Crystal Structure of Rv2623 from Mycobacterium tuberculosis | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein | Authors: | Bilder, P, Drumm, J, Mi, K, Chan, J, Almo, S.C. | Deposit date: | 2008-03-11 | Release date: | 2009-03-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Crystal Structure of Rv2623 : a Novel, Tandem-Repeat Universal Stress Protein of Mycobacterium tuberculosis To be Published
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3CEQ
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![BU of 3ceq by Molmil](/molmil-images/mine/3ceq) | The TPR domain of Human Kinesin Light Chain 2 (hKLC2) | Descriptor: | Kinesin light chain 2 | Authors: | Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-29 | Release date: | 2008-08-12 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The TPR domain of Human Kinesin Light Chain 2 (hKLC2) To be Published
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3CKP
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![BU of 3ckp by Molmil](/molmil-images/mine/3ckp) | Crystal structure of BACE-1 in complex with inhibitor | Descriptor: | (4S)-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-1-(3-methoxybenzyl)-2-oxoimidazolidine-4-carboxamide, Beta-secretase 1, CHLORIDE ION | Authors: | Min, K. | Deposit date: | 2008-03-16 | Release date: | 2008-06-03 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives Bioorg.Med.Chem.Lett., 18, 2008
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5PGY
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![BU of 5pgy by Molmil](/molmil-images/mine/5pgy) | CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH 2-[(5R,7S)-6-HYDROXY-2-PHENYLADAMANTAN-2-YL]-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE (BMS-816336) | Descriptor: | 2-[(5R,7S)-6-HYDROXY-2-PHENYLADAMANTAN-2-YL]-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Sheriff, S. | Deposit date: | 2017-02-06 | Release date: | 2017-11-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J. Med. Chem., 60, 2017
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3CPL
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![BU of 3cpl by Molmil](/molmil-images/mine/3cpl) | Crystal Structure of H-2Db in complex with a variant M6A of the NP366 peptide from influenza A virus | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Kedzierska, K, Guillonneau, C, Hatton, L.A, Stockwell, D, Gras, S, Webby, R, Rossjohn, J, Purcell, A.W, Doherty, P.C, Turner, S.J. | Deposit date: | 2008-03-31 | Release date: | 2008-11-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy. Proc.Natl.Acad.Sci.USA, 105, 2008
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3CQF
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![BU of 3cqf by Molmil](/molmil-images/mine/3cqf) | Crystal structure of anthrolysin O (ALO) | Descriptor: | Thiol-activated cytolysin | Authors: | Bourdeau, R.W, Malito, E, Tang, W.J. | Deposit date: | 2008-04-02 | Release date: | 2009-03-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis J.Biol.Chem., 284, 2009
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3CR5
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![BU of 3cr5 by Molmil](/molmil-images/mine/3cr5) | X-ray structure of bovine Pnt-Zn(2+),Ca(2+)-S100B | Descriptor: | 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, CALCIUM ION, Protein S100-B, ... | Authors: | Charpentier, T.H. | Deposit date: | 2008-04-04 | Release date: | 2008-06-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Divalent metal ion complexes of S100B in the absence and presence of pentamidine. J.Mol.Biol., 382, 2008
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3CKC
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![BU of 3ckc by Molmil](/molmil-images/mine/3ckc) | B. thetaiotaomicron SusD | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Koropatkin, N.M, Martens, E.C, Gordon, J.I, Smith, T.J. | Deposit date: | 2008-03-14 | Release date: | 2008-04-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure, 16, 2008
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3CRL
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![BU of 3crl by Molmil](/molmil-images/mine/3crl) | Crystal structure of the PDHK2-L2 complex. | Descriptor: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, MAGNESIUM ION, ... | Authors: | Popov, K.M, Luo, M, Green, T.J, Grigorian, A, Klyuyeva, A, Tuganova, A. | Deposit date: | 2008-04-07 | Release date: | 2008-04-29 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2. J.Biol.Chem., 283, 2008
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3CST
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3CUI
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3CVI
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3D7M
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![BU of 3d7m by Molmil](/molmil-images/mine/3d7m) | Crystal Structure of the G Protein Fast-Exchange Double Mutant I56C/Q333C | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | Authors: | Funk, M.A, Preininger, A.M, Oldham, W.M, Meier, S.M, Hamm, H.E, Iverson, T.M. | Deposit date: | 2008-05-21 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. Biochemistry, 48, 2009
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