3D7M

Crystal Structure of the G Protein Fast-Exchange Double Mutant I56C/Q333C

Summary for 3D7M

Entry DOI	10.2210/pdb3d7m/pdb
Related	1BH2 1GFI 1Y3A 2G83 2HLB
Descriptor	Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ... (5 entities in total)
Functional Keywords	nucleotide binding, allosteric, gtp-binding, lipoprotein, myristate, nucleotide-binding, palmitate, transducer, signaling protein
Biological source	Rattus norvegicus (rat)
Cellular location	Nucleus: P10824
Total number of polymer chains	1
Total formula weight	40934.51
Authors	Funk, M.A.,Preininger, A.M.,Oldham, W.M.,Meier, S.M.,Hamm, H.E.,Iverson, T.M. (deposition date: 2008-05-21, release date: 2009-03-03, Last modification date: 2023-08-30)
Primary citation	Preininger, A.M.,Funk, M.A.,Oldham, W.M.,Meier, S.M.,Johnston, C.A.,Adhikary, S.,Kimple, A.J.,Siderovski, D.P.,Hamm, H.E.,Iverson, T.M. Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. Biochemistry, 48:2630-2642, 2009 Cited by PubMed: 19222191 DOI: 10.1021/bi801853a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation