Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit

Summary for 2G83

DescriptorGuanine nucleotide-binding protein G(i), alpha-1 subunit, KB-1753 phage display peptide, TETRAFLUOROALUMINATE ION, ... (6 entities in total)
Functional Keywordsguanine-nucleotide binding protein, phage display peptide, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) P63096
Total number of polymer chains4
Total molecular weight75553.65
Johnston, C.A.,Ramer, J.K.,Blaesius, R.,Kuhlman, B.,Arshavsky, V.Y.,Siderovski, D.P. (deposition date: 2006-03-01, release date: 2006-10-10, Last modification date: 2011-07-13)
Primary citation
Johnston, C.A.,Lobanova, E.S.,Shavkunov, A.S.,Low, J.,Ramer, J.K.,Blaesius, R.,Fredericks, Z.,Willard, F.S.,Kuhlman, B.,Arshavsky, V.Y.,Siderovski, D.P.
Minimal Determinants for Binding Activated Galpha from the Structure of a Galpha(i1)-Peptide Dimer.
Biochemistry, 45:11390-11400, 2006
PubMed: 16981699 (PDB entries with the same primary citation)
DOI: 10.1021/bi0613832
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.297806.8%21.6%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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