2G83

Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit

Summary for 2G83

DescriptorGuanine nucleotide-binding protein G(i), alpha-1 subunit, KB-1753 phage display peptide, TETRAFLUOROALUMINATE ION, ... (6 entities in total)
Functional Keywordsguanine-nucleotide binding protein, phage display peptide, signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus (By similarity) P63096
Total number of polymer chains4
Total molecular weight75553.65
Authors
Johnston, C.A.,Ramer, J.K.,Blaesius, R.,Kuhlman, B.,Arshavsky, V.Y.,Siderovski, D.P. (deposition date: 2006-03-01, release date: 2006-10-10, Last modification date: 2011-07-13)
Primary citation
Johnston, C.A.,Lobanova, E.S.,Shavkunov, A.S.,Low, J.,Ramer, J.K.,Blaesius, R.,Fredericks, Z.,Willard, F.S.,Kuhlman, B.,Arshavsky, V.Y.,Siderovski, D.P.
Minimal Determinants for Binding Activated Galpha from the Structure of a Galpha(i1)-Peptide Dimer.
Biochemistry, 45:11390-11400, 2006
PubMed: 16981699 (PDB entries with the same primary citation)
DOI: 10.1021/bi0613832
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.297806.8%21.6%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2g83
no rotation
Molmil generated image of 2g83
rotated about x axis by 90°
Molmil generated image of 2g83
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2g83
no rotation
Molmil generated image of 2g83
rotated about x axis by 90°
Molmil generated image of 2g83
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2g83.pdb2.gz [55.47 KB])
Coordinate files for Biological unit (2g83.pdb1.gz [55 KB])