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PDB: 12 results
1E1H
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BU of 1e1h by Molmil
Crystal Structure of recombinant Botulinum Neurotoxin Type A Light Chain, self-inhibiting Zn endopeptidase.
Descriptor: BOTULINUM NEUROTOXIN TYPE A LIGHT CHAIN, ZINC ION
Authors:Knapp, M, Rupp, B.
Deposit date:2000-05-08
Release date:2003-06-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Clostridium Botulinum Neurotoxin Protease in a Product-Bound State: Evidence for Noncanonical Zinc Protease Activity
Proc.Natl.Acad.Sci.USA, 101, 2004
2G7N
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BU of 2g7n by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, SILVER ION, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
6ES1
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BU of 6es1 by Molmil
Crystal structure of the binding domain from botulinum neurotoxin A2 bound to extracellular domain of human receptor SV2C
Descriptor: ACETATE ION, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Gustafsson, R, Masuyer, G, Stenmark, P.
Deposit date:2017-10-19
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
Toxins (Basel), 10, 2018
2G7P
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BU of 2g7p by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
5MOY
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BU of 5moy by Molmil
Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin type A, NONAETHYLENE GLYCOL, ...
Authors:Benoit, R.M, Scharer, M.A.
Deposit date:2016-12-14
Release date:2017-03-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C.
Sci Rep, 7, 2017
2G7Q
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BU of 2g7q by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7K
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BU of 2g7k by Molmil
Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
8JLE
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BU of 8jle by Molmil
Cryo-EM structure of SV2A LD4 in complex with BoNT/A2 Hc in the SV2A-levetiracetam-BoNT/A2 Hc complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ...
Authors:Yamagata, A.
Deposit date:2023-06-02
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
8JLG
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BU of 8jlg by Molmil
Cryo-EM structure of SV2A in complex with BoNT/A2 Hc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ...
Authors:Yamagata, A.
Deposit date:2023-06-02
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
8JS8
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BU of 8js8 by Molmil
Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam
Descriptor: (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yamagata, A.
Deposit date:2023-06-19
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
8JLH
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BU of 8jlh by Molmil
Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam
Descriptor: (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yamagata, A.
Deposit date:2023-06-02
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
8JLF
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BU of 8jlf by Molmil
Cryo-EM structure of SV2A in complex with BoNT/A2 Hc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ...
Authors:Yamagata, A.
Deposit date:2023-06-02
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024

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