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PDB: 7 results

2H62
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BU of 2h62 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
Descriptor: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Mueller, T.D.
Deposit date:2006-05-30
Release date:2007-04-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
5NGV
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BU of 5ngv by Molmil
CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, ORTHORHOMBIC CRYSTAL FORM
Descriptor: Activin receptor type-2B, TETRAETHYLENE GLYCOL, anti-human ActRIIB mAb BYM338 heavy-chain, ...
Authors:Rondeau, J.-M, Lehmann, S.
Deposit date:2017-03-20
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2QLU
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BU of 2qlu by Molmil
Crystal structure of Activin receptor type II kinase domain from human
Descriptor: ADENINE, Activin receptor type IIB, SULFATE ION
Authors:Han, S.
Deposit date:2007-07-13
Release date:2007-11-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Angstrom resolution
Protein Sci., 16, 2007
7MRZ
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BU of 7mrz by Molmil
Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ...
Authors:Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B.
Deposit date:2021-05-10
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022
7OLY
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BU of 7oly by Molmil
Structure of activin A in complex with an ActRIIB-Alk4 fusion reveal insight into activin receptor interactions
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-1B, ...
Authors:Hakansson, M, Rose, N.C, Castonguay, R, Logan, D.T, Krishnan, L.
Deposit date:2021-05-20
Release date:2022-02-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.265 Å)
Cite:Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022
5NHR
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BU of 5nhr by Molmil
CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, CUBIC CRYSTAL FORM
Descriptor: Activin receptor type-2B, Bimagrumab Fv Light-Chain, Bimagrumab Fv heavy-chain
Authors:Rondeau, J.-M.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4FAO
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BU of 4fao by Molmil
Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ...
Authors:Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V.
Deposit date:2012-05-22
Release date:2012-06-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.357 Å)
Cite:Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex.
J.Biol.Chem., 287, 2012

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