1JJO
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1MTP
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![BU of 1mtp by Molmil](/molmil-images/mine/1mtp) | The X-ray crystal structure of a serpin from a thermophilic prokaryote | Descriptor: | Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B | Authors: | Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C. | Deposit date: | 2002-09-21 | Release date: | 2003-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment Structure, 11, 2003
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1KCT
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![BU of 1kct by Molmil](/molmil-images/mine/1kct) | ALPHA1-ANTITRYPSIN | Descriptor: | ALPHA1-ANTITRYPSIN | Authors: | Song, H.K, Suh, S.W. | Deposit date: | 1996-08-06 | Release date: | 1997-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop. FEBS Lett., 377, 1995
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1M93
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2RIW
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![BU of 2riw by Molmil](/molmil-images/mine/2riw) | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | Authors: | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | Deposit date: | 2007-10-12 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
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2WY1
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2VDY
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![BU of 2vdy by Molmil](/molmil-images/mine/2vdy) | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Zhou, A, Wei, Z, Read, R.J. | Deposit date: | 2007-10-13 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
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2V95
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![BU of 2v95 by Molmil](/molmil-images/mine/2v95) | Structure of Corticosteroid-Binding Globulin in complex with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Klieber, M.A, Muller, Y.A. | Deposit date: | 2007-08-21 | Release date: | 2007-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release J.Biol.Chem., 282, 2007
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2VDX
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2WXW
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2WXX
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2WY0
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![BU of 2wy0 by Molmil](/molmil-images/mine/2wy0) | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2WXZ
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2VH4
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![BU of 2vh4 by Molmil](/molmil-images/mine/2vh4) | Structure of a loop C-sheet serpin polymer | Descriptor: | TENGPIN | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins. J.Mol.Biol., 376, 2008
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2WXY
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![BU of 2wxy by Molmil](/molmil-images/mine/2wxy) | Crystal structure of mouse angiotensinogen in the reduced form | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2XN6
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![BU of 2xn6 by Molmil](/molmil-images/mine/2xn6) | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2XN7
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![BU of 2xn7 by Molmil](/molmil-images/mine/2xn7) | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2XN5
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![BU of 2xn5 by Molmil](/molmil-images/mine/2xn5) | Crystal structure of thyroxine-binding globulin complexed with Furosemide | Descriptor: | 1,2-ETHANEDIOL, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, CALCIUM ION, ... | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2XN3
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![BU of 2xn3 by Molmil](/molmil-images/mine/2xn3) | Crystal structure of thyroxine-binding globulin complexed with mefenamic acid | Descriptor: | 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, THYROXINE-BINDING GLOBULIN | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | Deposit date: | 2010-07-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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1A7C
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![BU of 1a7c by Molmil](/molmil-images/mine/1a7c) | HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAPEPTIDE, ... | Authors: | Xue, Y, Inghardt, T, Sjolin, L, Deinum, J. | Deposit date: | 1998-03-12 | Release date: | 1999-03-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure, 6, 1998
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1ATU
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![BU of 1atu by Molmil](/molmil-images/mine/1atu) | UNCLEAVED ALPHA-1-ANTITRYPSIN | Descriptor: | ALPHA-1-ANTITRYPSIN | Authors: | Ryu, S.-E, Choi, H.-J. | Deposit date: | 1997-05-11 | Release date: | 1997-08-20 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A. Structure, 4, 1996
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1ATT
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1BR8
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![BU of 1br8 by Molmil](/molmil-images/mine/1br8) | IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN | Descriptor: | PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) | Authors: | Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. | Deposit date: | 1998-08-26 | Release date: | 1998-09-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin. J.Mol.Biol., 283, 1998
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1ATH
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1B3K
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![BU of 1b3k by Molmil](/molmil-images/mine/1b3k) | Plasminogen activator inhibitor-1 | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | Authors: | Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. | Deposit date: | 1998-12-11 | Release date: | 1999-12-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion. Structure Fold.Des., 7, 1999
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