1S50
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2RC9
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2RC8
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1SD3
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3IJO
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![BU of 3ijo by Molmil](/molmil-images/mine/3ijo) | Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, althiazide | Descriptor: | (3S)-6-chloro-3-[(prop-2-en-1-ylsulfanyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... | Authors: | Ptak, C.P, Ahmed, A.H, Oswald, R.E. | Deposit date: | 2009-08-04 | Release date: | 2009-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
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3ILU
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![BU of 3ilu by Molmil](/molmil-images/mine/3ilu) | Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, hydroflumethiazide | Descriptor: | 6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... | Authors: | Ahmed, A.H, Ptak, C.P, Oswald, R.E. | Deposit date: | 2009-08-07 | Release date: | 2009-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
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7LZ2
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![BU of 7lz2 by Molmil](/molmil-images/mine/7lz2) | Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with methionine | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZI
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7LZH
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![BU of 7lzh by Molmil](/molmil-images/mine/7lzh) | Structure of the glutamate receptor-like channel AtGLR3.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ1
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![BU of 7lz1 by Molmil](/molmil-images/mine/7lz1) | Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with serine | Descriptor: | GLYCEROL, Glutamate receptor 3.4, SERINE, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ0
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![BU of 7lz0 by Molmil](/molmil-images/mine/7lz0) | Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with glutamate | Descriptor: | CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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6U5S
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3KG2
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![BU of 3kg2 by Molmil](/molmil-images/mine/3kg2) | AMPA subtype ionotropic glutamate receptor in complex with competitive antagonist ZK 200775 | Descriptor: | Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sobolevsky, A.I, Rosconi, M.P, Gouaux, E. | Deposit date: | 2009-10-28 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature, 462, 2009
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3KEI
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3KGC
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![BU of 3kgc by Molmil](/molmil-images/mine/3kgc) | Isolated ligand binding domain dimer of GluA2 ionotropic glutamate receptor in complex with glutamate, LY 404187 and ZK 200775 | Descriptor: | GLUTAMIC ACID, Glutamate receptor 2, N-[(2S)-2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide, ... | Authors: | Sobolevsky, A.I, Rosconi, M.P, Gouaux, E. | Deposit date: | 2009-10-28 | Release date: | 2009-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor Nature, 462, 2009
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6UCB
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![BU of 6ucb by Molmil](/molmil-images/mine/6ucb) | GluA2 in complex with its auxiliary subunit CNIH3 - with antagonist ZK200775, LBD, TMD, CNIH3, and lipids | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Glutamate receptor 2, ... | Authors: | Nakagawa, T. | Deposit date: | 2019-09-15 | Release date: | 2019-12-04 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structures of the AMPA receptor in complex with its auxiliary subunit cornichon. Science, 366, 2019
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3LSW
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![BU of 3lsw by Molmil](/molmil-images/mine/3lsw) | Aniracetam bound to the ligand binding domain of GluA3 | Descriptor: | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, GLUTAMIC ACID, GluA2 S1S2 domain, ... | Authors: | Ahmed, A.H, Oswald, R.E. | Deposit date: | 2010-02-13 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
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6UD8
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6U6I
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6USV
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![BU of 6usv by Molmil](/molmil-images/mine/6usv) | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and SDZ 220-040 | Descriptor: | (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, GLYCEROL, GLYCINE, ... | Authors: | Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, h. | Deposit date: | 2019-10-28 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
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6USU
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![BU of 6usu by Molmil](/molmil-images/mine/6usu) | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with L689,560 and glutamate | Descriptor: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ... | Authors: | Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, H. | Deposit date: | 2019-10-28 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.092 Å) | Cite: | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
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7LVT
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![BU of 7lvt by Molmil](/molmil-images/mine/7lvt) | Structure of full-length GluK1 with L-Glu | Descriptor: | Isoform Glur5-2 of Glutamate receptor ionotropic, kainate 1 | Authors: | Meyerson, J.R, Selvakumar, P. | Deposit date: | 2021-02-26 | Release date: | 2021-11-03 | Last modified: | 2021-11-10 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural and compositional diversity in the kainate receptor family. Cell Rep, 37, 2021
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6UZ6
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6UZX
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![BU of 6uzx by Molmil](/molmil-images/mine/6uzx) | Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791 | Descriptor: | (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCEROL, GLYCINE, ... | Authors: | Wang, J.X, Furukawa, H. | Deposit date: | 2019-11-15 | Release date: | 2020-01-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nat Commun, 11, 2020
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6UZG
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