3Q1I
 
 | | Polo-like kinase I Polo-box domain in complex with FMPPPMSpSM phosphopeptide from TCERG1 | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | | Authors: | Sledz, P, Hyvonen, M, Abell, C. | | Deposit date: | 2010-12-17 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Angew.Chem.Int.Ed.Engl., 50, 2011
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4FQG
 | | Crystal structure of the TCERG1 FF4-6 tandem repeat domain | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1 | | Authors: | Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P. | | Deposit date: | 2012-06-25 | | Release date: | 2013-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
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3HFH
 | | Crystal structure of tandem FF domains | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | | Deposit date: | 2009-05-11 | | Release date: | 2009-08-18 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150.
J.Mol.Biol., 393, 2009
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8Q7N
 | | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2023-08-16 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
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7ABF
 | | Human pre-Bact-1 spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-07 | | Release date: | 2020-12-09 | | Last modified: | 2020-12-30 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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8QO9
 | | Cryo-EM structure of a human spliceosomal B complex protomer | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2023-09-28 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (5.29 Å) | | Cite: | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized
spliceosomes
To Be Published
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7ABG
 | | Human pre-Bact-1 spliceosome | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-07 | | Release date: | 2020-12-23 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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2DOE
 | | Solution structure of the third FF domain of human transcription factor CA150 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-28 | | Release date: | 2006-10-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the third FF domain of human transcription factor CA150
To be Published
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2DOF
 | | Solution structure of the fourth FF domain of human transcription factor CA150 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-28 | | Release date: | 2006-10-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the fourth FF domain of human transcription factor CA150
To be Published
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2MWA
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2MWF
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2MWB
 | | FBP28 WW2 mutant W457F | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | | Deposit date: | 2014-11-03 | | Release date: | 2014-12-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2N4U
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2MWD
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2N4R
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2E71
 | | Solution structure of the second FF domain of human transcription factor CA150 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-01-05 | | Release date: | 2007-07-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the second FF domain of human transcription factor CA150
To be Published
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2N4T
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2KIQ
 | | Solution structure of the FF Domain 2 of human transcription elongation factor CA150 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Zeng, J, Boyles, J, Tripathy, C, Yan, A, Zhou, P, Donald, B.R. | | Deposit date: | 2009-05-07 | | Release date: | 2009-07-28 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | High-resolution protein structure determination starting with a global fold calculated from exact solutions to the RDC equations.
J.Biomol.Nmr, 45, 2009
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2NNT
 | | General structural motifs of amyloid protofilaments | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R. | | Deposit date: | 2006-10-24 | | Release date: | 2006-11-14 | | Last modified: | 2023-12-27 | | Method: | SOLID-STATE NMR | | Cite: | General structural motifs of amyloid protofilaments.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2DOD
 | | Solution structure of the first FF domain of human transcription factor CA150 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-28 | | Release date: | 2006-10-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first FF domain of human transcription factor CA150
To be Published
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2KIS
 | | Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T. | | Deposit date: | 2009-05-08 | | Release date: | 2009-09-08 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
J.Mol.Biol., 393, 2009
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2N4V
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2N4S
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2N4W
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2DK7
 | | Solution structure of WW domain in transcription elongation regulator 1 | | Descriptor: | Transcription elongation regulator 1 | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-06 | | Release date: | 2007-04-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of WW domain in transcription elongation regulator 1
To be Published
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