3Q7A
 
 | | Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123 | | Descriptor: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, FARNESYL DIPHOSPHATE, ... | | Authors: | Hast, M.A, Beese, L.S. | | Deposit date: | 2011-01-04 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
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3Q78
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3Q73
 | | Cryptococcus neoformans protein farnesyltransferase, apo enzyme | | Descriptor: | (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Farnesyltransferase, alpha subunit, ... | | Authors: | Hast, M.A, Beese, L.S. | | Deposit date: | 2011-01-04 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
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3Q75
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3Q79
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3Q7F
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3SFX
 | | Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib | | Descriptor: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Cryptococcus neoformans protein farnesyltransferase alpha subunit, ... | | Authors: | Hast, M.A, Beese, L.S. | | Deposit date: | 2011-06-14 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
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3SFY
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