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PDB: 7 件

4MMX
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BU of 4mmx by Molmil
Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
著者van Agthoven, J, Xiong, J, Arnaout, M.A.
登録日2013-09-09
公開日2014-03-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin.
Nat.Struct.Mol.Biol., 21, 2014
4MMY
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BU of 4mmy by Molmil
Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
著者van Agthoven, J, Xiong, J, Arnaout, M.A.
登録日2013-09-09
公開日2014-03-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.183 Å)
主引用文献Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin.
Nat.Struct.Mol.Biol., 21, 2014
4MMZ
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BU of 4mmz by Molmil
Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
著者van Agthoven, J, Xiong, J, Arnaout, M.A.
登録日2013-09-09
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin.
Nat.Struct.Mol.Biol., 21, 2014
6MK0
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BU of 6mk0 by Molmil
Integrin AlphaVBeta3 ectodomain bound to antagonist TDI-4161
分子名称: (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者van Agthoven, J, Arnaout, M.A.
登録日2018-09-24
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Novel Pure alphaVbeta3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations
Acs Pharmacol Transl Sci, 2, 2019
6MSL
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BU of 6msl by Molmil
Integrin AlphaVBeta3 ectodomain bound to EETI-II 2.5D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine Knot Protein 2.5D, ...
著者van Agthoven, J.F, Arnaout, M.A.
登録日2018-10-16
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1.
Structure, 27, 2019
6MSU
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BU of 6msu by Molmil
Integrin alphaVBeta3 in complex with EETI-II 2.5F
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者van Agthoven, J.F, Arnaout, M.A.
登録日2018-10-18
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1.
Structure, 27, 2019
6NAJ
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BU of 6naj by Molmil
Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
著者van Agthoven, J, Arnaout, M.A.
登録日2018-12-05
公開日2019-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-guided design of pure orthosteric inhibitors of alpha IIb beta 3 that prevent thrombosis but preserve hemostasis.
Nat Commun, 11, 2020

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件を2024-07-17に公開中

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