4KNB
| C-Met in complex with OSI ligand | 分子名称: | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | 著者 | Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J. | 登録日 | 2013-05-09 | 公開日 | 2014-04-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases. Bioorg.Med.Chem.Lett., 23, 2013
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2MHM
| Solution structure of cytochrome c Y67H | 分子名称: | Cytochrome c iso-1, HEME C | 著者 | Lan, W.X, Wang, Z.H, Yang, Z.Z, Ying, T.L, Wu, H.M, Tan, X.S, Cao, C.Y, Huang, Z.X. | 登録日 | 2013-11-26 | 公開日 | 2014-10-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase Plos One, 9, 2014
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5A6H
| Synthesis, carbonic anhydrase inhibition and protein X-ray structure of the unusual natural product primary sulfonamide Psammaplin C | 分子名称: | CARBONIC ANHYDRASE 2, DIMETHYL SULFOXIDE, PSAMMAPLIN C, ... | 著者 | Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S. | 登録日 | 2015-06-26 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
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2LIT
| NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states | 分子名称: | Cytochrome c iso-1, HEME C | 著者 | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | 登録日 | 2011-08-31 | 公開日 | 2011-12-07 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
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2LIR
| NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states | 分子名称: | Cytochrome c iso-1, HEME C | 著者 | Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. | 登録日 | 2011-08-31 | 公開日 | 2011-12-07 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
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4WEB
| Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMAMIDE, Mouse Fab Heavy Chain, ... | 著者 | Khan, A.G, Whidby, J, Miller, M.T, Scarborough, H, Zatorski, A.V, Cygan, A, Price, A.A, Yost, S.A, Bohannon, C.D, Jacob, J, Grakoui, A, Marcotrigiano, J. | 登録日 | 2014-09-09 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2. Nature, 509, 2014
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7S3P
| BD2 domain of human BRD3 bound to Physachenolide C | 分子名称: | Bromodomain-containing protein 3, CHLORIDE ION, Physachenolide C | 著者 | Horton, N.C, Chapman, E, Sivinski, J, Zerio, C, Ghadirian, N. | 登録日 | 2021-09-07 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Physachenolide C is a Potent, Selective BET Inhibitor. J.Med.Chem., 66, 2023
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7R8R
| Physachenolide C with Bromodomain (BRD3-BD1) | 分子名称: | Bromodomain-containing protein 3, Physachenolide C | 著者 | Fromme, R, Sivinski, J, Zerio, C, Gunatilaka, A.A.L, Chapman, E. | 登録日 | 2021-06-27 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Physachenolide C is a Potent, Selective BET Inhibitor. J.Med.Chem., 66, 2023
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6ECJ
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1GU6
| Structure of the Periplasmic Cytochrome c Nitrite Reductase from Escherichia coli | 分子名称: | CALCIUM ION, CYTOCHROME C552, GLYCEROL, ... | 著者 | Bamford, V.A, Angove, H.C, Seward, H.E, Thomson, A.J, Cole, J.A, Butt, J.N, Hemmings, A.M, Richardson, D.J. | 登録日 | 2002-01-24 | 公開日 | 2002-03-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Spectroscopy of the Periplasmic Cytochrome C Nitrite Reductase from Escherichia Coli Biochemistry, 41, 2002
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1H29
| Sulfate respiration in Desulfovibrio vulgaris Hildenborough: Structure of the 16-heme Cytochrome c HmcA at 2.5 A resolution and a view of its role in transmembrane electron transfer | 分子名称: | HEME C, HIGH-MOLECULAR-WEIGHT CYTOCHROME C | 著者 | Matias, P.M, Coelho, A.V, Valente, F.M.A, Placido, D, Legall, J, Xavier, A.V, Pereira, I.A.C, Carrondo, M.A. | 登録日 | 2002-08-01 | 公開日 | 2002-10-02 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Sulfate Respiration in Desulfovibrio Vulgaris Hildenborough: Structure of the 16-Heme Cytochrome C Hmca at 2.5 A Resolution and a View of its Role in Transmembrane Electron Transfer J.Biol.Chem., 277, 2002
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4YLJ
| Crystal structure of DYRK1A in complex with 10-Iodo-substituted 11H-indolo[3,2-c]quinoline-6-carboxylic acid inhibitor 5j | 分子名称: | 10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, ... | 著者 | Chaikuad, A, Falke, H, Nowak, R, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-05 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | 10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A. J.Med.Chem., 58, 2015
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5EXQ
| Human cytochrome c Y48H | 分子名称: | Cytochrome c, HEME C, SULFATE ION | 著者 | Fellner, M, Jameson, G.N.L, Ledgerwood, E.C, Wilbanks, S.M. | 登録日 | 2015-11-24 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity. Biochem.J., 2021
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3O1Y
| Electron transfer complexes: Experimental mapping of the redox-dependent cytochrome c electrostatic surface | 分子名称: | Cytochrome c, HEME C, NITRATE ION | 著者 | De March, M, De Zorzi, R, Demitri, N, Gabbiani, C, Guerri, A, Casini, A, Messori, L, Geremia, S. | 登録日 | 2010-07-22 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition. J. Inorg. Biochem., 135, 2014
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4YLL
| Crystal structure of DYRK1AA in complex with 10-Bromo-substituted 11H-indolo[3,2-c]quinolone-6-carboxylic acid inhibitor 5t | 分子名称: | 1,2-ETHANEDIOL, 10-bromo-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, ... | 著者 | Chaikuad, A, Falke, H, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-05 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | 10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A. J.Med.Chem., 58, 2015
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4YLK
| Crystal structure of DYRK1A in complex with 10-Chloro-substituted 11H-indolo[3,2-c]quinolone-6-carboxylic acid inhibitor 5s | 分子名称: | 1,2-ETHANEDIOL, 10-chloro-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, ... | 著者 | Chaikuad, A, Falke, H, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-05 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | 10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A. J.Med.Chem., 58, 2015
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3O20
| Electron transfer complexes:experimental mapping of the Redox-dependent Cytochrome C electrostatic surface | 分子名称: | Cytochrome c, HEME C, NITRATE ION | 著者 | De March, M, De Zorzi, R, Casini, A, Messori, L, Geremia, S, Demitri, N, Gabbiani, C, Guerri, A. | 登録日 | 2010-07-22 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition. J. Inorg. Biochem., 135, 2014
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4WTF
| CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GS-639475, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU | 分子名称: | 2'-C-methyluridine 5'-(trihydrogen diphosphate), CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Edwards, T.E, Appleby, T.C, Mcgrath, M.E. | 登録日 | 2014-10-30 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
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5DFS
| Crystal structure of Spider Monkey Cytochrome C at 1.15 Angstrom | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome c, ... | 著者 | MOU, T.C, McClelland, L.J, Jeakins-Cooley, M.E, Goldes, M.E, SPRANG, S.R, BOWLER, B.E. | 登録日 | 2015-08-27 | 公開日 | 2016-03-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Disruption of a hydrogen bond network in human versus spider monkey cytochrome c affects heme crevice stability. J.Inorg.Biochem., 158, 2016
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2X08
| cytochrome c peroxidase: ascorbate bound to the engineered ascorbate binding site | 分子名称: | ASCORBIC ACID, CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, ... | 著者 | Murphy, E.J, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E. | 登録日 | 2009-12-07 | 公開日 | 2010-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase. Biochemistry, 47, 2008
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5G03
| An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of Psammaplin C | 分子名称: | CARBONIC ANHYDRASE 2, PSAMMAPLIN C, SULFATE ION, ... | 著者 | Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S.A. | 登録日 | 2016-03-16 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
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5T7H
| Crystal structure of dimeric yeast iso-1-cytochrome C with CYMAL6 | 分子名称: | 6-cyclohexylhexan-1-ol, Cytochrome c iso-1, HEME C, ... | 著者 | Mcclelland, L, Mou, T.C, Sprang, S.R, Bowler, B.E. | 登録日 | 2016-09-05 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons. J. Am. Chem. Soc., 138, 2016
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5G01
| An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of Psammaplin C | 分子名称: | CARBONIC ANHYDRASE 2, PSAMMAPLIN C, SODIUM ION, ... | 著者 | Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S.A. | 登録日 | 2016-03-16 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
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5F2Q
| C-type lectin from Bothrops jararacussu | 分子名称: | C-type lectin BJcuL, CALCIUM ION, SODIUM ION | 著者 | de Padua, R.A.P, Pinheiro, M.P, Sartim, M.A, Sampaio, S.V, Nonato, M.C. | 登録日 | 2015-12-02 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | C-type lectin from Bothrops jararacussu To Be Published
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5TY3
| Crystal structure of K72A variant of Human Cytochrome c | 分子名称: | Cytochrome c, HEME C, SULFATE ION | 著者 | Mou, T.C, Nold, S.M, Lei, H, Sprang, S.R, Bowler, B.E. | 登録日 | 2016-11-18 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c. Biochemistry, 56, 2017
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