6TR0
 
 | | Solution structure of U2AF2 RRM1,2 | | 分子名称: | Splicing factor U2AF 65 kDa subunit | | 著者 | Kang, H.-S, Sattler, M. | | 登録日 | 2019-12-17 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5W0G
 | | Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ... | | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2017-05-30 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
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5W0H
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6XLW
 | | Crystal structure of U2AF65 bound to AdML splice site sequence | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ... | | 著者 | Maji, D, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2020-06-29 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
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6XLX
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6XLV
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7SN6
 | | U2AF65 UHM BOUND TO SF3B155 ULM5 | | 分子名称: | ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit | | 著者 | Loerch, S, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2021-10-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J.Biol.Chem., 298, 2022
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7S3A
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7S3B
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7S3C
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8P25
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7AAO
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7AAF
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4FXW
 | | Structure of phosphorylated SF1 complex with U2AF65-UHM domain | | 分子名称: | SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit | | 著者 | Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. | | 登録日 | 2012-07-03 | | 公開日 | 2013-01-16 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
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2HZC
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4Z2X
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2M52
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2M0G
 | | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition | | 分子名称: | Splicing factor 1, Splicing factor U2AF 65 kDa subunit | | 著者 | Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A. | | 登録日 | 2012-10-25 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res., 41, 2013
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4TU9
 | | STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DG*U)-3'), GLYCEROL, ... | | 著者 | Jenkins, J.L, McLaughlin, K.J, Agrawal, A.A, Kielkopf, C.L. | | 登録日 | 2014-06-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | | 主引用文献 | Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4TU8
 | | STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DA*U)-3'), ... | | 著者 | MCLAUGHLIN, K.J, JENKINS, J.L, Agrawal, A.A, KIELKOPF, C.L. | | 登録日 | 2014-06-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.918 Å) | | 主引用文献 | Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4TU7
 | | Structure of U2AF65 D231V variant with BrU5 DNA | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2014-06-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.087 Å) | | 主引用文献 | Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4RU2
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2G4B
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1U2F
 | | SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN OF HU2AF65 | | 分子名称: | PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT) | | 著者 | Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1999-05-26 | | 公開日 | 1999-08-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)).
EMBO J., 18, 1999
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2U2F
 | | SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN OF HU2AF65 | | 分子名称: | PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT) | | 著者 | Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1999-05-26 | | 公開日 | 1999-08-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)).
EMBO J., 18, 1999
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