PDB: 18 件ウェブページステータス検索Chemie searchBIRD

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7W1M	Cryo-EM structure of human cohesin-CTCF-DNA complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cohesin subunit SA-1, ... 著者 Shi, Z.B, Bai, X.C, Yu, H. 登録日 2021-11-19 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 CTCF and R-loops are boundaries of cohesin-mediated DNA looping. Mol.Cell, 83, 2023
7DG5	Crystal structure of mouse Smc1-Smc3 hinge domain containing a D574Y mutation 分子名称: Structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 3 著者 Seo, H, Noh, H, Oh, B.-H. 登録日 2020-11-11 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes. Elife, 10, 2021
6WG3	Cryo-EM structure of human Cohesin-NIPBL-DNA complex 分子名称: Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ... 著者 Shi, Z.B, Gao, H, Bai, X.C, Yu, H. 登録日 2020-04-04 公開日 2020-05-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
6WGE	Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1 分子名称: DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... 著者 Shi, Z.B, Gao, H, Bai, X.C, Yu, H. 登録日 2020-04-05 公開日 2020-05-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
2WD5	SMC hinge heterodimer (Mouse) 分子名称: STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A, STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 著者 Michie, K.A, Haering, C.H, Nasmyth, K, Lowe, J. 登録日 2009-03-20 公開日 2010-08-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A Positively Charged Channel within the Smc1/Smc3 Hinge Required for Sister Chromatid Cohesion. Embo J., 30, 2011
5D1C	Crystal structure of D233G-Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: GLYCEROL, HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, ... 著者 Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2015-08-04 公開日 2015-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.422 Å) 主引用文献 Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
5D1B	Crystal structure of G117E HDAC8 in complex with TSA 分子名称: Histone deacetylase 8, POTASSIUM ION, TRICHOSTATIN A, ... 著者 Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2015-08-04 公開日 2015-10-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
5D1D	Crystal structure of P91L-Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, POTASSIUM ION, ... 著者 Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2015-08-04 公開日 2015-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
6WG4	Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation 分子名称: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3 著者 Shi, Z.B, Yu, H. 登録日 2020-04-04 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
6WG6	Crystal structure of human SMC1-SMC3 hinge domain heterodimer in north-open conformation 分子名称: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3, poly(dT) 著者 Shi, Z.B, Yu, H. 登録日 2020-04-04 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.54 Å) 主引用文献 Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
4QA5	Crystal structure of A188T/Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA6	Crystal structure of I243N/Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.053 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA2	Crystal structure of I243N HDAC8 in complex with SAHA 分子名称: GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.377 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA1	Crystal structure of A188T HDAC8 in complex with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA4	Crystal structure of H334R HDAC8 in complex with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA3	Crystal structure of T311M HDAC8 in complex with Trichostatin A (TSA) 分子名称: GLYCEROL, Histone deacetylase 8, POTASSIUM ION, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.876 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA0	Crystal structure of C153F HDAC8 in complex with SAHA 分子名称: GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.242 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4QA7	Crystal structure of H334R/Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014