1YDL
 
 | | Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045. | | 分子名称: | general transcription factor IIH, polypeptide 5 | | 著者 | Forouhar, F, Edstrom, W, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-12-24 | | 公開日 | 2005-02-08 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045.
To be Published
|
|
2JNJ
 | | Solution structure of the p8 TFIIH subunit | | 分子名称: | TFIIH basal transcription factor complex TTD-A subunit | | 著者 | Vitorino, M, Atkinson, R.A, Moras, D, Poterszman, A, Kieffer, B, Structural Proteomics in Europe 2 (SPINE-2) | | 登録日 | 2007-01-26 | | 公開日 | 2007-04-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure and Self-association Properties of the p8 TFIIH Subunit Responsible for Trichothiodystrophy
J.Mol.Biol., 368, 2007
|
|
3DGP
 | | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | | 分子名称: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | | 著者 | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | | 登録日 | 2008-06-14 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
|
|
3DOM
 | | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | | 分子名称: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | | 著者 | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | | 登録日 | 2008-07-04 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
|
|
5FMF
 | | the P-lobe of RNA polymerase II pre-initiation complex | | 分子名称: | DNA REPAIR HELICASE RAD25, SSL2, DNA REPAIR HELICASE RAD3, ... | | 著者 | Murakami, K, Tsai, K, Kalisman, N, Bushnell, D.A, Asturias, F.J, Kornberg, R.D. | | 登録日 | 2015-11-03 | | 公開日 | 2015-11-25 | | 最終更新日 | 2017-07-12 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Structure of an RNA Polymerase II Pre-Initiation Complex
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
5IY8
 | | Human holo-PIC in the initial transcribing state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
|
|
5IY6
 | | Human holo-PIC in the closed state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
|
|
5IY9
 | | Human holo-PIC in the initial transcribing state (no IIS) | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
|
|
5IVW
 | | Human core TFIIH bound to DNA within the PIC | | 分子名称: | General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-21 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
|
|
5IY7
 | | Human holo-PIC in the open state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
|
|
5SVA
 | | Mediator-RNA Polymerase II Pre-Initiation Complex | | 分子名称: | 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... | | 著者 | Robinson, P.J, Bushnell, D.A, Kornberg, R.D. | | 登録日 | 2016-08-05 | | 公開日 | 2016-09-28 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (15.3 Å) | | 主引用文献 | Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
|
|
5OF4
 | | The cryo-EM structure of human TFIIH | | 分子名称: | General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4,p52,General transcription factor IIH subunit 4, ... | | 著者 | Greber, B.J, Nguyen, T.H.D, Fang, J, Afonine, P.V, Adams, P.D, Nogales, E. | | 登録日 | 2017-07-10 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | The cryo-electron microscopy structure of human transcription factor IIH.
Nature, 549, 2017
|
|
5OQJ
 | | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | | 分子名称: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | | 登録日 | 2017-08-11 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017
|
|
5OQM
 | | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. | | 登録日 | 2017-08-13 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017
|
|
6GYM
 | | Structure of a yeast closed complex with distorted DNA (CCdist) | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | | 登録日 | 2018-06-30 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Mol. Cell, 73, 2019
|
|
6NMI
 | | Cryo-EM structure of the human TFIIH core complex | | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... | | 著者 | Greber, B.J, Toso, D, Fang, J, Nogales, E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-03-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The complete structure of the human TFIIH core complex.
Elife, 8, 2019
|
|
6O9M
 | | Structure of the human apo TFIIH | | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ... | | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | | 登録日 | 2019-03-14 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6O9L
 | | Human holo-PIC in the closed state | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | | 登録日 | 2019-03-14 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6RO4
 | | Structure of the core TFIIH-XPA-DNA complex | | 分子名称: | DNA repair protein complementing XP-A cells, DNA1, DNA2, ... | | 著者 | Kokic, G, Chernev, A, Tegunov, D, Dienemann, C, Urlaub, H, Cramer, P. | | 登録日 | 2019-05-10 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of TFIIH activation for nucleotide excision repair.
Nat Commun, 10, 2019
|
|
6TRS
 | | Crystal structure of TFIIH subunit p52 in complex with p8 | | 分子名称: | RNA polymerase II transcription factor B subunit 2, Uncharacterized protein | | 著者 | Koelmel, W, Kuper, J, Schoenwetter, E, Kisker, C. | | 登録日 | 2019-12-19 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | How to limit the speed of a motor: the intricate regulation of the XPB ATPase and translocase in TFIIH.
Nucleic Acids Res., 48, 2020
|
|
7LBM
 | | Structure of the human Mediator-bound transcription pre-initiation complex | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Abdella, R, Talyzina, A, He, Y. | | 登録日 | 2021-01-08 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structure of the human Mediator-bound transcription preinitiation complex.
Science, 372, 2021
|
|
7NVV
 | | XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ... | | 著者 | Aibara, S, Schilbach, S, Cramer, P. | | 登録日 | 2021-03-16 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
|
|
7NVY
 | | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | | 分子名称: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Aibara, S, Schilbach, S, Cramer, P. | | 登録日 | 2021-03-16 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
|
|
7NVX
 | | TFIIH in a post-translocated state (with ADP-BeF3) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | | 著者 | Aibara, S, Schilbach, S, Cramer, P. | | 登録日 | 2021-03-16 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
|
|
7NW0
 | | RNA polymerase II pre-initiation complex with open promoter DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | | 著者 | Aibara, S, Schilbach, S, Cramer, P. | | 登録日 | 2021-03-16 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
|
|
