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5K68
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Designed Artificial Cupredoxins
分子名称: Streptavidin, [CuII(biot-bu-dpea)]2+
著者Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S.
登録日2016-05-24
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Modular Artificial Cupredoxins.
J.Am.Chem.Soc., 138, 2016
3EW2
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Crystal structure of rhizavidin-biotin complex
分子名称: BIOTIN, rhizavidin
著者Livnah, O, Meir, A.
登録日2008-10-14
公開日2008-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer.
J.Mol.Biol., 386, 2009
5F2B
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Expanding Nature's Catalytic Repertoire -Directed Evolution of an Artificial Metalloenzyme for In Vivo Metathesis
分子名称: SULFATE ION, Streptavidin, [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium
著者Heinisch, T, Jeschek, M, Reuter, R, Trindler, C, Panke, S, Ward, T.R.
登録日2015-12-01
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Directed evolution of artificial metalloenzymes for in vivo metathesis.
Nature, 537, 2016
4U46
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Crystal structure of an avidin mutant
分子名称: Avidin, CHLORIDE ION
著者Agrawal, N, Lehtonen, S, Kahkonen, N, Riihimaki, T, Hytonen, V.P, Kulomaa, M.S, Johnson, M.S, Airenne, T.T.
登録日2014-07-23
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Artificial Avidin-Based Receptors for a Panel of Small Molecules.
Acs Chem.Biol., 11, 2016
5TO2
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Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
分子名称: DI(HYDROXYETHYL)ETHER, Streptavidin
著者Zhang, M, Biswas, S, Deng, W, Yu, H.
登録日2016-10-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
To Be Published
7NLV
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WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE II
分子名称: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, Streptavidin
著者Nodling, A.R, Santi, N, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y.
登録日2021-02-22
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献The role of streptavidin and its variants in catalysis by biotinylated secondary amines.
Org.Biomol.Chem., 19, 2021
8QQ3
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Streptavidin with a Ni-cofactor
分子名称: 4-[4-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butylamino]-~{N}1,~{N}1'-di(quinolin-8-yl)cyclohexane-1,1-dicarboxamide, NICKEL (II) ION, Streptavidin
著者Zhang, K, Jakob, R.P, Ward, T.R.
登録日2023-10-03
公開日2024-02-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献An artificial nickel chlorinase based on the biotin-streptavidin technology.
Chem.Commun.(Camb.), 60, 2024
4OKA
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Structural-, Kinetic- and Docking Studies of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis
分子名称: IRIDIUM ION, Streptavidin, [N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamidato]iridium(III)
著者Schirmer, T, Heinisch, T.
登録日2014-01-22
公開日2014-11-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.505 Å)
主引用文献Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis
J.Am.Chem.Soc., 136, 2014
7ALX
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Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes
分子名称: ((4S)-1,3-dimesityl-4-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)imidazolidin-2-yl)gold, Streptavidin,Superoxide dismutase [Cu-Zn],Streptavidin
著者Igareta, N.V, Christoffel, F, Peterson, R.L, Ward, T.R.
登録日2020-10-07
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis
Nat Catal, 4, 2021
7B74
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Chimeric Streptavidin With A Dimerization Domain For Artificial Transfer Hydrogenation
分子名称: Streptavidin,Superoxide dismutase [Cu-Zn],Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III)
著者Igareta, N.V, Ward, T.R.
登録日2020-12-09
公開日2021-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Spiers Memorial Lecture: Shielding the active site: a streptavidin superoxide-dismutase chimera as a host protein for asymmetric transfer hydrogenation.
Faraday Disc.Chem.Soc, 2023
3FDC
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Crystal Structure of Avidin
分子名称: Avidin, iron(II) tetracyano-5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid (4'-methyl-[2,2']bipyridinyl-4-ylmethyl)-amide
著者Barker, K.D, Sazinsky, M.H, Eckermann, A.L, Abajian, C, Hartings, M.R, Rosenzweig, A.C, Meade, T.J.
登録日2008-11-25
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Protein Binding and the Electronic Properties of Iron(II) Complexes: An Electrochemical and Optical Investigation of Outer Sphere Effects.
Bioconjug.Chem., 20, 2009
7ZN1
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Avidin + Biotin-Tempo
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)hexanamide, ...
著者Milani, J, Lau, K, Pojer, F, Ansermet, J.P, Saenz, F.
登録日2022-04-20
公開日2023-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Avidin + Biotin-Tempo
To Be Published
7ZYL
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Avidin + Biotin-Tempo
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)hexanamide, Avidin
著者Milani, J, Myasnikov, A, Beckert, B, Nazarov, S, Ansermet, J.P, Saenz, F.
登録日2022-05-25
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Avidin + Biotin-Tempo
To Be Published
6J6K
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Apo-state streptavidin
分子名称: Streptavidin
著者Fan, X, Wang, J, Lei, J.L, Wang, H.W.
登録日2019-01-15
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution.
Nat Commun, 10, 2019
6J6J
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Biotin-bound streptavidin
分子名称: BIOTIN, Streptavidin
著者Fan, X, Wang, J, Lei, J.L, Wang, H.W.
登録日2019-01-15
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution.
Nat Commun, 10, 2019
6LNG
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Rapid crystallization of streptavidin using charged peptides
分子名称: GLYCEROL, Streptavidin
著者Minamihata, K, Tsukamoto, K, Adachi, M, Shimizu, R, Mishina, M, Kuroki, R, Nagamune, T.
登録日2019-12-30
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8000015 Å)
主引用文献Genetically fused charged peptides induce rapid crystallization of proteins.
Chem.Commun.(Camb.), 56, 2020
4Y59
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Crystal structure of ALiS1-Streptavidin complex
分子名称: 2-[3-(trifluoromethyl)phenyl]furo[3,2-c]pyridin-4(5H)-one, Streptavidin
著者Sugiyama, S, Terai, T, Kohno, M, Ishida, H, Nagano, T.
登録日2015-02-11
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
J.Am.Chem.Soc., 137, 2015
3MG5
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Core-streptavidin mutant F130L in complex with biotin
分子名称: BIOTIN, GLYCEROL, Streptavidin
著者Le Trong, I, Baugh, L, Stayton, P.S, Lybrand, T.P, Stenkamp, R.E.
登録日2010-04-05
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A distal point mutation in the streptavidin-biotin complex preserves structure but diminishes binding affinity: experimental evidence of electronic polarization effects?
Biochemistry, 49, 2010
4Y5D
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CRYSTAL STRUCTURE OF ALiS2-STREPTAVIDIN COMPLEX
分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, DIMETHYL SULFOXIDE, HEXAETHYLENE GLYCOL, ...
著者Sugiyama, S, Terai, T, Kohno, M, Ishida, H, Nagano, T.
登録日2015-02-11
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
J.Am.Chem.Soc., 137, 2015
3MM0
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Crystal structure of chimeric avidin
分子名称: Avidin, Avidin-related protein 4/5
著者Livnah, O, Eisenberg-Domovich, Y, Maatta, J.A.E, Kulomaa, M.S, Hytonen, V.P, Nordlund, H.R.
登録日2010-04-19
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Chimeric avidin shows stability against harsh chemical conditions-biochemical analysis and 3D structure.
Biotechnol.Bioeng., 108, 2011
6M9B
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Wild-type streptavidin in complex with biotin solved by native SAD with data collected at 6 keV
分子名称: BIOTIN, Streptavidin
著者Finke, A.D.
登録日2018-08-23
公開日2019-04-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.548 Å)
主引用文献Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source.
Acta Crystallogr D Struct Biol, 75, 2019
3EW1
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Crystal structure of rhizavidin
分子名称: rhizavidin
著者Livnah, O, Meir, A.
登録日2008-10-14
公開日2008-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer.
J.Mol.Biol., 386, 2009
5L3Y
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Designed Artificial Cupredoxins
分子名称: Streptavidin, [CuII(biot-et-dpea)]2+
著者Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S.
登録日2016-05-24
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modular Artificial Cupredoxins.
J.Am.Chem.Soc., 138, 2016
4IRW
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Co-crystallization of streptavidin-biotin complex with a lanthanide-ligand complex gives rise to a novel crystal form
分子名称: BIOTIN, PYRIDINE-2,6-DICARBOXYLIC ACID, SODIUM ION, ...
著者Bandara, R.A.M.S.S, Liu, D.Q, Hindupur, A, Tesh, K.F, Fox, R.O.
登録日2013-01-15
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.396 Å)
主引用文献Co-crystallization of streptavidin-biotin complex with a lanthanide-ligand complex gives rise to a novel crystal form
To be Published
1SWU
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STREPTAVIDIN MUTANT Y43F
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, STREPTAVIDIN
著者Freitag, S, Le Trong, I, Klumb, L.A, Stayton, P.S, Stenkamp, R.E.
登録日1998-10-12
公開日1999-11-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site?
Acta Crystallogr.,Sect.D, 55, 1999

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