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4F2K
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BU of 4f2k by Molmil
Macrophage Migration Inhibitory Factor covalently complexed with phenethylisothiocyanate
分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ...
著者Tyndall, J.D.A, Bernhagen, J, Hampton, M.B, Wilbanks, S.M, Rutledge, M.T.
登録日2012-05-08
公開日2012-06-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate
Acta Crystallogr.,Sect.F, 68, 2012
8IMR
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BU of 8imr by Molmil
Structure of ligand-free human macrophage migration inhibitory factor
分子名称: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H.
登録日2023-03-07
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis
To Be Published
5J7P
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BU of 5j7p by Molmil
Macrophage Migration Inhibitory Factor bound to Covalent Inhibitor RDR03785
分子名称: 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Jorgensen, W.L.
登録日2016-04-06
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Irregularities in enzyme assays: The case of macrophage migration inhibitory factor.
Bioorg.Med.Chem.Lett., 26, 2016
5XEJ
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BU of 5xej by Molmil
Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX
分子名称: (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, Macrophage migration inhibitory factor, SULFATE ION
著者Takimoto-Kamimura, M, Fukushima, K.
登録日2017-04-05
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of macrophage migration inhibitory factor in complex with methotrexate.
Acta Crystallogr D Struct Biol, 77, 2021
3CE4
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BU of 3ce4 by Molmil
Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Crichlow, G.V, Lolis, E.
登録日2008-02-28
公開日2008-12-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
2GDG
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BU of 2gdg by Molmil
Crystal structure of covalently modified macrophage inhibitory factor
分子名称: Macrophage migration inhibitory factor
著者Golubkov, P.A, Hackert, M.L.
登録日2006-03-16
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate.
Bioorg.Chem., 34, 2006
3L5T
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BU of 3l5t by Molmil
Crystal structure of macrophage migration inhibitory factor (MIF) with thiophenepiperazinylquinolinone inhibitor at 1.86A resolution
分子名称: 1-methyl-2-oxo-4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]-1,2-dihydroquinoline-3-carbonitrile, Macrophage migration inhibitory factor, SULFATE ION
著者McLean, L, Zhang, Y.
登録日2009-12-22
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site.
Bioorg.Med.Chem.Lett., 20, 2010
4XX8
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BU of 4xx8 by Molmil
Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor
分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION
著者Pantouris, G, Lolis, E.
登録日2015-01-30
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
6LR3
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BU of 6lr3 by Molmil
Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum
分子名称: Macrophage migration inhibitory factor, SULFATE ION
著者Su, Z.M, Tian, X.Y, Li, H.J, Wei, Z.M, Chen, L.F, Ren, H.X, Peng, W.F, Tang, C.T.
登録日2020-01-15
公開日2020-07-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum.
Biochem.J., 477, 2020
8AP3
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BU of 8ap3 by Molmil
Structure of A. thaliana MIF/D-DT-like protein-2 (MDL2)
分子名称: MIF homologue
著者Manjula, R, Basquin, J, Lolis, E.
登録日2022-08-09
公開日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of A. thaliana MIF/D-DT-like protein-2 (MDL2)
To Be Published
1UIZ
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BU of 1uiz by Molmil
Crystal Structure Of Macrophage Migration Inhibitory Factor From Xenopus Laevis.
分子名称: Macrophage Migration Inhibitory Factor
著者Suzuki, M, Takamura, Y, Maeno, M, Tochinai, S, Iyaguchi, D, Tanaka, I, Nishihira, J, Ishibashi, T.
登録日2003-07-24
公開日2004-05-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Xenopus laevis Macrophage Migration Inhibitory Factor Is Essential for Axis Formation and Neural Development.
J.Biol.Chem., 279, 2004
1P1G
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BU of 1p1g by Molmil
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) WITH PRO-1 MUTATED TO GLY-1
分子名称: PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR)
著者Lubetsky, J.B, Lolis, E.
登録日1999-03-24
公開日1999-06-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.
Biochemistry, 38, 1999
2WKF
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BU of 2wkf by Molmil
Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum
分子名称: GLYCEROL, MACROPHAGE MIGRATION INHIBITORY FACTOR
著者Dobson, S.E, Augustijn, K.D, Brannigan, J.A, Dodson, E.J, Waters, A.P, Wilkinson, A.J.
登録日2009-06-11
公開日2009-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei.
Protein Sci., 18, 2009
6ICE
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BU of 6ice by Molmil
Crystal structure of Hamster MIF
分子名称: Macrophage migration inhibitory factor
著者Sundaram, R, Vasudevan, D.
登録日2018-09-05
公開日2019-09-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer.
Sci Rep, 9, 2019
1LJT
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BU of 1ljt by Molmil
Crystal Structure of Macrophage Migration Inhibitory Factor complexed with (S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole-acetic acid methyl ester (ISO-1)
分子名称: 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER, Macrophage migration inhibitory factor
著者Lubetsky, J.B, Dios, A, Han, J, Aljabari, B, Ruzsicska, B, Mitchell, R, Lolis, E, Al-Abed, Y.
登録日2002-04-22
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents
J.Biol.Chem., 277, 2002
4K9G
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BU of 4k9g by Molmil
1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound
分子名称: (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one, 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one, CHLORIDE ION, ...
著者Crichlow, G.V, Al-Abed, Y, Lolis, E.J.
登録日2013-04-19
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.
INT J ONCOL., 45, 2014
7KQX
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BU of 7kqx by Molmil
MIF Y99C homotrimeric mutant
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Manjula, R, Georgios, P, Lolis, E.J.
登録日2020-11-18
公開日2022-01-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies.
Front Mol Biosci, 9, 2022
8UZ4
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BU of 8uz4 by Molmil
Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (Apo, P41212 form)
分子名称: MACROPHAGE MIGRATION INHIBITORY FACTOR
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-11-14
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of macrophage migration inhibitory factor (MIF) from Trichomonas vaginalis (Apo, P41212 form)
To be published
4TRF
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BU of 4trf by Molmil
Crystal structure of Macrophage Migration Inhibitory Factor in complex with N-(pyridin-3-ylmethyl)thioformamide
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Pantouris, G, Lolis, E.
登録日2014-06-16
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
8VJ2
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BU of 8vj2 by Molmil
Crystal Structure of Macrophage migration inhibitory factor-1 (MIF1) from Onchocerca volvulus
分子名称: Macrophage migration inhibitory factor-1, SODIUM ION
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-05
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Macrophage migration inhibitory factor-1 (MIF1) from Onchocerca volvulus
To be published
6LKW
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BU of 6lkw by Molmil
Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum
分子名称: CHLORIDE ION, Macrophage migration inhibitory factor
著者Su, Z.M, Tian, X.Y, Li, H.J, Wei, Z.M, Chen, L.F, Ren, H.X, Peng, W.F, Tang, C.T.
登録日2019-12-20
公開日2020-07-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum.
Biochem.J., 477, 2020
4TRU
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BU of 4tru by Molmil
Crystal structure of Q24A Q25A mutant of human macrophage migration inhibitory factor
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Pantouris, G, Lolis, E.
登録日2014-06-17
公開日2015-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4WRB
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Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-190)
分子名称: 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L.
登録日2014-10-23
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.
J.Am.Chem.Soc., 137, 2015
4WR8
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Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180)
分子名称: 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ...
著者Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L.
登録日2014-10-23
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.
J.Am.Chem.Soc., 137, 2015
6FVE
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Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound FITC
分子名称: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid, Macrophage migration inhibitory factor, SULFATE ION
著者Samygina, V.R, Bourenkov, G, Sokolov, A.V.
登録日2018-03-02
公開日2018-06-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor.
Biochemistry Mosc., 83, 2018

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