5KUM
| Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2 | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION, ... | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | 登録日 | 2016-07-13 | 公開日 | 2016-08-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids. J.Gen.Physiol., 148, 2016
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7ADI
| KirBac3.1 W46R: role of a highly conserved tryptophan at the membrane-water interface of Kir channel | 分子名称: | Inward rectifier potassium channel Kirbac3.1, MAGNESIUM ION, POTASSIUM ION | 著者 | Venien-Bryan, C, Fagnen, C, De Zorzi, R, Bannwarth, L, Oubella, I, Haouz, A. | 登録日 | 2020-09-15 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain. Int J Mol Sci, 23, 2021
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4LP8
| A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Inward rectifier potassium channel Kirbac3.1, ... | 著者 | Zubcevic, L, Bavro, V.N, Muniz, J.R.C, Schmidt, M.R, Wang, S, De Zorzi, R, Venien-Bryan, C, Sansom, M.S.P, Nichols, C.G, Tucker, S.J. | 登録日 | 2013-07-15 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains. J.Biol.Chem., 289, 2014
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5KUK
| Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | 登録日 | 2016-07-13 | 公開日 | 2016-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids. J.Gen.Physiol., 148, 2016
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2QKS
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3ZRS
| X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at the bundle-crossing gate. | 分子名称: | ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION | 著者 | Bavro, V.N, De Zorzi, R, Schmidt, M.R, Muniz, J.R.C, Zubcevic, L, Sansom, M.S.P, Venien-Bryan, C, Tucker, S.J. | 登録日 | 2011-06-17 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating Nat.Struct.Mol.Biol., 19, 2012
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8I5M
| Rat Kir4.1 in complex with PIP2 | 分子名称: | ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Zhao, C, Guo, J. | 登録日 | 2023-01-26 | 公開日 | 2024-02-28 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses. Nat.Chem.Biol., 20, 2024
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8I5N
| Rat Kir4.1 in complex with PIP2 and Lys05 | 分子名称: | ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Zhao, C, Guo, J. | 登録日 | 2023-01-26 | 公開日 | 2024-02-28 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses. Nat.Chem.Biol., 20, 2024
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1XL6
| Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1 | 分子名称: | Inward rectifier potassium channel, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Gulbis, J.M, Kuo, A, Smith, B, Doyle, D.A, Edwards, A, Arrowsmith, C, Sundstrom, M. | 登録日 | 2004-09-30 | 公開日 | 2004-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Two intermediate gating state crystal structures of the KirBac3.1 K+ channel To be Published
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3JYC
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1XL4
| Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1 | 分子名称: | Inward rectifier potassium channel, MAGNESIUM ION, POTASSIUM ION | 著者 | Gulbis, J.M, Kuo, A, Smith, B, Doyle, D.A, Edwards, A, Arrowsmith, C, Sundstrom, M. | 登録日 | 2004-09-30 | 公開日 | 2004-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two intermediate gating state crystal structures of the KirBac3.1 K+ channel To be Published
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3K6N
| Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain | 分子名称: | G protein-activated inward rectifier potassium channel 1, SODIUM ION | 著者 | Xu, Y, Shin, H.G, Szep, S, Lu, Z. | 登録日 | 2009-10-09 | 公開日 | 2009-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Physical determinants of strong voltage sensitivity of K(+) channel block. Nat.Struct.Mol.Biol., 16, 2009
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6O9U
| KirBac3.1 at a resolution of 2 Angstroms | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3,3',3''-phosphoryltripropanoic acid, BARIUM ION, ... | 著者 | Gulbis, J.M, Clarke, O.B. | 登録日 | 2019-03-15 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A constricted opening in Kir channels does not impede potassium conduction. Nat Commun, 11, 2020
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6O9T
| KirBac3.1 mutant at a resolution of 4.1 Angstroms | 分子名称: | 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Inward rectifier potassium channel Kirbac3.1, POTASSIUM ION | 著者 | Gulbis, J.M, Black, K.A, Miller, D.M. | 登録日 | 2019-03-15 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | 主引用文献 | A constricted opening in Kir channels does not impede potassium conduction. Nat Commun, 11, 2020
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6O9V
| KirBac3.1 mutant at a resolution of 3.1 Angstroms | 分子名称: | 1,1-Methanediyl Bismethanethiosulfonate, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Inward rectifier potassium channel Kirbac3.1, ... | 著者 | Gulbis, J.M, Black, K.A, Miller, D.M. | 登録日 | 2019-03-15 | 公開日 | 2020-05-27 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | 主引用文献 | A constricted opening in Kir channels does not impede potassium conduction. Nat Commun, 11, 2020
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6M85
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6M86
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6M84
| Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | 著者 | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | 登録日 | 2018-08-21 | 公開日 | 2019-09-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152, 2020
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7ZDZ
| Cryo-EM structure of the human inward-rectifier potassium 2.1 channel (Kir2.1) | 分子名称: | Inward rectifier potassium channel 2, POTASSIUM ION, STRONTIUM ION | 著者 | Fernandes, C.A.H, Venien-Bryan, C, Fagnen, C, Zuniga, D. | 登録日 | 2022-03-30 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-electron microscopy unveils unique structural features of the human Kir2.1 channel. Sci Adv, 8, 2022
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6XIS
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6XIT
| Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with PIP2 | 分子名称: | G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Niu, Y, Tao, X, MacKinnon, R. | 登録日 | 2020-06-21 | 公開日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels. Elife, 9, 2020
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6XEU
| CryoEM structure of GIRK2PIP2* - G protein-gated inwardly rectifying potassium channel GIRK2 with PIP2 | 分子名称: | G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION, ... | 著者 | Mathiharan, Y.K, Glaaser, I.W, Skiniotis, G, Slesinger, P.A. | 登録日 | 2020-06-13 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into GIRK2 channel modulation by cholesterol and PIP2 Cell Rep, 36, 2021
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6XEV
| CryoEM structure of GIRK2-PIP2/CHS - G protein-gated inwardly rectifying potassium channel GIRK2 with modulators cholesteryl hemisuccinate and PIP2 | 分子名称: | CHOLESTEROL HEMISUCCINATE, G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, ... | 著者 | Mathiharan, Y.K, Glaaser, I.W, Skiniotis, G, Slesinger, P.A. | 登録日 | 2020-06-14 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into GIRK2 channel modulation by cholesterol and PIP2 Cell Rep, 36, 2021
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7S5T
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7N9L
| KirBac3.1 C71S C262S | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Inward rectifier potassium channel Kirbac3.1, POTASSIUM ION, ... | 著者 | Gulbis, J.M, Black, K.A. | 登録日 | 2021-06-18 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ion currents through Kir potassium channels are gated by anionic lipids. Nat Commun, 13, 2022
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